Zobrazeno 1 - 10
of 401
pro vyhledávání: '"Stat-1"'
Autor:
Peng Sun, Zhenfeng Li, Zaojun Yan, Zhaofeng Wang, Peng Zheng, Mingliang Wang, Xu Chang, Zihao Liu, Jianxin Zhang, Huiyong Wu, Wenbo Shao, Dewen Xue, Jinming Yu
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Lenvatinib, a multitarget kinase inhibitor, has been proven to be effective in the treatment of advanced hepatocellular carcinoma. It has been previously demonstrated that tumour associated macrophages (TAMs) in tumour tissues can promote HC
Externí odkaz:
https://doaj.org/article/2101331b2a6b4a46b73885fae0b36a05
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractIt has been reported that CDK8 plays a key role in acute myeloid leukaemia. Here, a total of 40 compounds were rational designed and synthesised based on the previous SAR. Among them, compound 12 (3-(3-(furan-3-yl)-1H-pyrrolo[2,3-b]pyridin-5-
Externí odkaz:
https://doaj.org/article/c640f4ab38284665aee61e6a6e5813b7
Akademický článek
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Autor:
Melissa Martins Oliveira, Camila Ramalho Bonturi, Bruno Ramos Salu, Maria Luiza Vilela Oliva, Renato Arruda Mortara, Cristina Mary Orikaza
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Trypanosoma cruzi is the causative protozoan of Chagas’ Disease, a neglected tropical disease that affects 6−7 million people worldwide. Interaction of the parasite with the host immune system is a key factor in disease progression and chronic sy
Externí odkaz:
https://doaj.org/article/9ae4f95b606146b481af18ba58b6241d
Autor:
Elena Candelotti, Roberto De Luca, Roberto Megna, Mariangela Maiolo, Paolo De Vito, Fabio Gionfra, Zulema Antonia Percario, Monica Borgatti, Roberto Gambari, Paul J. Davis, Hung-Yun Lin, Fabio Polticelli, Tiziana Persichini, Marco Colasanti, Elisabetta Affabris, Jens Z. Pedersen, Sandra Incerpi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Interaction between thyroid hormones and the immune system is reported in the literature. Thyroid hormones, thyroxine, T4, but also T3, act non-genomically through mechanisms that involve a plasma membrane receptor αvβ3 integrin, a co-receptor for
Externí odkaz:
https://doaj.org/article/63d4e9c8bcee492a904682a88820f723
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Dana May, Anna Bellizzi, Workineh Kassa, John M. Cipriaso, Maurizio Caocci, Hassen S. Wollebo
Publikováno v:
Viruses, Vol 13, Iss 10, p 1937 (2021)
Polyomavirus JC (JCPyV) causes the demyelinating disease progressive multifocal leukoencephalopathy (PML). JCPyV infection is very common in childhood and, under conditions of severe immunosuppression, JCPyV may reactivate to cause PML. JC viral prot
Externí odkaz:
https://doaj.org/article/93fc35074b7f4e17b9fd7ce3d1153ea0
Autor:
Olivier Escaffre, Terry L. Juelich, Natasha Neef, Shane Massey, Jeanon Smith, Trevor Brasel, Jennifer K. Smith, Birte Kalveram, Lihong Zhang, David Perez, Tetsuro Ikegami, Alexander N. Freiberg, Jason E. Comer
Publikováno v:
Viruses, Vol 13, Iss 7, p 1388 (2021)
Currently there is no FDA-licensed vaccine or therapeutic against Sudan ebolavirus (SUDV) infections. The largest ever reported 2014–2016 West Africa outbreak, as well as the 2021 outbreak in the Democratic Republic of Congo, highlight the critical
Externí odkaz:
https://doaj.org/article/b7e6ee05ac214387bcee0e49e5b0ebf3
Autor:
Sarah McKenna, Taylor Burey, Jeryl Sandoval, Leanna Nguyen, Odalis Castro, Suma Gudipati, Jazmin Gonzalez, Karim C. El Kasmi, Clyde J. Wright
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Sepsis is a major cause of neonatal morbidity and mortality. The current paradigm suggests that neonatal susceptibility to infection is explained by an innate immune response that is functionally immature. Recent studies in adults have questioned a t
Externí odkaz:
https://doaj.org/article/8f86eada4b6b40cbbe58d6e171c6b354