Zobrazeno 1 - 10
of 845
pro vyhledávání: '"Stansfeld, P."'
Autor:
Peter Wotherspoon, Hannah Johnston, David J. Hardy, Rachel Holyfield, Soi Bui, Giedrė Ratkevičiūtė, Pooja Sridhar, Jonathan Colburn, Charlotte B. Wilson, Adam Colyer, Benjamin F. Cooper, Jack A. Bryant, Gareth W. Hughes, Phillip J. Stansfeld, Julien R. C. Bergeron, Timothy J. Knowles
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The Maintenance of Lipid Asymmetry (Mla) pathway is a multicomponent system found in all gram-negative bacteria that contributes to virulence, vesicle blebbing and preservation of the outer membrane barrier function. It acts by removing ecto
Externí odkaz:
https://doaj.org/article/b7c3efd6199f407a8b00be9ac32695d5
Autor:
Annie Bunce, Ladan Hashemi, Charlotte Clark, Stephen Stansfeld, Carrie-Anne Myers, Sally McManus
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Evidence on workplace bullying and harassment (WBH) in the UK has not used probability-sample surveys with robust mental health assessments. This study aimed to profile the prevalence and nature of WBH in England, identify inequal
Externí odkaz:
https://doaj.org/article/c1a9b8e1beff4f479e448bafd0bf2f2d
Autor:
Jan Böhning, Miles Graham, Suzanne C. Letham, Luke K. Davis, Ulrike Schulze, Phillip J. Stansfeld, Robin A. Corey, Philip Pearce, Abul K. Tarafder, Tanmay A. M. Bharat
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Inoviruses are filamentous phages infecting numerous prokaryotic phyla. Inoviruses can self-assemble into mesoscale structures with liquid-crystalline order, termed tactoids, which protect bacterial cells in Pseudomonas aeruginosa biofilms f
Externí odkaz:
https://doaj.org/article/6511d5149f124097b4448d6c2a9651f0
Autor:
T. Bertie Ansell, Wanling Song, Claire E. Coupland, Loic Carrique, Robin A. Corey, Anna L. Duncan, C. Keith Cassidy, Maxwell M. G. Geurts, Tim Rasmussen, Andrew B. Ward, Christian Siebold, Phillip J. Stansfeld, Mark S. P. Sansom
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Cryo-electron microscopy (cryo-EM) enables the determination of membrane protein structures in native-like environments. Characterising how membrane proteins interact with the surrounding membrane lipid environment is assisted by resolution
Externí odkaz:
https://doaj.org/article/cf3afb5f6f044bce9bcb06b11105b64c
LptM promotes oxidative maturation of the lipopolysaccharide translocon by substrate binding mimicry
Autor:
Yiying Yang, Haoxiang Chen, Robin A. Corey, Violette Morales, Yves Quentin, Carine Froment, Anne Caumont-Sarcos, Cécile Albenne, Odile Burlet-Schiltz, David Ranava, Phillip J. Stansfeld, Julien Marcoux, Raffaele Ieva
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Insertion of lipopolysaccharide (LPS) into the bacterial outer membrane (OM) is mediated by a druggable OM translocon consisting of a β-barrel membrane protein, LptD, and a lipoprotein, LptE. The β-barrel assembly machinery (BAM) assembles
Externí odkaz:
https://doaj.org/article/ed9b9dea67df414eaaab40bf034d319b
Autor:
Rie Nygaard, Chris L. B. Graham, Meagan Belcher Dufrisne, Jonathan D. Colburn, Joseph Pepe, Molly A. Hydorn, Silvia Corradi, Chelsea M. Brown, Khuram U. Ashraf, Owen N. Vickery, Nicholas S. Briggs, John J. Deering, Brian Kloss, Bruno Botta, Oliver B. Clarke, Linda Columbus, Jonathan Dworkin, Phillip J. Stansfeld, David I. Roper, Filippo Mancia
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Peptidoglycan (PG) is an essential structural component of the bacterial cell wall that is synthetized during cell division and elongation. PG forms an extracellular polymer crucial for cellular viability, the synthesis of which is the targe
Externí odkaz:
https://doaj.org/article/f8db36713a734cacbd61374a4c829bb4
Autor:
Michael F. Fuss, Jan-Philip Wieferig, Robin A. Corey, Yvonne Hellmich, Igor Tascón, Joana S. Sousa, Phillip J. Stansfeld, Janet Vonck, Inga Hänelt
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Cyclic di-AMP is the only known essential second messenger in bacteria and archaea, regulating different proteins indispensable for numerous physiological processes. In particular, it controls various potassium and osmolyte transporters invo
Externí odkaz:
https://doaj.org/article/d7e604588b594a688deb0ddfbae8a895
Autor:
Jeppe K Sørensen, Jacob Pedersen, Hermann Burr, Anders Holm, Tea Lallukka, Thomas Lund, Maria Melchior, Naja H Rod, Reiner Rugulies, Børge Sivertsen, Stephen Stansfeld, Karl B Christensen, Ida Elisabeth Huitfeldt Madsen
Publikováno v:
Scandinavian Journal of Work, Environment & Health, Vol 49, Iss 4, Pp 249-258 (2023)
OBJECTIVE: Previous literature has established associations between psychosocial working conditions and sickness absence (SA), but only few studies have examined associations among younger employees. This study aimed to investigate associations betwe
Externí odkaz:
https://doaj.org/article/e3d34954e7ec40978d90d9ea16d6e293
Autor:
Georgina Ramsay, Zoë Haime, Nadia E Crellin, Jacki L Stansfeld, Stefan Priebe, Maria Long, Joanna Moncrieff
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Objectives Pre-trial acceptability studies may boost recruitment, especially in trials comparing distinctly different interventions. We evaluated the impact of an acceptability study on recruitment to a randomised trial of antipsychotic redu
Externí odkaz:
https://doaj.org/article/94ef08f47836454db25c2b98ebf4fbf6
Autor:
C. Keith Cassidy, Zhuan Qin, Thomas Frosio, Khoosheh Gosink, Zhengyi Yang, Mark S. P. Sansom, Phillip J. Stansfeld, John S. Parkinson, Peijun Zhang
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Motile bacteria employ conserved chemotaxis networks to detect chemical gradients in their surroundings and effectively regulate their locomotion, enabling the location of essential nutrients and other important biological niches. The sensor
Externí odkaz:
https://doaj.org/article/e150b6dfc911417aa1855dc8eac75765