Multiscale Multimodal Investigation of the Intratissural Biodistribution of Iron Nanotherapeutics with Single Cell Resolution Reveals Co-Localization with Endogenous Iron in Splenic Macrophages

Autor: Balfourier, Alice, Tsolaki, Elena, Heeb, Laura, Starsich, Fabian H L, Klose, Daniel, Boss, Andreas, Gupta, Anurag, Gogos, Alexander, Herrmann, Inge K

Publikováno v: Small Methods, 7 (2)

Imaging of iron-based nanoparticles (NPs) remains challenging because of the presence of endogenous iron in tissues that is difficult to distinguish from exogenous iron originating from the NPs. Here, an analytical cascade for characterizing the biod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339980718b0ea7d459e33152f256e3f7
https://hdl.handle.net/20.500.11850/590414

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Catalytic activity imperative for nanoparticle dose enhancement in photon and proton therapy

Autor: Gerken, Lukas R H, Gogos, Alexander, Starsich, Fabian H L, David, Helena, Gerdes, Maren E, Schiefer, Hans, Psoroulas, Serena, Meer, David, Plasswilm, Ludwig, Weber, Damien C, Herrmann, Inge K

Publikováno v: Gerken, Lukas R H; Gogos, Alexander; Starsich, Fabian H L; David, Helena; Gerdes, Maren E; Schiefer, Hans; Psoroulas, Serena; Meer, David; Plasswilm, Ludwig; Weber, Damien C; Herrmann, Inge K (2022). Catalytic activity imperative for nanoparticle dose enhancement in photon and proton therapy. Nature Communications, 13(1), p. 3248. Springer Nature 10.1038/s41467-022-30982-5
Nature Communications, 13 (1)

Nanoparticle-based radioenhancement is a promising strategy for extending the therapeutic ratio of radiotherapy. While (pre)clinical results are encouraging, sound mechanistic understanding of nanoparticle radioenhancement, especially the effects of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e11a99e7c1cca2b14e90d401d3db4f
https://boris.unibe.ch/170510/1/s41467-022-30982-5.pdf

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Smart sealants for prevention and monitoring of gastrointestinal anastomotic leaks using portable smartphone-controlled ultrasound transducers

Autor: Anthis, Alexandre H.C., Abundo, Maria Paulene, Neuer, Anna L., Tsolaki, Elena, Rosendorf, Jachym, Rduch, Thomas, Starsich, Fabian H.L., Liska, Vaclav, Schlegel, Andrea A., Shapiro, Mikhail G., Herrmann, Inge

Publikováno v: bioRxiv

Millions of patients every year undergo gastrointestinal surgery. While often lifesaving, sutured and stapled reconnections leak in around 10% of the cases. Penetration of digestive fluids into the peritoneal cavity may lead to dreadful complications

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______150::5e65b43f5fea4f528844acadc60b7bc6
https://hdl.handle.net/20.500.11850/542521