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pro vyhledávání: '"Stanley R. Primmer"'
Publikováno v:
Aging.
Almost since the discovery that mutations in the LMNA gene, encoding the nuclear structure components lamin A and C, lead to Hutchinson-Gilford progeria syndrome, people have speculated that lamins may have a role in normal aging. The most common HPG
Autor:
Yasuhiro Nishiyama, Brian O'Nuallain, Eric L. Brown, Sari Sonoda, Kenji Watanabe, Sudhir Paul, Sarah K. Murphy, Stanley R. Primmer, Stephanie Planque, Mariko Hara, Richard Massey, Yukie Mitsuda
Publikováno v:
Journal of Biological Chemistry. 289:13243-13258
Peptide bond-hydrolyzing catalytic antibodies (catabodies) could degrade toxic proteins, but acquired immunity principles have not provided evidence for beneficial catabodies. Transthyretin (TTR) forms misfolded β-sheet aggregates responsible for ag
Autor:
Stanley R. Primmer
Publikováno v:
Journal of Anti-Aging Medicine. 5:179-201
An animal model for experiments in extending life span is needed that is phylogenetically closer to humans than rodents. Although short-lived species are more convenient for research, microarray an...
Autor:
Sun Valley, Stanley R. Primmer
Publikováno v:
Journal of Anti-Aging Medicine. 3:104-108