Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Stavros, Taraviras"'
Autor:
Konstantina Kaplani, Maria-Eleni Lalioti, Styliani Vassalou, Georgia Lokka, Evangelia Parlapani, Georgios Kritikos, Zoi Lygerou, Stavros Taraviras
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 11, Pp 2725-2748 (2024)
Abstract Hydrocephalus is a common neurological condition, characterized by the excessive accumulation of cerebrospinal fluid in the cerebral ventricles. Primary treatments for hydrocephalus mainly involve neurosurgical cerebrospinal fluid diversion,
Externí odkaz:
https://doaj.org/article/555feaa82afb46648bf1dd843b53d7ce
Autor:
Ioannis Angelopoulos, Georgios Gakis, Kyriakos Birmpas, Christina Kyrousi, Evagelia Eva Habeos, Konstantina Kaplani, Zoi Lygerou, Ioannis Habeos, Stavros Taraviras
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The neural stem cell niche is a key regulator participating in the maintenance, regeneration, and repair of the brain. Within the niche neural stem cells (NSC) generate new neurons throughout life, which is important for tissue homeostasis and brain
Externí odkaz:
https://doaj.org/article/8d9eb356380a4ced89c95de4a789f3e0
Autor:
Nikolaos Karantzelis, Michalis Petropoulos, Valeria De Marco, David A. Egan, Alexander Fish, Evangelos Christodoulou, David W. Will, Joe D. Lewis, Anastassis Perrakis, Zoi Lygerou, Stavros Taraviras
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
DNA replication initiation requires the loading of MCM2-7 complexes at the origins of replication during G1. Replication licensing renders chromatin competent for DNA replication and its tight regulation is essential to prevent aberrant DNA replicati
Externí odkaz:
https://doaj.org/article/a12e5a12cb4d47728c4807ff7f7cae4b
Autor:
Konstantinos Ioannidis, Ioannis Angelopoulos, Georgios Gakis, Nikolaos Karantzelis, Georgios A. Spyroulias, Zoi Lygerou, Stavros Taraviras
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Neural stem cells (NSCs) are important constituents of the nervous system, and they become constrained in two specific regions during adulthood: the subventricular zone (SVZ) and the subgranular zone (SGZ) of the dentate gyrus in the hippocampus. The
Externí odkaz:
https://doaj.org/article/664fc3ca99de490f83943881eea1634a
Autor:
Maria Mougkogianni, Argyro Kalogeropoulou, Nickolaos Nikiforos Giakoumakis, Zoi Lygerou, Stavros Taraviras
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100234- (2021)
Summary: The recruitment of the minichromosome maintenance complex (MCM) on DNA replication origins is a critical process for faithful genome duplication termed licensing. Aberrant licensing has been associated with cancer and, recently, with neurode
Externí odkaz:
https://doaj.org/article/a88b52a5c41944fa9f9a9a57d56dce5d
Autor:
Konstantinos Ioannidis, Rodolfos I. Danalatos, Spyridon Champeris Tsaniras, Konstantina Kaplani, Georgia Lokka, Anastasia Kanellou, Dionysios J. Papachristou, Georgios Bokias, Zoi Lygerou, Stavros Taraviras
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Advances in 3D bioprinting have allowed the use of stem cells along with biomaterials and growth factors toward novel tissue engineering approaches. However, the cost of these systems along with their consumables is currently extremely high, limiting
Externí odkaz:
https://doaj.org/article/23333966192a4bc881507e94aabbd0d3
Autor:
Antonia Marazioti, Ioannis Lilis, Malamati Vreka, Hara Apostolopoulou, Argyro Kalogeropoulou, Ioanna Giopanou, Georgia A. Giotopoulou, Anthi C. Krontira, Marianthi Iliopoulou, Nikolaos I. Kanellakis, Theodora Agalioti, Anastasios D. Giannou, Celestial Jones-Paris, Yoichiro Iwakura, Dimitrios Kardamakis, Timothy S. Blackwell, Stavros Taraviras, Magda Spella, Georgios T. Stathopoulos
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Malignant pleural effusion (MPE) is a life-threatening cancer-related disorder. Here, the authors show that KRAS-mutant tumor cells require IKKα, activated via host-provided IL-1β, to promote MPE development and that co-inhibition of both KRAS and
Externí odkaz:
https://doaj.org/article/6a500ee17a8443c4ad3c2fbe668a22da
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-3 (2018)
Abstract Histone variants constitute a fundamental feature of the epigenome. However, their dynamics during normal and challenged DNA replication and their distribution in the three-dimensional space of the nucleus remain poorly characterized. A rece
Externí odkaz:
https://doaj.org/article/f85fcd0df6374665a412fdbc8c0c02ee
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
During the development of the cortex distinct populations of Neural Stem Cells (NSCs) are defined by differences in their cell cycle duration, self-renewal capacity and transcriptional profile. A key difference across the distinct populations of NSCs
Externí odkaz:
https://doaj.org/article/32fd967f76354428b2260e7423cf70e2
Publikováno v:
Trends in Cancer. 8:467-481
Accurate and complete genome duplication is crucial to maintain cell survival and prevent malignant transformation. The Fanconi anemia (FA) pathway has traditionally been associated with the repair of DNA interstrand crosslinks that impede the progre