Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Stanley J Stachelek"'
Autor:
Ivan S. Alferiev, Bahman Hooshdaran, Benjamin B. Pressly, Philip W. Zoltick, Stanley J. Stachelek, Michael Chorny, Robert J. Levy, Ilia Fishbein
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Impaired endothelialization of endovascular stents has been established as a major cause of in-stent restenosis and late stent thrombosis. Attempts to enhance endothelialization of inner stent surfaces by pre-seeding the stents with endothel
Externí odkaz:
https://doaj.org/article/444eb31192e64188aa9073126ce3c2d6
Autor:
Ilia Fishbein, Vaishali V Inamdar, Ivan S Alferiev, George Bratinov, Menekhem M. Zviman, Anna Yekhilevsky, Chandrasekaran Nagaswami, Kristin L. Gardiner, Robert J Levy, Stanley J Stachelek
BackgroundHypercholesterolemia (HC) has previously been shown to augment restenotic response in several animal models and humans. However, the mechanistic aspects of in-stent restenosis (ISR) on a hypercholesterolemic background, including potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1020134749a03e3614d55f9fbbf8a369
https://doi.org/10.1101/2023.02.27.530304
https://doi.org/10.1101/2023.02.27.530304
Autor:
Estibaliz Castillero, Emmett Fitzpatrick, Samuel J. Keeney, Alex M. D’Angelo, Benjamin B. Pressly, Michael T. Simpson, Mangesh Kurade, W. Clinton Erwin, Vivian Moreno, Chiara Camillo, Halley J. Shukla, Vaishali V. Inamdar, Arbi Aghali, Juan B. Grau, Elisa Salvati, Itzhak Nissim, Lubica Rauova, Mark A. Oyama, Stanley J. Stachelek, Chase Brown, Abba M. Krieger, Robert J. Levy, Giovanni Ferrari
Publikováno v:
Sci Transl Med
Degenerative mitral valve (MV) regurgitation (MR) is a highly prevalent heart disease that requires surgery in severe cases. Here, we show that a decrease in the activity of the serotonin transporter (SERT) accelerates MV remodeling and progression t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b905f7779efd561ae31c4dfab90771f
https://europepmc.org/articles/PMC9896655/
https://europepmc.org/articles/PMC9896655/
Publikováno v:
Polymers, Vol 6, Iss 10, Pp 2526-2551 (2014)
Tissue contacting surfaces of medical devices initiate a host inflammatory response, characterized by adsorption of blood proteins and inflammatory cells triggering the release of cytokines, reactive oxygen species (ROS) and reactive nitrogen species
Externí odkaz:
https://doaj.org/article/34c815baeaaf4dfc8bbabfcd08399d52
Autor:
Andrey Zakharchenko, Yingfei Xue, Samuel Keeney, Christopher A. Rock, Ivan S. Alferiev, Stanley J. Stachelek, Hajime Takano, Tina Thomas, Chandrasekaran Nagaswami, Abba M. Krieger, Michael Chorny, Giovanni Ferrari, Robert J. Levy
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Bioprosthetic heart valves (BHV) fabricated from glutaraldehyde-fixed heterograft tissue, such as bovine pericardium (BP), are widely used for treating heart valve disease, a group of disorders that affects millions. Structural valve degeneration (SV
Autor:
Andrey Zakharchenko, Samuel Keeney, Ivan S Alferiev, Michael Chorny, Yingfei Xue, Hajime Takano, Stanley J Stachelek, Giovanni Ferrari, Robert LEVY
Publikováno v:
Circulation. 144
Introduction: Bioprosthetic heart valves (BHV) fabricated from glutaraldehyde treated bovine pericardium (BP) are widely used to treat heart valve disease. BHV dysfunction from structural valve degeneration (SVD) develops over time, often necessitati
Autor:
Vaishali Inamdar, Menekhem Zviman, George Bratinov, Emmett Fitzpatrick, Kristin Gardiner, Robert Levy, Stanley J Stachelek, Ilia Fishbein
Publikováno v:
Circulation. 144
Background: Inflammatory mechanisms, which can be affected by altered metabolic profiles such as hypercholesterolemia (HC), contribute to the pathophysiology of in-stent restenosis (ISR). CD47 is a transmembrane protein that is known to inhibit immun
Autor:
Vaishali Inamdar, Menekhem Zviman, George Bratinov, Emmett o Fitzpatrick, Kristin Gardiner, Ivan S Alferiev, Robert J Levy, Stanley J Stachelek, Ilia Fishbein
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Background: Hypercholesterolemia (HC) has previously been shown to augment restenotic response in several animal models. However, the mechanistic aspects of in-stent restenosis (ISR) on an HC background are not fully understood. Methods: HC was induc
Autor:
Robert J. Levy, Ivan S. Alferiev, Emmett Fitzpatrick, Stanley J. Stachelek, Vaishali V. Inamdar, Ilia Fishbein
Publikováno v:
J Vis Exp
The key complications associated with bare metal stents and drug eluting stents are in-stent restenosis and late stent thrombosis, respectively. Thus, improving the biocompatibility of metal stents remains a significant challenge. The goal of this pr
Autor:
Ilia Fishbein, Stanley J. Stachelek, Robert J. Levy, Ivan S. Alferiev, Emmett G. Fitzpatrick, Vaishali V. Inamdar
Publikováno v:
Journal of Visualized Experiments.