Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Stanley M Belkowski"'
Autor:
Carl L Manthey, Beverley A Moore, Yanqing Chen, Matthew J Loza, Xiang Yao, Hao Liu, Stanley M Belkowski, Holly Raymond-Parks, Paul J Dunford, Francisco Leon, Jennifer E Towne, Scott E Plevy
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0223918 (2019)
BACKGROUND & AIMS:Originally believed to be primarily a disorder of T-cell signaling, evidence shows that macrophage-lineage cells also contribute to the pathogenesis of Crohn's disease (CD). Colony stimulating factor-1 (CSF-1) is a key regulator of
Externí odkaz:
https://doaj.org/article/accefd4db87e43df909fc191a4931e30
Autor:
Jennifer E. Towne, Beverley A. Moore, Stanley M. Belkowski, Paul J. Dunford, S Plevy, Francisco Leon, Yanqing Chen, Xiang Yao, Matthew J. Loza, Hao Liu, Holly Raymond-Parks, Carl L. Manthey
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0223918 (2019)
PLoS ONE
PLoS ONE
Background & aims Originally believed to be primarily a disorder of T-cell signaling, evidence shows that macrophage-lineage cells also contribute to the pathogenesis of Crohn's disease (CD). Colony stimulating factor-1 (CSF-1) is a key regulator of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ba66ea193b02248c5ea76d922812af
https://doaj.org/article/accefd4db87e43df909fc191a4931e30
https://doaj.org/article/accefd4db87e43df909fc191a4931e30
Autor:
Robert Gordon, Brad H. Rovin, Benjamin Hsu, Cynthia Aranow, Ronald F van Vollenhoven, Yanli Zhuang, Stanley M. Belkowski, Carrie Wagner
Publikováno v:
Arthritis & Rheumatology. 68:2174-2183
Objective To assess the efficacy and safety of sirukumab, an anti-interleukin-6 monoclonal antibody, for the treatment of patients with active lupus nephritis (LN). Methods Patients with class III or class IV LN (as determined by renal biopsy within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7539873c40c38bd14d4fb5fb1bee4314
https://doi.org/10.1002/art.39722
https://doi.org/10.1002/art.39722
Autor:
J. D. Boot, L. De Garavilla, Deborah A. Polkovitch, A. Batheja, Zuzana Diamant, Meghan Towers, Michael R. D'Andrea, Stanley M. Belkowski, M. A. Mascelli, Brenda M. Hertzog
Publikováno v:
Clinical & Experimental Allergy. 39:1179-1186
Summary Background Secretory leucocyte protease inhibitor (SLPI), which is present in many physiological fluids including saliva, sputum and nasal discharge, is the most effective inhibitor of chymase. Previously, we demonstrated that chymase is able
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd256042e77f094b50d6067348a3707
https://doi.org/10.1111/j.1365-2222.2009.03247.x
https://doi.org/10.1111/j.1365-2222.2009.03247.x
Autor:
Andrew D. Mahan, Stanley M. Belkowski, Lawrence de Garavilla, Jukka Kervinen, John A. Masucci, Matthew Olson, Michael R. D'Andrea
Publikováno v:
bchm. 389:1219-1224
Secretory leukocyte protease inhibitor (SLPI) is a protease inhibitor of the whey acidic protein-like family inhibiting chymase, chymotrypsin, elastase, proteinase 3, cathepsin G and tryptase. Performing in vitro enzymatic assays using both Western b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e99c480036f6d9e05684563d4aa594d
https://doi.org/10.1515/bc.2008.138
https://doi.org/10.1515/bc.2008.138
Autor:
Michael Naso, Bailin Liang, Don E. Griswold, Danielle Lawrence, Lillian Shahied-Arruda, Michael R. D'Andrea, Xiao-Yu Song, Stanley M. Belkowski, Conway C. Huang, Ray Sweet, Bernard Amegadzie, Debbie A. Polkovitch
Publikováno v:
Journal of Investigative Dermatology. 127(7):1622-1631
Studies performed to discover genes overexpressed in inflammatory diseases identified dermokine as being upregulated in such disease conditions. Dermokine is a gene that was first observed as expressed in the differentiated layers of skin. Its two ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95fa874ce3459e0d9cd2e43b2d467ec
Autor:
James M. Dixon, Mariusz Lubomirski, Michael R. D'Andrea, Javier Cabrera, Dhammika Amaratunga, Stanley M. Belkowski
Publikováno v:
Journal of Computational Biology. 14:350-359
MOTIVATION DNA microarrays are a well-known and established technology in biological and pharmaceutical research providing a wealth of information essential for understanding biological processes and aiding drug development. Protein microarrays are q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdb24fe54561686812332c61cd120ac
https://doi.org/10.1089/cmb.2006.0116
https://doi.org/10.1089/cmb.2006.0116
Autor:
Mark C. Genovese, Andrew Greenspan, Tingting Ge, Stanley M. Belkowski, Carl L. Manthey, Xiaoyu David Yan, Carol F. Franks, Tara Masterson, Elizabeth C. Hsia, Robin L. Thurmond, Caly Chien
Publikováno v:
The Journal of rheumatology. 42(10)
Objective.To assess the efficacy and safety of JNJ-40346527, a selective inhibitor of colony-stimulating factor-1 (CSF-1) receptor kinase that acts to inhibit macrophage survival, proliferation, and differentiation in patients with active rheumatoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61847a4f61e2f79fe1cb7c7786175a0e
https://pubmed.ncbi.nlm.nih.gov/26233509
https://pubmed.ncbi.nlm.nih.gov/26233509
Autor:
John P. Dahl, Yanming Du, Allen B. Reitz, Zhao Boyu, Christopher J. Creighton, Stanley M. Belkowski, Diane A. Gauthier, Zhengyin Yan
Publikováno v:
Bioorganic & Medicinal Chemistry. 13:5936-5948
The enediyne moiety is a versatile functional group found in natural anticancer and anti-infective agents, undergoing the Bergman cyclization reaction to afford a diradical which cleaves double-stranded DNA. We have incorporated the enediyne group in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4176131639510ed34f314cfe7172f84
https://doi.org/10.1016/j.bmc.2005.07.016
https://doi.org/10.1016/j.bmc.2005.07.016
Autor:
Michael R. D'Andrea, Deborah A. Polkovitch, Christopher R. Van Besien, Raymond W. Colburn, Dennis J. Stone, Stanley M. Belkowski, Patricia Andrade-Gordon
Publikováno v:
Clinical Proteomics. 1:249-258
The use of proteomic analysis to discover proteins (previously identified or unknown) in a tissue sample is a valuable tool. However, there is a limit to the extent one can validate a discovery with any single technology. In an effort to obviate this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a17f781e3037fb5b835feb3c2b8617
https://doi.org/10.1385/cp:1:3-4:249
https://doi.org/10.1385/cp:1:3-4:249