Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Starlynn C, Clarke"'
Autor:
Harshad S. Ugamraj, Kevin Dang, Laure-Hélène Ouisse, Benjamin Buelow, Eduardo N. Chini, Giulia Castello, James Allison, Starlynn C Clarke, Laura M. Davison, Roland Buelow, Rong Deng, Suhasini Iyer, Ute Schellenberger, Sankar N. Manika, Shipra Bijpuria, Astrid Musnier, Anne Poupon, Maria Cristina Cuturi, Wim van Schooten, Pranjali Dalvi
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Cluster of differentiation 38 (CD38) is an ecto-enzyme expressed primarily on immune cells that metabolizes nicotinamide adenine dinucleotide (NAD+) to adenosine diphosphate ribose or cyclic ADP-ribose and nicotinamide. Other substrates of CD38 inclu
Externí odkaz:
https://doaj.org/article/fdbba7fafcb24832b1853db840f82f25
Autor:
Lawrence Fong, Serena Kwek, Rong Deng, Yuping Li, Kevin Dang, Giulia Castello, Starlynn C Clarke, Aarti Balasubramani, Andrew Boudreau, Laura Davison, Katherine E Harris, Duy Pham, Preethi Sankaran, Harshad S Ugamraj, Alec Starzinski, Suhasini Iyer, Wim van Schooten, Ute Schellenberger, Wenchao Sun, Nathan D Trinklein, Roland Buelow, Ben Buelow, Pranjali Dalvi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Therapeutic options currently available for metastatic castration-resistant prostate cancer (mCRPC) do not extend median overall survival >6 months. Therefore, the development of novel and effective therapies for mCRPC represents an urgent
Externí odkaz:
https://doaj.org/article/b008929f34b84d778350eb4e4a7bcce4
Autor:
Starlynn C. Clarke, Biao Ma, Nathan D. Trinklein, Ute Schellenberger, Michael J. Osborn, Laure-Hélène Ouisse, Andrew Boudreau, Laura M. Davison, Katherine E. Harris, Harshad S. Ugamraj, Aarti Balasubramani, Kevin H. Dang, Brett Jorgensen, Heather Anne N. Ogana, Duy T. Pham, Payal P. Pratap, Preethi Sankaran, Ignacio Anegon, Wim C. van Schooten, Marianne Brüggemann, Roland Buelow, Shelley Force Aldred
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Heavy chain-only antibodies (HCAbs) do not associate with light chains and their VH regions are functional as single domains, forming the smallest active antibody fragment. These VH regions are ideal building blocks for a variety of antibody-based bi
Externí odkaz:
https://doaj.org/article/6a706cdfcb4649ab82279f4b31c5c13b
Autor:
Elaine Lau, George Kwong, Tristan W. Fowler, Bee-Chun Sun, Paul D. Donohoue, Ryan T. Davis, Mara Bryan, Shannon McCawley, Starlynn C. Clarke, Carolyn Williams, Lynda Banh, Matthew Irby, Leslie Edwards, Meghan Storlie, Bryan Kohrs, Graham W.J. Lilley, Stephen C. Smith, Scott Gradia, Chris K. Fuller, Justin Skoble, Elizabeth Garner, Megan van Overbeek, Steven B. Kanner
Publikováno v:
Cytotherapy.
Autor:
Katherine E. Harris, Shelley Force Aldred, Laura M. Davison, Heather Anne N. Ogana, Andrew Boudreau, Marianne Brüggemann, Michael Osborn, Biao Ma, Benjamin Buelow, Starlynn C. Clarke, Kevin H. Dang, Suhasini Iyer, Brett Jorgensen, Duy T. Pham, Payal P. Pratap, Udaya S. Rangaswamy, Ute Schellenberger, Wim C. van Schooten, Harshad S. Ugamraj, Omid Vafa, Roland Buelow, Nathan D. Trinklein
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
We created a novel transgenic rat that expresses human antibodies comprising a diverse repertoire of heavy chains with a single common rearranged kappa light chain (IgKV3-15-JK1). This fixed light chain animal, called OmniFlic, presents a unique syst
Externí odkaz:
https://doaj.org/article/0e55864017b746d182977ff0f5e8bf28
Autor:
Starlynn C Clarke, Phillip A Dumesic, Christina M Homer, Anthony J O'Donoghue, Florencia La Greca, Lenka Pallova, Pavel Majer, Hiten D Madhani, Charles S Craik
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006051 (2016)
The opportunistic fungal pathogen Cryptococcus neoformans is a major cause of mortality in immunocompromised individuals, resulting in more than 600,000 deaths per year. Many human fungal pathogens secrete peptidases that influence virulence, but in
Externí odkaz:
https://doaj.org/article/f632f8bdbdf246f2a8c203655a10e817
Publikováno v:
mBio, Vol 6, Iss 6 (2015)
ABSTRACT Peptide-based pheromones are used throughout the fungal kingdom for coordinating sexual responses between mating partners. Here, we address the properties and function of Bar1, an aspartyl protease that acts as a “barrier” and antagonist
Externí odkaz:
https://doaj.org/article/02af93dcc5074eba9b425b0730e6d660