Rapid cleavage of RNA by RNase E in the absence of 5′ monophosphate stimulation

Autor: Kime, L, Jourdan, SS, Stead, JA, Hidalgo-Sastre, A, McDowall, KJ

The best characterized pathway for the initiation of mRNA degradation in Escherichia coli involves the removal of the 5′‐terminal pyrophosphate to generate a monophosphate group that stimulates endonucleolytic cleavage by RNase E. We show here ho

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Quality Improvement Intervention for Reduction of Redundant Testing.

Autor: Ducatman AM; School of Public Health, West Virginia University, Morgantown, WV, USA., Tacker DH; Department of Pathology, West Virginia University School of Medicine, Morgantown, WV, USA., Ducatman BS; Department of Pathology, West Virginia University School of Medicine, Morgantown, WV, USA., Long D; University of Alabama School of Public Health, Birmingham, AL, USA., Perrotta PL; Department of Pathology, West Virginia University School of Medicine, Morgantown, WV, USA., Lawther H; Department of Radiology, Mayo School of Graduate Medical Education, Scottsdale, AZ, USA., Pennington K; Department of Internal Medicine, Mayo School of Graduate Medical Education, Rochester, MN, USA., Lander O; Department of Emergency Medicine, West Virginia University School of Medicine, Morgantown, WV, USA., Warden M; Department of Internal Medicine, West Virginia University School of Medicine, Morgantown, WV, USA., Failinger C; Heart Institute, West Virginia University School of Medicine, Morgantown, WV, USA., Halbritter K; Department of Internal Medicine, West Virginia University School of Medicine, Morgantown, WV, USA., Pellegrino R; Department of Internal Medicine, West Virginia University School of Medicine, Morgantown, WV, USA., Treese M; Department of Emergency Medicine, Jefferson Medical Center, Ranson, WV, USA., Stead JA; Department of Pathology, Jefferson Medical Center Medical Center, Ranson, WV, USA.; Department of Pathology, Berkeley Medical Center, Martinsburg, WV, USA., Glass E; Department of Emergency Medicine, Berkeley Medical Center, Martinsburg, WV, USA., Cianciaruso L; Inova Medical Group, Falls Church, VA, USA., Nau KC; Department of Family Medicine and Office of the Dean, Robert C Byrd Health Sciences Center-Eastern campus, Harpers Ferry, WV, USA.

Publikováno v: Academic pathology [Acad Pathol] 2017 May 28; Vol. 4, pp. 2374289517707506. Date of Electronic Publication: 2017 May 28 (Print Publication: 2017).

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Structural basis for DNA strand separation by a hexameric replicative helicase.

Autor: Chaban Y; Department of Biological Sciences, Birkbeck College, Institute of Structural and Molecular Biology, Malet Street, London WC1E 7HX, UK., Stead JA; Academic Unit of Molecular Oncology, University of Sheffield Medical School, Beech Hill Road, Sheffield S10 2RX, UK., Ryzhenkova K; Department of Biological Sciences, Birkbeck College, Institute of Structural and Molecular Biology, Malet Street, London WC1E 7HX, UK., Whelan F; Departament of Biolody, University of York, York YO10 5DD, UK., Lamber EP; Department of Biological Sciences, Birkbeck College, Institute of Structural and Molecular Biology, Malet Street, London WC1E 7HX, UK., Antson A; Departament of Biolody, University of York, York YO10 5DD, UK., Sanders CM; Academic Unit of Molecular Oncology, University of Sheffield Medical School, Beech Hill Road, Sheffield S10 2RX, UK c.m.sanders@sheffield.ac.uk., Orlova EV; Department of Biological Sciences, Birkbeck College, Institute of Structural and Molecular Biology, Malet Street, London WC1E 7HX, UK e.orlova@mail.cryst.bbk.ac.uk.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2015 Sep 30; Vol. 43 (17), pp. 8551-63. Date of Electronic Publication: 2015 Aug 03.

The C-terminal region of the exosome-associated protein Rrp47 is specifically required for box C/D small nucleolar RNA 3'-maturation.

Autor: Costello JL; Department of Molecular Biology and Biotechnology, The University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, United Kingdom., Stead JA, Feigenbutz M, Jones RM, Mitchell P

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2011 Feb 11; Vol. 286 (6), pp. 4535-43. Date of Electronic Publication: 2010 Dec 06.