Structure of Human Thymidylate Synthase Suggests Advantages of Chemotherapy with Noncompetitive Inhibitors

Autor: Phan, Jason ^‡, Steadman, David J. ^{‡, §}, Koli, Sangita ^{‡, §}, Ding, Weirong C. ^‡, Minor, Wladek ^¶, Dunlap, R. Bruce ^‡, Berger, Sondra H. ^{§, ‖}, Lebioda, Lukasz ^{‡, ‖}

Publikováno v: In Journal of Biological Chemistry 27 April 2001 276(17):14170-14177

Substitution at residue 214 of human thymidylate synthase alters nucleotide binding and...

Autor: Steadman, David J., Spencer, H. Trent

Publikováno v: Biochemistry; 04/27/99, Vol. 38 Issue 17, p5582, 6p, 3 Diagrams, 5 Charts, 1 Graph

Occurrence of NKX3.1 C154T polymorphism in men with and without prostate cancer and studies of its effect on protein function.

Autor: Gelmann EP; Department of Oncology, Lombardi Cancer Center, Georgetown University School of Medicine, Washington, DC 20007-2197, USA. gelmanne@georgetown.edu, Steadman DJ, Ma J, Ahronovitz N, Voeller HJ, Swope S, Abbaszadegan M, Brown KM, Strand K, Hayes RB, Stampfer MJ

Publikováno v: Cancer research [Cancer Res] 2002 May 01; Vol. 62 (9), pp. 2654-9.