Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Stavroula Petridi"'
Autor:
Stavroula Petridi, C. Adam Middleton, Chris Ugbode, Alison Fellgett, Laura Covill, Christopher J. H. Elliott
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 6, Pp 1903-1914 (2020)
LRRK2 mutations cause Parkinson’s, but the molecular link from increased kinase activity to pathological neurodegeneration remains undetermined. Previous in vitro assays indicate that LRRK2 substrates include at least 8 Rab GTPases. We have now exa
Externí odkaz:
https://doaj.org/article/c9152bed61de45eeb9a64e98cead706c
Autor:
Panagiotis Tsapras, Stavroula Petridi, Selina Chan, Marta Geborys, Anne-Claire Jacomin, Antonia P. Sagona, Pascal Meier, Ioannis P. Nezis
Publikováno v:
Cell Reports, Vol 38, Iss 4, Pp 110286- (2022)
Summary: Selective autophagy is a catabolic route that turns over specific cellular material for degradation by lysosomes, and whose role in the regulation of innate immunity is largely unexplored. Here, we show that the apical kinase of the Drosophi
Externí odkaz:
https://doaj.org/article/7bcd2a950cbc4ddd993881f146b2b3de
Autor:
Yu-En Lin, Chin-Hsien Lin, En-Peng Ho, Yi-Ci Ke, Stavroula Petridi, Christopher JH Elliott, Lee-Yan Sheen, Cheng-Ting Chien
Publikováno v:
eLife, Vol 10 (2021)
The most frequent missense mutations in familial Parkinson’s disease (PD) occur in the highly conserved LRRK2/PARK8 gene with G2019S mutation. We previously established a fly model of PD carrying the LRRK2-G2019S mutation that exhibited the parkins
Externí odkaz:
https://doaj.org/article/34ae0637a2cd4bcf8f28c5b290a95ecd
Autor:
Anne-Claire Jacomin, Stavroula Petridi, Marisa Di Monaco, Zambarlal Bhujabal, Ashish Jain, Nitha C. Mulakkal, Anthimi Palara, Emma L. Powell, Bonita Chung, Cleidiane Zampronio, Alexandra Jones, Alexander Cameron, Terje Johansen, Ioannis P. Nezis
Publikováno v:
Cell Reports, Vol 31, Iss 8, Pp - (2020)
Summary: Autophagy is the degradation of cytoplasmic material through the lysosomal pathway. One of the most studied autophagy-related proteins is LC3. Despite growing evidence that LC3 is enriched in the nucleus, its nuclear role is poorly understoo
Externí odkaz:
https://doaj.org/article/4c659952edc443cfb7875849b87d2315
Publikováno v:
Development. 149
Neural stem cells (NSCs) in the developing and adult brain undergo many different transitions, tightly regulated by extrinsic and intrinsic factors. While the role of signalling pathways and transcription factors is well established, recent evidence
Autor:
Yi-Ci Ke, Cheng-Ting Chien, Lee-Yan Sheen, Chin-Hsien Lin, En-Peng Ho, Christopher J. H. Elliott, Yu-En Lin, Stavroula Petridi
The most frequent missense mutations in familial Parkinson’s disease (PD) occur in the highly conserved LRRK2/PARK8 gene with G2019S mutation. We previously established a fly model of PD carrying the LRRK2-G2019S mutation that exhibited the parkins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4c3744e47c2a4b2cddd58e161e4cd89
https://doi.org/10.1101/2021.08.25.457612
https://doi.org/10.1101/2021.08.25.457612
Autor:
Stavroula, Petridi, Anne-Claire, Jacomin, Zambarlal, Bhujabal, Terje, Johansen, Ioannis P, Nezis
Publikováno v:
Methods in cell biology. 165
Autophagy has been described as a catabolic process in which cytoplasmic material is being recycled under various conditions of cellular stress, preventing cell damage and promoting cell survival. Drosophila has been demonstrated to provide an excell
Publikováno v:
Methods in Cell Biology ISBN: 9780128244876
Autophagy has been described as a catabolic process in which cytoplasmic material is being recycled under various conditions of cellular stress, preventing cell damage and promoting cell survival. Drosophila has been demonstrated to provide an excell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d918542b128c00337bb8f0b09893800
http://wrap.warwick.ac.uk/143688/7/WRAP-2020.pdf
http://wrap.warwick.ac.uk/143688/7/WRAP-2020.pdf
Publikováno v:
Autophagy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Despite the growing evidence that the macroautophagy/autophagy-related protein LC3 is localized in the nucleus, why and how it is targeted to the nucleus are poorly understood. In our recent study, we found that transcription factor seq (sequoia) int