Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Stanley Meizel"'
Publikováno v:
Biology of Reproduction. 73:807-814
In this study we investigate the role of the CHRNA7 subunit (also known as the alpha7 subunit) of the nicotinic acetylcholine receptor in mouse sperm function. We confirm by reverse-transcription-polymerase chain reaction the expression in adult mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0511b8e62405db3849bdecf4171fa7d1
https://doi.org/10.1095/biolreprod.105.042184
https://doi.org/10.1095/biolreprod.105.042184
Autor:
Stanley Meizel, Priyadarsini Kumar
Publikováno v:
Journal of Biological Chemistry. 280:25928-25935
We demonstrated previously the involvement of a nicotinic acetylcholine receptor containing an alpha7 subunit in the human sperm acrosome reaction (a modified exocytotic event essential to fertilization). Here we report the presence in human sperm of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a15329b3520e3cf481725f694a2e381
https://doi.org/10.1074/jbc.m502435200
https://doi.org/10.1074/jbc.m502435200
Autor:
Jung-Ho Son, Stanley Meizel
Publikováno v:
Molecular Reproduction and Development. 72:250-258
Two sperm neurotransmitter receptor/channels, the glycine receptor (GlyR) and a nicotinic acetylcholine receptor containing an alpha7 subunit (alpha7nAChR) were previously shown to be important to the mouse acrosome reaction (AR) initiated by solubil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eed7eaf73b4acc1287409b464c1514d
https://doi.org/10.1002/mrd.20336
https://doi.org/10.1002/mrd.20336
Autor:
Jung-Ho Son, Stanley Meizel
Publikováno v:
Biology of Reproduction. 68:1348-1353
The mammalian sperm acrosome reaction (AR) is essential to fertilization and is believed to be initiated in vivo by ZP3, a glycoprotein component of the egg zona pellucida (ZP). Recently, we reported the results of antagonist studies suggesting that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2373b5cc9cf0bac447e032bc2c73bd3
https://doi.org/10.1095/biolreprod.102.011163
https://doi.org/10.1095/biolreprod.102.011163
Publikováno v:
Biology of Reproduction. 66:91-97
Previously, we have demonstrated an essential role for the neuronal glycine receptor (GlyR) in the acrosome reaction (AR) of mouse and porcine sperm initiated by the egg zona pellucida (ZP). In the present study, we have demonstrated presence of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b36dec7015538d1a12f37f6b77ff847
https://doi.org/10.1095/biolreprod66.1.91
https://doi.org/10.1095/biolreprod66.1.91
Publikováno v:
Biology of Reproduction. 62:811-820
The signal transduction pathways involved in the progesterone (P(4))-initiated mammalian sperm acrosome reaction (AR) are not fully understood. To investigate the role of the protein kinase A (PKA) pathway in the P(4)-initiated AR, we probed this pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::906ad46bc5e1dcbdf0ca51d3d34c4c57
https://doi.org/10.1095/biolreprod62.3.811
https://doi.org/10.1095/biolreprod62.3.811
Publikováno v:
Molecular Reproduction and Development. 58:205-215
Recent reports have provided evidence for the presence of amino acid neurotransmitter receptor/chloride channels in human and porcine spermatozoa and their involvement in the acrosome reaction (AR). In this work we investigated whether a glycine rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::391c46f9faff3aea46e89ba273fda8fa
https://doi.org/10.1002/1098-2795(200102)58:2<205::aid-mrd10>3.0.co
https://doi.org/10.1002/1098-2795(200102)58:2<205::aid-mrd10>3.0.co
Publikováno v:
Molecular and Cellular Endocrinology. 158:187-193
Antisera against a porcine liver endomembrane progesterone (P4)-binding protein inhibited the P4-initiated acrosome reaction (AR) but not the ionomycin-initiated AR of human sperm. Indirect immunofluorescence studies detected antigen in the sperm hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e45f704c0d1899a6fde96cf07018b1
https://doi.org/10.1016/s0303-7207(99)00173-2
https://doi.org/10.1016/s0303-7207(99)00173-2
Autor:
Manuel A. Garcia, Stanley Meizel
Publikováno v:
Molecular Reproduction and Development. 52:189-195
We previously demonstrated that the progesterone- (P) initiated human sperm acrosome reaction (AR) was dependent on the presence of extracellular Na+ (Na+o). Moreover, Na+o depletion resulted in a decreased cytosolic pH (pHi), suggesting involvement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78a739279bf0f7cdd82d700c4b6c5131
https://doi.org/10.1002/(sici)1098-2795(199902)52:2<189::aid-mrd10>3.0.co
https://doi.org/10.1002/(sici)1098-2795(199902)52:2<189::aid-mrd10>3.0.co
Autor:
Manuel A. Garcia, Stanley Meizel
Publikováno v:
Biology of Reproduction. 60:102-109
The mechanisms of the progesterone (P4)-activated Ca21 influx and the relationship between the intracellular free Ca21 concentration ([Ca21]i) and the acrosome reaction (AR) were investigated in this study. We compared the [Ca21]i of uncapacitated an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b77adecec880e79992b04a749472b12a
https://doi.org/10.1095/biolreprod60.1.102
https://doi.org/10.1095/biolreprod60.1.102