Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Staphylococcus aureus/ drug effects/ genetics"'
Autor:
Oliver T. Carnell, Nikolay Zenkin, William L. Kelley, Bohdan Bilyk, Jeffrey Green, Viralkumar V. Panchal, Simon J. Foster, Jamie K. Hobbs, Joshua A. F. Sutton, Hamed Mosaei, David P. Hornby, Caitlin Griffiths
Publikováno v:
PLoS Pathogens
PLOS Pathogens, Vol. 16, No 7 (2020) P. e1008672
PLoS Pathogens, Vol 16, Iss 7, p e1008672 (2020)
PLOS Pathogens, Vol. 16, No 7 (2020) P. e1008672
PLoS Pathogens, Vol 16, Iss 7, p e1008672 (2020)
Most clinical MRSA (methicillin-resistant S. aureus) isolates exhibit low-level β-lactam resistance (oxacillin MIC 2–4 μg/ml) due to the acquisition of a novel penicillin binding protein (PBP2A), encoded by mecA. However, strains can evolve high-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956b4f17bd86062dc65d2eed9ac057c5
http://europepmc.org/articles/PMC7380596
http://europepmc.org/articles/PMC7380596
Autor:
Adriana Renzoni, Patrice Francois, Jacques Schrenzel, Pierre Vaudaux, Elzbieta Huggler, Christine Barras, Antoinette Monod, William L. Kelley, Daniel Pablo Lew, René Studer
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, Vol. 53, No 3 (2009) pp. 903-911
Antimicrobial Agents and Chemotherapy, Vol. 53, No 3 (2009) pp. 903-911
Endogenous, low-level glycopeptide resistance in Staphylococcus aureus results from multifactorial genetic changes. Comparative genomic hybridization analysis revealed the specific deletion of a 1.8-kb segment encompassing two adjacent open reading f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebe1a2243fc56a97de8db0e3e29342e
http://aac.asm.org/content/53/3/903.long
http://aac.asm.org/content/53/3/903.long
Autor:
Daniel Pablo Lew, Antoine Huyghe, Stéphan Juergen Harbarth, Sasi Dharan, Yvan Charbonnier, Thibaud Koessler, Manuela Bento, Didier Pittet, Gesuele Renzi, Patrice Francois, Jacques Schrenzel
Publikováno v:
Journal of Clinical Microbiology, Vol. 44, No 3 (2006) pp. 1040-1048
Until recently, methicillin-resistant Staphylococcus aureus (MRSA) was considered the prototype of a hospital-acquired bacterial pathogen. However, recent reports have shown that MRSA has now emerged in the community. Characterization of specific mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4586bd65a712ddb3cf67aee82ded3a
https://doi.org/10.1128/jcm.44.3.1040-1048.2006
https://doi.org/10.1128/jcm.44.3.1040-1048.2006
Autor:
Dongmei Li, Daniel Pablo Lew, Manuela Bento, Pierre Vaudaux, Asllan Gjinovci, Jacques Schrenzel
Publikováno v:
Antimicrobial Agents and Chemotherapy, Vol. 49, No 9 (2005) pp. 3789-3793
The therapeutic activity of ceftobiprole medocaril, the water-soluble prodrug of ceftobiprole, was compared to that of vancomycin in a rat tissue cage model of chronic methicillin-resistant Staphylococcus aureus (MRSA) foreign-body infection. The MIC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438825fca2de88bf28933f73edc11d6e
https://doi.org/10.1128/aac.49.9.3789-3793.2005
https://doi.org/10.1128/aac.49.9.3789-3793.2005
Publikováno v:
Scopus-Elsevier
Journal of Antimicrobial Chemotherapy, Vol. 47, No 2 (2001) pp. 163-170
Journal of Antimicrobial Chemotherapy, Vol. 47, No 2 (2001) pp. 163-170
Several reports indicate the emergence of subpopulations resistant to glycopeptides in some clinical isolates of Staphylococcus aureus. While the development of glycopeptide resistance in S. aureus is easily observed in vitro, the in vivo conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bd641451b566c0891b846d643201ff
https://doi.org/10.1093/jac/47.2.163
https://doi.org/10.1093/jac/47.2.163
Autor:
Ambre Jousselin, Pierre Vaudaux, Adriana Renzoni, Antoinette Monod, Christine Barras, Diego O. Andrey, William L. Kelley, Daniel Pablo Lew
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21577 (2011)
PloS one
PLoS ONE
PLOS ONE, Vol. 6, No 6 (2011) P. e21577
PloS One
PloS one
PLoS ONE
PLOS ONE, Vol. 6, No 6 (2011) P. e21577
PloS One
The precise mechanisms leading to the emergence of low-level glycopeptide resistance in Staphylococcus aureus are poorly understood. In this study, we used whole genome deep sequencing to detect differences between two isogenic strains: a parental st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a2d1d85acb0729cfadfdafdb89c261
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21738716/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21738716/?tool=EBI
Autor:
Patrice Francois, Yan Q. Xiong, Jacques Schrenzel, Arnold S. Bayer, Soo-Jin Yang, Andreas Peschel, Paul M. Dunman
Publikováno v:
Antimicrobial Agents and Chemotherapy, Vol. 53, No 6 (2009) pp. 2636-2637
We used a well-characterized isogenic set of clinical bloodstream Staphylococcus aureus strains to study (i) regulation of mprF -mediated phosphatidylglycerol lysinylation in the contexts of in vitro daptomycin (DAP) nonsuceptibility and (ii) the rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e296052a1bea212bf77b5188383e5ee
https://pubmed.ncbi.nlm.nih.gov/19289517
https://pubmed.ncbi.nlm.nih.gov/19289517
Autor:
Hans-Georg Sahl, Vesa P. Kontinen, Patrice Francois, Milla Pietiäinen, Manuela Tangomo, Vera Sass, Hanne-Leena Hyyryläinen, Jacques Schrenzel
Publikováno v:
BMC Genomics, Vol. 10, No 429 (2009) P. 429
BMC Genomics, Vol 10, Iss 1, p 429 (2009)
BMC Genomics
BMC Genomics, Vol 10, Iss 1, p 429 (2009)
BMC Genomics
Background Understanding how pathogens respond to antimicrobial peptides, and how this compares to currently available antibiotics, is crucial for optimizing antimicrobial therapy. Staphylococcus aureus has several known resistance mechanisms against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a536bdb4b4ca903f0b60d854bd4f1352
https://archive-ouverte.unige.ch/unige:4600
https://archive-ouverte.unige.ch/unige:4600
Autor:
Adrien Nicolas Fischer, Catherine G. Zimmermann-Ivol, Patrice Francois, Jacques Schrenzel, Jianru Stahl-Zeng, Jean-Charles Sanchez, Manuela Bento, Alexander Scherl, Daniel Lew, Antoine Huyghe, Pierre Vaudaux, Adriana Renzoni, Pierre-Alain Binz, Alexandre Masselot, Thibaud Koessler, Denis F. Hochstrasser, Alireza Vaezzadeh, Yvan Charbonnier, Jacques Deshusses, Francesca Gallè
Publikováno v:
BMC Genomics, Vol 7, Iss 1, p 296 (2006)
BMC Genomics
BMC Genomics, Vol. 7 (2006) P. 296
BMC Genomics
BMC Genomics, Vol. 7 (2006) P. 296
Background To unravel molecular targets involved in glycopeptide resistance, three isogenic strains of Staphylococcus aureus with different susceptibility levels to vancomycin or teicoplanin were subjected to whole-genome microarray-based transcripti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0b2d0d4e9d74be0c62f4533c0dbd6f
http://www.biomedcentral.com/1471-2164/7/296
http://www.biomedcentral.com/1471-2164/7/296
Autor:
Adriana Renzoni, Patrice Francois, William L. Kelley, Jacques Schrenzel, Daniel Pablo Lew, Dongmei Li, Pierre Vaudaux
Publikováno v:
Antimicrobial Agents and Chemotherapy, Vol. 48, No 8 (2004) pp. 2958-2965
The impact of glycopeptide resistance on the molecular regulation of Staphylococcus aureus virulence and attachment to host tissues is poorly documented. We compared stable teicoplanin-resistant methicillin-resistant S. aureus (MRSA) strain 14-4 with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c693ae056b68df35b84565bc64b41afc
https://pubmed.ncbi.nlm.nih.gov/15273106
https://pubmed.ncbi.nlm.nih.gov/15273106