Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Stavros Zanos"'
Autor:
Federico Ciotti, Robert John, Natalija Katic Secerovic, Noemi Gozzi, Andrea Cimolato, Naveen Jayaprakash, Weiguo Song, Viktor Toth, Theodoros Zanos, Stavros Zanos, Stanisa Raspopovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Bioelectronic therapies modulating the vagus nerve are promising for cardiovascular, inflammatory, and mental disorders. Clinical applications are however limited by side-effects such as breathing obstruction and headache caused by non-speci
Externí odkaz:
https://doaj.org/article/f961fa4d668f430fa89aa693cfe5e62c
Autor:
Stefanos Zafeiropoulos, MD, PhD, Nicholas J. Beccarino, MD, Stavros Stavrakis, MD, PhD, Stavros Zanos, MD, PhD, Raman Mitra, MD, PhD
Publikováno v:
JACC: Case Reports, Vol 29, Iss 13, Pp 102373- (2024)
Cardioneuroablation is a novel approach to treat patients with recurrent vasovagal syncope (VVS), targeting the ganglionated plexi around the atria and thus reducing the vagal input to the heart. This study reports a case of drug-refractory VVS after
Externí odkaz:
https://doaj.org/article/a32675cdf4ca42f0b03aa1ea06eaa0f2
Autor:
Ibrahim T. Mughrabi, Michael Gerber, Naveen Jayaprakash, Santhoshi P. Palandira, Yousef Al-Abed, Timir Datta-Chaudhuri, Corey Smith, Valentin A. Pavlov, Stavros Zanos
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background The noradrenergic innervation of the spleen is implicated in the autonomic control of inflammation and has been the target of neurostimulation therapies for inflammatory diseases. However, there is no real-time marker of its succe
Externí odkaz:
https://doaj.org/article/89e0b92ee1164d0a8b1115da6bbd4daa
Autor:
Eric H. Chang, Arielle H. Gabalski, Tomas S. Huerta, Timir Datta-Chaudhuri, Theodoros P. Zanos, Stavros Zanos, Warren M. Grill, Kevin J. Tracey, Yousef Al-Abed
Publikováno v:
Bioelectronic Medicine, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract The emerging field of bioelectronic medicine (BEM) is poised to make a significant impact on the treatment of several neurological and inflammatory disorders. With several BEM therapies being recently approved for clinical use and others in
Externí odkaz:
https://doaj.org/article/bf9dae8608184cdb9541838584ab39b1
Autor:
Stavros Zanos, Despoina Ntiloudi, John Pellerito, Richard Ramdeo, John Graf, Kirk Wallace, Victoria Cotero, Jeff Ashe, Jessica Moon, Meghan Addorisio, David Shoudy, Thomas R. Coleman, Michael Brines, Chris Puleo, Kevin J. Tracey, Sangeeta S. Chavan
Publikováno v:
Brain Stimulation, Vol 16, Iss 3, Pp 703-711 (2023)
Focused ultrasound stimulation (FUS) activates mechanosensitive ion channels and is emerging as a method of noninvasive neuromodulation. In preclinical studies, FUS of the spleen (sFUS) activates an anti-inflammatory neural pathway which suppresses a
Externí odkaz:
https://doaj.org/article/be0515c41a95436fa5b189fda07edc16
Autor:
Naveen Jayaprakash, Weiguo Song, Viktor Toth, Avantika Vardhan, Todd Levy, Jacquelyn Tomaio, Khaled Qanud, Ibrahim Mughrabi, Yao-Chuan Chang, Moontahinaz Rob, Anna Daytz, Adam Abbas, Zeinab Nassrallah, Bruce T. Volpe, Kevin J. Tracey, Yousef Al-Abed, Timir Datta-Chaudhuri, Larry Miller, Mary F. Barbe, Sunhee C. Lee, Theodoros P. Zanos, Stavros Zanos
Publikováno v:
Brain Stimulation, Vol 16, Iss 2, Pp 484-506 (2023)
Vagal fibers travel inside fascicles and form branches to innervate organs and regulate organ functions. Existing vagus nerve stimulation (VNS) therapies activate vagal fibers non-selectively, often resulting in reduced efficacy and side effects from
Externí odkaz:
https://doaj.org/article/98dc21c6939945af94101697d88b381f
Autor:
Ahmad Altiti, Mingzhu He, Sonya VanPatten, Kai Fan Cheng, Umair Ahmed, Pui Yan Chiu, Ibrahim T. Mughrabi, Bayan Al Jabari, Ronald M. Burch, Kirk R. Manogue, Kevin J. Tracey, Betty Diamond, Christine N. Metz, Huan Yang, LaQueta K. Hudson, Stavros Zanos, Myoungsun Son, Barbara Sherry, Thomas R. Coleman, Yousef Al-Abed
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The rapid protease degradation of peptides is currently limiting their therapeutic utility. Here, the authors report functionalised thiocarbazate scaffolds as precursors of aza-amino acids that can be integrated in peptide sequences, extending their
Externí odkaz:
https://doaj.org/article/a48c24524daa4e5cb8838c0018607cb6
Autor:
Yao-Chuan Chang, Umair Ahmed, Naveen Jayaprakash, Ibrahim Mughrabi, Qihang Lin, Yi-Chen Wu, Michael Gerber, Adam Abbas, Anna Daytz, Arielle H. Gabalski, Jason Ashville, Socrates Dokos, Loren Rieth, Timir Datta-Chaudhuri, Kevin J. Tracey, Tianruo Guo, Yousef Al-Abed, Stavros Zanos
Publikováno v:
Brain Stimulation, Vol 15, Iss 6, Pp 1389-1404 (2022)
Background: Vagal reflexes regulate homeostasis in visceral organs and systems through afferent and efferent neurons and nerve fibers. Small, unmyelinated, C-type afferents comprise over 80% of fibers in the vagus and form the sensory arc of autonomi
Externí odkaz:
https://doaj.org/article/42a0208fdf1541a38a60370b2b0903c8
Autor:
Rishabh C. Choudhary, Umair Ahmed, Muhammad Shoaib, Eric Alper, Abdul Rehman, Junhwan Kim, Koichiro Shinozaki, Bruce T. Volpe, Sangeeta Chavan, Stavros Zanos, Kevin J. Tracey, Lance B. Becker
Publikováno v:
Bioelectronic Medicine, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract Background Vagus nerve stimulation (VNS) has shown therapeutic potential in a variety of different diseases with many ongoing clinical trials. The role of VNS in reducing ischemic injury in the brain requires further evaluation. Cardiac arre
Externí odkaz:
https://doaj.org/article/d4a9a43bf11f4d4fb295592752645278
Autor:
Umair Ahmed, Yao-Chuan Chang, Stefanos Zafeiropoulos, Zeinab Nassrallah, Larry Miller, Stavros Zanos
Publikováno v:
Bioelectronic Medicine, Vol 8, Iss 1, Pp 1-20 (2022)
Abstract The vagus nerve is involved in the autonomic regulation of physiological homeostasis, through vast innervation of cervical, thoracic and abdominal visceral organs. Stimulation of the vagus with bioelectronic devices represents a therapeutic
Externí odkaz:
https://doaj.org/article/86e1257249f84169965900a2097df59c