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pro vyhledávání: '"Stathopoulos, Sofia"'
Autor:
Stathopoulos, Sofia
Includes abstract.
Includes bibliographical references.
This thesis reports the first assessment of OR variation in Bathyergidae, and therefore, the first for a family of subterranean mammals. Using a PCR-sequencing approach, 178 unique OR
Includes bibliographical references.
This thesis reports the first assessment of OR variation in Bathyergidae, and therefore, the first for a family of subterranean mammals. Using a PCR-sequencing approach, 178 unique OR
Externí odkaz:
http://hdl.handle.net/11427/11345
Autor:
Breen, Michael S., Browne, Andrew, Hoffman, Gabriel E., Stathopoulos, Sofia, Brennand, Kristen, Buxbaum, Joseph D., Drapeau, Elodie
Additional file 7: Figure S7. GO semantic similarity and incorporating cell type frequencies for differential expression. GO semantic similarity analysis was applied to examine shared/unique gene content among significantly under-expressed GO terms i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d1c17f7581823fb65502a51be3da92
Autor:
Breen, Michael S., Browne, Andrew, Hoffman, Gabriel E., Stathopoulos, Sofia, Brennand, Kristen, Buxbaum, Joseph D., Drapeau, Elodie
Additional file 13: Figure S13. Data pre-processing using replication hiPSC-neurons. Principal component analyses were performed on RPKM values for (A) all replication set hiPSC-neurons at 6 weeks. Outliers beyond the 95% confidence intervals (black
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516e61eb522e84b863aa07546830fdce
Autor:
Breen, Michael S., Browne, Andrew, Hoffman, Gabriel E., Stathopoulos, Sofia, Brennand, Kristen, Buxbaum, Joseph D., Drapeau, Elodie
Additional file 9: Figure S9. Differential expression in small deletion PMS cases. Genome-wide concordance of log2 fold-changes were examined for small deletion cases using (A) hiPSC-NPCs (4 PMS cases and 4 unaffected siblings, y-axis) and (B) hiPSC-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e488b837e55440573f2278e6d5f773f
Autor:
Breen, Michael S., Browne, Andrew, Hoffman, Gabriel E., Stathopoulos, Sofia, Brennand, Kristen, Buxbaum, Joseph D., Drapeau, Elodie
Additional file 6: Figure S6. Variance explained by SHANK3 deletion size. (A) All genes affected by chr22 deletion in PMS proband from family 6 (4.9Mb deletion) are similarly affected in PMS proband from family 7 (6.9Mb deletion). (B) The linear mixe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37cbea02e123e35e7be1762eaa83cb64
Autor:
Breen, Michael S., Browne, Andrew, Hoffman, Gabriel E., Stathopoulos, Sofia, Brennand, Kristen, Buxbaum, Joseph D., Drapeau, Elodie
Additional file 8: Figure S8. Protein-protein interaction network. Direct protein–protein interaction network of differentially expressed genes identified in (A) hiPSC-NPCs and (B) hiPSC-neurons. Nodes are scaled by their degree of overall connecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f3d7d8a97b7eb84d402399b2cca849
Autor:
Breen, Michael S., Browne, Andrew, Hoffman, Gabriel E., Stathopoulos, Sofia, Brennand, Kristen, Buxbaum, Joseph D., Drapeau, Elodie
Additional file 2: Figure S2. SHANK3 gene expression. (A) SHANK3 gene expression (RPKM) across hiPSC-NPCs and hiPSC-neurons. (B) SHANK3 read coverage in other hiPSC-NPC studies, demonstrating SHANK3 is expressed in hiPSC-NPCs. (C) SHANK3 transcript e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f672c6d915ad5a2182d2abb3571ad4
Autor:
Breen, Michael S., Browne, Andrew, Hoffman, Gabriel E., Stathopoulos, Sofia, Brennand, Kristen, Buxbaum, Joseph D., Drapeau, Elodie
Additional file 4: Figure S4. Cell type deconvolution analysis. Cibersort cell type deconvolution analysis of global gene expression profiles estimated cell frequencies (y-axis) in (A-B) hiPSC-NPCs and (C-D) hiPSC-neurons for four major cell types (x
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b25d801b5dca6bfeec134707e58534
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