Výsledky vyhledávání - "Stanley Wolf"

Novel biological interactions influence the persistence potential of invasive mountain pine beetle (Dendroctonus ponderosae) in the Canadian Boreal Forest

Autor: Pokorny, Stanley Wolf

Favorable climatic conditions at historical range boundaries have allowed several insect species with eruptive population dynamics to invade adjacent habitats, sometimes causing severe impacts on forest health. However, the potential for recurrent ou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b78e6f8e9c39835497fa6359e2404a56

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Akademický článek

Preemptive antiviral therapy in lung transplantation from hepatitis C donors results in a rapid and sustained virologic responseCentral MessagePerspective

Autor: Mauricio A. Villavicencio, MD, Selena S. Li, MD, Ann Marie Leifer, NP, Jenna L. Gustafson, RN, Asishana Osho, MD, Stanley Wolfe, MD, Yuval Raz, MD, Jason Griffith, MD, PhD, Isabel Neuringer, MD, Emily Bethea, MD, Thais Gift, RPh, Georgina Waldman, RPh, Todd Astor, MD, Nathaniel B. Langer, MD, Raymond T. Chung, MD

Publikováno v: JTCVS Open, Vol 14, Iss , Pp 602-614 (2023)

Objective: The study objective was to assess the safety and efficacy of a preemptive direct-acting antiviral therapy in lung transplants from hepatitis C virus donors to uninfected recipients. Methods: This study is a prospective, open-label, nonrand

Externí odkaz: https://doaj.org/article/d6522b76f91c4ada96420860c5ffdf0f

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B7.2-Ig fusion proteins enhance IL-4-dependent differentiation of tumor-sensitized CD8+ cytotoxic T lymphocyte precursors

Autor: Hirokazu Nakahara, Hiromi Fujiwara, Yang Bian, Shiro Ono, Kyriaki Dunussi-Joannopoulos, Noritami Takeuchi, Mikihiko Kogo, Stanley Wolf, Shin-ichiro Hiraoka

Publikováno v: International Immunology. 17:1071-1079

The B7/CD28 co-stimulatory pathway plays a critical role in T cell activation and differentiation. Our previous study demonstrated that administration of B7.2-Ig fusion proteins to tumor-bearing mice elicits IL-4-dependent, CD8+ T cell-mediated tumor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc765597063434f39373e8a8668cb4a
https://doi.org/10.1093/intimm/dxh288

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The capacity of the natural ligands for CD28 to drive IL-4 expression in naive and antigen-primed CD4+ and CD8+ T cells

Autor: Jun Shimizu, Michio Tomura, Xuyu Zhou, Yumi Yashiro-Ohtani, Yoshiko Mori, Shiro Ono, Shin-ichiro Hiraoka, Yang Bian, Hiromi Fujiwara, Kyriaki Dunussi-Joannopoulos, Stanley Wolf

Publikováno v: International Immunology. 17:73-83

The B7/CD28 costimulatory pathway plays a critical role in T cell activation including Th1/Th2 differentiation. However, little is known about whether CD28 costimulation favors polarization of either Th1 and Th2 or both. Here, we show a critical role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26786d95b3407dc2589d1078d587c5cf
https://doi.org/10.1093/intimm/dxh188

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Efficacy and Mechanisms of Action of rmB7.2-Ig as an Antitumor Agent in Combination with Adriamycin and Cytoxan Chemotherapy

Autor: Stanley Wolf, Lori L. Hayes, Mary E.P. Goad, Jamie Erickson, Kyriaki Dunussi-Joannopoulos, Huanfang Zhou, Ed Clark, Stuart Friedrich, Anthony Wong, Manuel Sequeira, Ronald C. Li

Publikováno v: Clinical Immunology. 101:303-314

The efficacy of chemotherapy for cancer is often limited by toxicity. Immune approaches to cancer immunotherapy, while promising for specificity and long-term protection, have not typically proven potent enough to generate significant therapeutic res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b7618cd44dc9a50257985ee1af1c20
https://doi.org/10.1006/clim.2001.5123

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B7.1 Is a Quantitatively Stronger Costimulus Than B7.2 in the Activation of Naive CD8+ TCR-Transgenic T Cells

Autor: Patrick E. Fields, Rosalynde J. Finch, Gary S. Gray, Richard Zollner, Jenifer L. Thomas, Knut Sturmhoefel, Kwan Lee, Stanley Wolf, Thomas F. Gajewski, Frank W. Fitch

Publikováno v: The Journal of Immunology. 161:5268-5275

Using a TCR transgenic mouse bred onto a recombinase-activating gene-2-deficient background, we have examined the influence of B7.1 and B7.2 on activation of naive, CD8+ T cells in vitro. We found that B7.1 was a more potent costimulus than B7.2 for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2bafcc10244c14c95a9acd0ad04055dc
https://doi.org/10.4049/jimmunol.161.10.5268

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Systemic administration of rIL-12 induces complete tumor regression and protective immunity: response is correlated with a striking reversal of suppressed IFN-γ production by anti-tumor T cells

Autor: Norihiko Yamamoto, Hiroshi Takenaka, Steven H. Herrmann, Hiromi Fujiwara, Tetsuya Fujii, Michiko Kobayashi, Jian-Ping Zou, Toshiyuki Hamaoka, Stanley Wolf

Publikováno v: International Immunology. 7:1135-1145

Unfractionated spleen cells taken from tumor-bearing mice 2 weeks after tumor implantation contained tumor-primed T cells which produced cytokines including IL-2 and IFN-gamma when cultured in vitro. With progressive tumor growth this initial lymphok

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76e7e483cc5f04edeaa3f36c32c9d33
https://doi.org/10.1093/intimm/7.7.1135

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Interleukin-12 but not interferon-γ production correlates with induction of T helper type-1 phenotype in murine candidiasis

Autor: Antonella Mencacci, Stanley Wolf, Laura Tonnetti, Elio Cenci, Paolo Puccetti, Roberta Spaccapelo, Luigina Romani, Francesco Bistoni

Publikováno v: Scopus-Elsevier

By means of polymerase chain reaction-assisted mRNA amplification, we have monitored message levels of interleukin (IL)-12 in splenic macrophages and of interferon-gamma (IFN-gamma), IL-4, and IL-10 in CD4+ and CD8+ T cells using Candida albicans/hos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9a99a3009d50b65c72de9da7bb2288
https://doi.org/10.1002/eji.1830240419

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Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): cytolytic activity and proliferation of NK cells are differentially regulated by NKSF

Autor: Christopher Donahue, Deborah Young, Michael J. Robertson, Jerome Ritz, Robert J. Soiffer, Stanley Wolf, Thomas J. Manley, Steven H. Herrmann

Publikováno v: The Journal of Experimental Medicine

Natural killer cell stimulatory factor (NKSF) is a 70-kD heterodimeric cytokine that was initially isolated from conditioned medium of human B lymphoblastoid cell lines. The effects of recombinant NKSF on the function of human peripheral blood NK cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8b4319b5325b8eb23bbd49472093fc
http://europepmc.org/articles/PMC2119162

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Induction of tumor regression by administration of B7-Ig fusion proteins: mediation by type 2 CD8+ T cells and dependence on IL-4 production

Autor: Shiro Ono, Mikihiko Kogo, Nobuya Yamaguchi, Noritami Takeuchi, Xuyu Zhou, Shin-ichiro Hiraoka, Takao Mukai, Stanley Wolf, Vincent Ling, Kyriaki Dunussi-Joannopoulos, Hiromi Fujiwara

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 172(3)

CD28 signals contribute to either type 1 or type 2 T cell differentiation. Here, we show that administration of B7.2-Ig fusion proteins to tumor-bearing mice induces tumor regression by promoting the differentiation of antitumor type 2 CD8+ effector

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482123b151d3466ed1051998ca5f56b1
https://pubmed.ncbi.nlm.nih.gov/14734709

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