Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Stanley S Stylli"'
Autor:
Simon Haron, Ethan J Kilmister, Paul F Davis, Stanley S Stylli, Theo Mantamadiotis, Andrew H Kaye, Sean R Hall, Swee T Tan, Agadha C Wickremesekera
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 9, Pp 628-642 (2021)
Despite their differences, central nervous system (CNS) tumors and degenerative diseases share important molecular mechanisms underlying their pathologies, due to their common anatomy. Here we review the role of the renin-angiotensin system (RAS) in
Externí odkaz:
https://doaj.org/article/04816149c3aa4ff098288b3e5db93243
Autor:
Chenkai Ma, Hong P T Nguyen, Rodney B Luwor, Stanley S Stylli, Andrew Gogos, Lucia Paradiso, Andrew H Kaye, Andrew P Morokoff
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0189452 (2018)
Glioma is the most common malignant intracranial tumour. Recently, several publications have suggested that miRNAs can be used as potential diagnostic biomarkers of glioma. Here we performed a meta-analysis to identify the diagnostic accuracy of diff
Externí odkaz:
https://doaj.org/article/1d42c5e38fd649a5870464787d3b1aae
Autor:
David CH Tan, Imogen M Roth, Agadha C Wickremesekera, Paul F Davis, Andrew H Kaye, Theo Mantamadiotis, Stanley S Stylli, Swee T Tan
Publikováno v:
Cells, Vol 8, Iss 11, p 1364 (2019)
Patients with glioblastoma (GB), a highly aggressive brain tumor, have a median survival of 14.6 months following neurosurgical resection and adjuvant chemoradiotherapy. Quiescent GB cancer stem cells (CSCs) invariably cause local recurrence. These G
Externí odkaz:
https://doaj.org/article/2cda8275706a44aa90afc9c8a77dcb8f
Autor:
Samuel S. Widodo, Marija Dinevska, Lucero Cuzcano, Michael Papanicolaou, Thomas R. Cox, Stanley S. Stylli, Theo Mantamadiotis
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 7, Iss , Pp 100096- (2023)
Metastatic cancer is responsible for the overwhelming majority of cancer-related deaths, with metastatic tumors being the most common neoplasms affecting the central nervous system. One of the major factors regulating tumor biology is the tumor micro
Externí odkaz:
https://doaj.org/article/b2b6fab43f1a48828905a3e7969b560a
Autor:
Andrea Kwakowsky, Bhavya Chawdhary, Antonio de Souza, Emily Meyer, Andrew H. Kaye, Colin R. Green, Stanley S. Stylli, Helen Danesh-Meyer
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17454 (2023)
Multiple sclerosis (MS) is a neurodegenerative disease marked by chronic neuroinflammation thought to be mediated by the inflammasome pathway. Connexin 43 (Cx43) hemichannels contribute to the activation of the inflammasome through the release of ade
Externí odkaz:
https://doaj.org/article/2b3851cfeb9c4ffcb3730ef63a5aeaf5
Autor:
Dylan Jones, Clarissa A. Whitehead, Marija Dinevska, Samuel S. Widodo, Liam M. Furst, Andrew P. Morokoff, Andrew H. Kaye, Katharine J. Drummond, Theo Mantamadiotis, Stanley S. Stylli
Publikováno v:
Molecular and Cellular Biochemistry. 478:1251-1267
Glioblastoma (GBM) is the most prevalent primary central nervous system tumour in adults. The lethality of GBM lies in its highly invasive, infiltrative, and neurologically destructive nature resulting in treatment failure, tumour recurrence and deat
Autor:
Clarissa A. Whitehead, Haoyun Fang, Huaqi Su, Andrew P. Morokoff, Andrew H. Kaye, Eric Hanssen, Cameron J. Nowell, Katharine J. Drummond, David W. Greening, Laura J. Vella, Theo Mantamadiotis, Stanley S. Stylli
Publikováno v:
Cellular Oncology.
Purpose The therapeutic efficacy of radiotherapy/temozolomide treatment for glioblastoma (GBM) is limited by the augmented invasiveness mediated by invadopodia activity of surviving GBM cells. As yet, however the underlying mechanisms remain poorly u
Autor:
Yangyi Zhang, Bethany K. Campbell, Stanley S. Stylli, Niall M. Corcoran, Christopher M. Hovens
Publikováno v:
Uro. 2:74-92
Advanced prostate cancers have a poor survival rate and a lack of effective treatment options. In order to broaden the available treatments, immunotherapies have been investigated. These include cancer vaccines, immune checkpoint inhibitors, chimeric
Autor:
Marija Dinevska, Samuel S. Widodo, Liam Furst, Lucero Cuzcano, Yitong Fang, Stefano Mangiola, Paul J. Neeson, Phillip K. Darcy, Robert G. Ramsay, Ryan Hutchinson, Fabienne MacKay, Michael Christie, Stanley S. Stylli, Theo Mantamadiotis
Publikováno v:
Cellular oncology (Dordrecht).
Tumor cells thrive by adapting to the signals in their microenvironment. To adapt, cancer cells activate signaling and transcriptional programs and migrate to establish micro-niches, in response to signals from neighboring cells and non-cellular stro
Publikováno v:
Br J Cancer
The prognosis for patients with glioblastoma (GBM), the most common and malignant type of primary brain tumour, is very poor, despite current standard treatments such as surgery, radiotherapy and chemotherapy. Moreover, the immunosuppressive tumour m