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Ceramide as an endothelial cell surface receptor and a lung-specific lipid vascular target for circulating ligands.

Autor: Staquicini DI; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., Cardó-Vila M; University of Arizona Cancer Center, University of Arizona, Tucson, AZ 85724.; Department of Otolaryngology-Head and Neck Surgery, University of Arizona, Tucson, AZ 85724., Rotolo JA; Department of Molecular Pharmacology, Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, NY 10021., Staquicini FI; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., Tang FHF; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., Smith TL; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., Ganju A; Department of Molecular Pharmacology, Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, NY 10021., Schiavone C; Department of Medicine, Mathematics in Medicine Program, Houston Methodist Research Institute, Houston, TX 77030., Dogra P; Department of Medicine, Mathematics in Medicine Program, Houston Methodist Research Institute, Houston, TX 77030.; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY 10065., Wang Z; Department of Medicine, Mathematics in Medicine Program, Houston Methodist Research Institute, Houston, TX 77030.; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY 10065.; Neal Cancer Center, Houston Methodist Research Institute, Houston, TX 77030., Cristini V; Department of Medicine, Mathematics in Medicine Program, Houston Methodist Research Institute, Houston, TX 77030.; Neal Cancer Center, Houston Methodist Research Institute, Houston, TX 77030.; Department of Imaging Physics, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030.; Physiology, Biophysics and Systems Biology Program, Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY 10065., Giordano RJ; Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP 05508, Brazil., Ozawa MG; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305., Driessen WHP; David H. Koch Center and Department of Genitourinary Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030., Proneth B; Institute of Metabolism and Cell Death, Helmholtz Zentrum Muenchen, Muenchen, Neuherberg 85764, Germany., Souza GR; David H. Koch Center and Department of Genitourinary Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030., Brinker LM; Department of Chemical and Biological Engineering, Center for Micro-Engineered Materials, University of New Mexico, Albuquerque, NM 87131., Noureddine A; Department of Chemical and Biological Engineering, Center for Micro-Engineered Materials, University of New Mexico, Albuquerque, NM 87131., Snider AJ; Stony Brook Cancer Center, Stony Brook University Hospital and Department of Medicine, Renaissance School of Medicine, Stony Brook University, Brook for Brookhaven, Suffolk County, NY 11794., Canals D; Stony Brook Cancer Center, Stony Brook University Hospital and Department of Medicine, Renaissance School of Medicine, Stony Brook University, Brook for Brookhaven, Suffolk County, NY 11794., Gelovani JG; Office of the Provost, United Arab Emirates University, Al Ain, Abu Dhabi 15551, UAE., Petrache I; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, National Jewish Health, Denver, CO 80206.; Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045., Tuder RM; Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045., Obeid LM; Stony Brook Cancer Center, Stony Brook University Hospital and Department of Medicine, Renaissance School of Medicine, Stony Brook University, Brook for Brookhaven, Suffolk County, NY 11794., Hannun YA; Stony Brook Cancer Center, Stony Brook University Hospital and Department of Medicine, Renaissance School of Medicine, Stony Brook University, Brook for Brookhaven, Suffolk County, NY 11794.; Stony Brook Cancer Center, Stony Brook University Hospital and Departments of Biochemistry and Pathology, Renaissance School of Medicine, Stony Brook University, Brookhaven, NY 11794., Kolesnick RN; Department of Molecular Pharmacology, Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, NY 10021., Brinker CJ; Department of Chemical and Biological Engineering, Center for Micro-Engineered Materials, University of New Mexico, Albuquerque, NM 87131., Pasqualini R; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., Arap W; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Hematology/Oncology, Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ 07103.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Aug 22; Vol. 120 (34), pp. e2220269120. Date of Electronic Publication: 2023 Aug 14.

Design and proof of concept for targeted phage-based COVID-19 vaccination strategies with a streamlined cold-free supply chain.

Autor: Staquicini DI; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., Tang FHF; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., Markosian C; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., Yao VJ; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., Staquicini FI; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., Dodero-Rojas E; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005., Contessoto VG; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005.; Department of Physics, Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University, São José do Rio Preto, SP 15054, Brazil., Davis D; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., O'Brien P; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., Habib N; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., Smith TL; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103., Bruiners N; Public Health Research Institute, Rutgers New Jersey Medical School, Newark, NJ 07103., Sidman RL; Department of Neurology, Harvard Medical School, Boston, MA 02115., Gennaro ML; Public Health Research Institute, Rutgers New Jersey Medical School, Newark, NJ 07103., Lattime EC; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901.; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901., Libutti SK; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901.; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901., Whitford PC; Department of Physics and Center for Theoretical Biological Physics, Northeastern University, Boston, MA 02115., Burley SK; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901.; RCSB Protein Data Bank and Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, NJ 08854.; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854.; RCSB Protein Data Bank, San Diego Supercomputer Center and Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92067., Onuchic JN; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005; jonuchic@rice.edu renata.pasqualini@rutgers.edu wadih.arap@rutgers.edu.; Department of Biosciences, Rice University, Houston, TX 77005.; Department of Chemistry, Rice University, Houston, TX 77005.; Department of Physics and Astronomy, Rice University, Houston, TX 77005., Arap W; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101; jonuchic@rice.edu renata.pasqualini@rutgers.edu wadih.arap@rutgers.edu.; Division of Hematology/Oncology, Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ 07103., Pasqualini R; Rutgers Cancer Institute of New Jersey, Newark, NJ 07101; jonuchic@rice.edu renata.pasqualini@rutgers.edu wadih.arap@rutgers.edu.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jul 27; Vol. 118 (30).

Targeted Phage Display-based Pulmonary Vaccination in Mice and Non-human Primates.

Autor: Staquicini DI; Rutgers Cancer Institute of New Jersey, Newark, NJ 07103, USA.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.; These authors equally contributed to this work., Barbu EM; David H. Koch Center, Department of Genitourinary Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.; These authors equally contributed to this work., Zemans RL; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI 48109, USA., Dray BK; Michale E. Keeling Center for Comparative Medicine and Research, Department of Comparative Medicine, The University of Texas M. D. Anderson Cancer Center, Bastrop, TX 78602, USA.; Current address: Charles River Laboratories, Ashland, OH, USA., Staquicini FI; Rutgers Cancer Institute of New Jersey, Newark, NJ 07103, USA.; Current address: MBrace Therapeutics, Summit, NJ, USA., Dogra P; Mathematics in Medicine Program, Houston Methodist Research Institute, Houston, TX 77030, USA., Cardó-Vila M; The University of Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA.; Department of Otolaryngology - Head & Neck Surgery, University of Arizona College of Medicine, Tucson, AZ 85724, USA.; Department of Cellular and Molecular Medicine, University of Arizona College of Medicine, Tucson, AZ 85724, USA., Miranti CK; The University of Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA.; Department of Cellular and Molecular Medicine, University of Arizona College of Medicine, Tucson, AZ 85724, USA., Baze WB; Michale E. Keeling Center for Comparative Medicine and Research, Department of Comparative Medicine, The University of Texas M. D. Anderson Cancer Center, Bastrop, TX 78602, USA., Villa LL; Cancer Institute of São Paulo, University of São Paulo Medical School, São Paulo, SP 01246, Brazil.; Department of Radiology and Medical Oncology, University of São Paulo Medical School, São Paulo, SP 01246, Brazil., Kalil J; Laboratory of Immunology, Heart Institute, University of São Paulo Medical School, São Paulo, SP 05403, Brazil.; Division of Clinical Immunology and Allergy, Department of Medicine, University of São Paulo Medical School, São Paulo, SP 05403, Brazil., Sharma G; University of New Mexico Comprehensive Cancer Center, Albuquerque, NM 87131, USA.; Division of Molecular Medicine, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA., Prossnitz ER; University of New Mexico Comprehensive Cancer Center, Albuquerque, NM 87131, USA.; Division of Molecular Medicine, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA., Wang Z; Mathematics in Medicine Program, Houston Methodist Research Institute, Houston, TX 77030, USA., Cristini V; Mathematics in Medicine Program, Houston Methodist Research Institute, Houston, TX 77030, USA.; Department of Imaging Physics, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77230, USA.; Department of Nanomedicine, Methodist Hospital Research Institute, Houston, TX 77030, USA., Sidman RL; Department of Neurology, Harvard Medical School, Boston, MA 02115, USA., Berman AR; Division of Pulmonary, Critical Care Medicine, Allergy & Rheumatology, Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ 07103, USA., Panettieri RA Jr; Rutgers Institute for Translational Medicine and Science, New Brunswick, NJ 08901, USA., Tuder RM; Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Pasqualini R; Rutgers Cancer Institute of New Jersey, Newark, NJ 07103, USA.; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.; These authors jointly supervised this work.; Lead contact., Arap W; Rutgers Cancer Institute of New Jersey, Newark, NJ 07103, USA.; Division of Hematology/Oncology, Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.; These authors jointly supervised this work.

Publikováno v: Med (New York, N.Y.) [Med] 2021 Mar 12; Vol. 2 (3), pp. 321-342. Date of Electronic Publication: 2020 Dec 10.

Eph receptors as cancer targets for antibody-based therapy.

Autor: Tang FHF; Rutgers Cancer Institute of New Jersey, Newark, NJ, United States; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ, United States., Davis D; Rutgers Cancer Institute of New Jersey, Newark, NJ, United States; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ, United States., Arap W; Rutgers Cancer Institute of New Jersey, Newark, NJ, United States; Division of Hematology/Oncology, Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ, United States. Electronic address: wadih.arap@rutgers.edu., Pasqualini R; Rutgers Cancer Institute of New Jersey, Newark, NJ, United States; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ, United States. Electronic address: renata.pasqualini@rutgers.edu., Staquicini FI; Rutgers Cancer Institute of New Jersey, Newark, NJ, United States; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ, United States. Electronic address: fernanda.staquicini@rutgers.edu.

Publikováno v: Advances in cancer research [Adv Cancer Res] 2020; Vol. 147, pp. 303-317. Date of Electronic Publication: 2020 Jun 12.