Discovery of a Series of Potent, Selective, and Orally Bioavailable Nucleoside Inhibitors of CD73 That Demonstrates In Vivo Antitumor Activity.

Autor: Li J; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Chen L; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Billedeau RJ; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Stanton TF; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Chiang JTP; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Lee CC; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Li W; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Steggerda S; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Emberley E; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Gross M; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Bhupathi D; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Che X; Wuxi AppTec, Shanghai 200131, China., Chen J; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Dang R; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Huang T; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Ma Y; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., MacKinnon A; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Makkouk A; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Marguier G; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Neou S; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Sotirovska N; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Spurlock S; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Zhang J; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Zhang W; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., van Zandt M; NEDP, Branford, Connecticut 06405, United States., Yuan L; NEDP, Branford, Connecticut 06405, United States., Savoy J; NEDP, Branford, Connecticut 06405, United States., Parlati F; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States., Sjogren EB; Calithera Biosciences, 343 Oyster Point Boulevard, South San Francisco, California 94080, United States.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2023 Jan 12; Vol. 66 (1), pp. 345-370. Date of Electronic Publication: 2022 Dec 18.

Knowing the risk of SUDEP: two family's perspectives and The Danny Did Foundation.

Autor: Stevenson MJ; Board of Directors, Epilepsy Foundation of Colorado, Parker, Colorado, U.S.A., Stanton TF

Publikováno v: Epilepsia [Epilepsia] 2014 Oct; Vol. 55 (10), pp. 1495-500. Date of Electronic Publication: 2014 Oct 16.