Výsledky vyhledávání - "Stanley R. Ress"

Gene expression profiles of bronchoalveolar cells in pulmonary TB

Autor: Richard Pine, Michael D. Weiden, Stanley R. Ress, Yoshihiko Hoshino, Ilana Belitskaya-Levy, Jeffrey A. Gold, B. Raju, Anna Nolan, William N. Rom, Rod Dawson, Stuart M. Brown, Rany Condos

Publikováno v: Tuberculosis. 88:39-51

The host response to Mycobacterium tuberculosis includes macrophage activation, inflammation with increased immune effector cells, tissue necrosis, and cavity formation, and fibrosis, distortion, and bronchiectasis. To evaluate the molecular basis of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e04695e71d2e2779cb2636dc263fc43
https://doi.org/10.1016/j.tube.2007.07.003

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The Effect of Bacille Calmette‐Guérin Vaccine Strain and Route of Administration on Induced Immune Responses in Vaccinated Infants

Autor: Nazma Mansoor, Rose Ann Murray, E. Jane Hughes, Sebastian Gelderbloem, Gregory D. Hussey, Virginia Davids, Anthony Hawkridge, Willem A. Hanekom, Hoyam Gamieldien, Jorge H. Soler, Stanley R. Ress, Gilla Kaplan

Publikováno v: The Journal of Infectious Diseases. 193:531-536

Vaccination with Mycobacterium bovis bacille Calmette-Guerin (BCG) has variable efficacy in preventing tuberculosis. Both BCG strain and route of administration have been implicated in determining efficacy; however, these variables are not considered

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87df7fd281b62be2f9cc40cf548fead9
https://doi.org/10.1086/499825

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Acquired predisposition to mycobacterial disease due to autoantibodies to IFN-γ

Autor: Robert N. Davidson, Simon J. Waddell, Lynn Semple, Anna Goodsall, Robert J. Wilkinson, Elisabeth H. Schölvinck, Brian J. Sheehan, Katalin A. Wilkinson, Alick C Stephens, Mark P. Nicol, Suzanne T. Anderson, Beate Kampmann, David A. Relman, Cheryl Hemingway, Paul R. Langford, Michael Levin, Stanley R. Ress, Martin L. Hibberd

Publikováno v: Journal of Clinical Investigation. 115:2480-2488

Genetic defects in the IFN-gamma response pathway cause unique susceptibility to intracellular pathogens, particularly mycobacteria, but are rare and do not explain mycobacterial disease in the majority of affected patients. We postulated that acquir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198b06a9382399b90db0e1540b5df231
https://doi.org/10.1172/jci19316

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Investigation of adult immunodeficiency and indications for immunoglobulin replacement therapy

Autor: Stanley R. Ress

Publikováno v: SAMJ: South African Medical Journal, Volume: 104, Issue: 11, Pages: 791-792, Published: NOV 2014

Adults presenting with recurrent infections require an approach that allows exclusion of underlying immunodeficiency. While secondary causes of immunodeficiency are the most common, primary immunodeficiency disease (PID) may present for the first tim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede2898443e8ee501d25032d8e1e46f8
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742014001100031&lng=en&tlng=en

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The human macrophage cell line U937 as anin vitromodel for selective evaluation of mycobacterial antigen-specific cytotoxic T-cell function

Autor: Jo-Ann S. Passmore, P. T. Lukey, Stanley R. Ress

Publikováno v: Immunology. 102:146-156

Despite strong evidence for CD8+ T-cell function in murine mycobacterial infections, their corresponding role in human tuberculosis has proven more difficult to demonstrate. We have evaluated the human macrophage (Mphi) cell line U937 as an in vitro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::037b0e3e2bb623644eff9dd19a92a76b
https://doi.org/10.1046/j.1365-2567.2001.01164.x

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Induction of Granulysin and Perforin Cytolytic Mediator Expression in 10-Week-Old Infants Vaccinated with BCG at Birth

Autor: Gilla Kaplan, Virginia Davids, Willem A. Hanekom, Marcia Watkins, Stanley R. Ress, Patricia L. Semple, Alan M. Krensky

Publikováno v: Clinical and Developmental Immunology, Vol 2011 (2011)
Clinical and Developmental Immunology

Background. While vaccination at birth withMycobacterium bovisBacilli Calmette-Guérin (BCG) protects against severe childhood tuberculosis, there is no consensus as to which components of the BCG-induced immune response mediate this protection. Howe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98ad5108f8f5487034a4709ab4ac44d
https://doaj.org/article/e3d8e923da834182b47d6523e012ee5b

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Immunomodulation with Recombinant Interferon-γ1b in Pulmonary Tuberculosis

Autor: Clint Brauns, Chi-Hong Tseng, Rod Dawson, Maryann L. Huie, William N. Rom, Doris B. Tse, Michael D. Weiden, Eric D. Bateman, Stanley R. Ress, Rany Condos, Yoshihiko Hoshino

Publikováno v: PLoS ONE
PLoS ONE, Vol 4, Iss 9, p e6984 (2009)
PLoS One

BACKGROUND Current treatment regimens for pulmonary tuberculosis require at least 6 months of therapy. Immune adjuvant therapy with recombinant interferon-gamma1b (rIFN-gammab) may reduce pulmonary inflammation and reduce the period of infectivity by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61410aeefae60e689dc35650143bfcd6
http://europepmc.org/articles/PMC2737621

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Rifampin levels, interferon-gamma release and outcome in complicated pulmonary tuberculosis

Autor: Robert J. Wilkinson, Peter I. Folb, Stanley R. Ress, Helen McIlleron, Marcia Watkins

Publikováno v: Tuberculosis (Edinburgh, Scotland). 87(6)

Factors that relate to medium-term outcome in patients with pulmonary tuberculosis (PTB) who have completed the 2-month intensive phase of treatment are incompletely understood. The relationship between in vitro production of interferon-gamma (IFN-ga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a273caa0791cc74e6af5c4e4099cbc9
https://pubmed.ncbi.nlm.nih.gov/17890156

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Dose-dependent immune response to Mycobacterium bovis BCG vaccination in neonates

Autor: Rose Ann Murray, Gilla Kaplan, Ronel Sheperd, Anthony Hawkridge, Gregory D. Hussey, Jorge H. Soler, Stanley R. Ress, Lesley Workman, Sebastian Gelderbloem, Virginia Davids, Willem A. Hanekom

Publikováno v: Clinical and vaccine immunology : CVI. 14(2)

In 10-week-old infants vaccinated at birth with JapaneseMycobacterium bovisBCG, the number of dermal needle penetrations correlated positively with frequency of proliferating CD4+T cells in whole blood following BCG stimulation for 6 days but did not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1ad307e51c66bff38ffa835b0bee03
https://pubmed.ncbi.nlm.nih.gov/17182761

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Novel application of a whole blood intracellular cytokine detection assay to quantitate specific T-cell frequency in field studies

Autor: Stanley R. Ress, Nazma Mansoor, Maushumi Mavinkurve, Mzwandile Sidibana, Patrick A. J. Haslett, Anthony Hawkridge, Sebastian Gelderbloem, Virginia Davids, Hoyam Gamieldien, Marcia Watkins, Megan Mendillo, Willem A. Hanekom, Jane Hughes, Rose Ann Murray, Gilla Kaplan, Gregory D. Hussey

Publikováno v: Journal of immunological methods. 291(1-2)

We optimized a whole blood intracellular cytokine assay to quantitate the frequency of specific CD4+ and CD8+ T cells in small volumes of whole blood from infants from developing countries. The assay is performed in two steps. First, whole blood is s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba1f5064f0eda35cdfb9b19a9644792
https://pubmed.ncbi.nlm.nih.gov/15345316

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