Zobrazeno 1 - 10
of 527
pro vyhledávání: '"Stanley J, Watson"'
Autor:
Megan H. Hagenauer, Yusra Sannah, Elaine K. Hebda-Bauer, Cosette Rhoads, Angela M. O'Connor, Elizabeth Flandreau, Stanley J. Watson, Jr., Huda Akil
Publikováno v:
MethodsX, Vol 13, Iss , Pp 102788- (2024)
Transcriptional profiling has become a common tool for investigating the nervous system. During analysis, differential expression results are often compared to functional ontology databases, which contain curated gene sets representing well-studied p
Externí odkaz:
https://doaj.org/article/3c68a17835364432afad77bbd564c564
Autor:
Angela May O'Connor, Megan Hastings Hagenauer, Liam Cannon Thew Forrester, Pamela M. Maras, Keiko Arakawa, Elaine K. Hebda-Bauer, Huzefa Khalil, Evelyn R. Richardson, Farizah I. Rob, Yusra Sannah, Stanley J. Watson, Jr., Huda Akil
Publikováno v:
Neurobiology of Stress, Vol 31, Iss , Pp 100651- (2024)
Stress is a major influence on mental health status; the ways that individuals respond to or copes with stressors determine whether they are negatively affected in the future. Stress responses are established by an interplay between genetics, environ
Externí odkaz:
https://doaj.org/article/e85cafcf63ef498da4d0654c83edcf52
Autor:
Adriana M. Medina, Megan Hastings Hagenauer, David M. Krolewski, Evan Hughes, Liam Cannon Thew Forrester, David M. Walsh, Maria Waselus, Evelyn Richardson, Cortney A. Turner, P. Adolfo Sequeira, Preston M. Cartagena, Robert C. Thompson, Marquis P. Vawter, Blynn G. Bunney, Richard M. Myers, Jack D. Barchas, Francis S. Lee, Alan F. Schatzberg, William E. Bunney, Huda Akil, Stanley J. Watson
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The frontal pole (Brodmann area 10, BA10) is the largest cytoarchitectonic region of the human cortex, performing complex integrative functions. BA10 undergoes intensive adolescent grey matter pruning prior to the age of onset for bipolar di
Externí odkaz:
https://doaj.org/article/ecdaa6095ceb4f37b0d1e6facf90baf0
Autor:
Qiang Wei, Vivek Kumar, Shannon Moore, Fei Li, Geoffrey G. Murphy, Stanley J. Watson, Huda Akil
Publikováno v:
Neurobiology of Stress, Vol 27, Iss , Pp 100581- (2023)
Emotions are characterized not only by their valence but also by whether they are stable or labile. Yet, we do not understand the molecular or circuit mechanisms that control the dynamic nature of emotional responses. We have shown that glucocorticoi
Externí odkaz:
https://doaj.org/article/5215fbb9a2754ba6837f91094ae767d0
Autor:
Sujan C. Das, Brooke E. Hjelm, Brandi L. Rollins, Adolfo Sequeira, Ling Morgan, Audrey A. Omidsalar, Alan F. Schatzberg, Jack D. Barchas, Francis S. Lee, Richard M. Myers, Stanley J. Watson, Huda Akil, William E. Bunney, Marquis P. Vawter
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Mitochondrial dysfunction is a neurobiological phenomenon implicated in the pathophysiology of schizophrenia and bipolar disorder that can synergistically affect synaptic neurotransmission. We hypothesized that schizophrenia and bipolar diso
Externí odkaz:
https://doaj.org/article/6f2dcb64f3264a568f9d012a75e13127
Autor:
Firoza Mamdani, Matthieu D. Weber, Blynn Bunney, Kathleen Burke, Preston Cartagena, David Walsh, Francis S. Lee, Jack Barchas, Alan F. Schatzberg, Richard M. Myers, Stanley J. Watson, Huda Akil, Marquis P. Vawter, William E. Bunney, Adolfo Sequeira
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Suicides have increased to over 48,000 deaths yearly in the United States. Major depressive disorder (MDD) is the most common diagnosis among suicides, and identifying those at the highest risk for suicide is a pressing challenge. The object
Externí odkaz:
https://doaj.org/article/14687cc533e84d7586bd3f5377770ca1
Autor:
Pamela M. Maras, Elaine K. Hebda-Bauer, Megan H. Hagenauer, Kathryn L. Hilde, Peter Blandino, Stanley J. Watson, Huda Akil
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Microglia play critical roles in healthy brain development and function, as well as the neuropathology underlying a range of brain diseases. Despite evidence for a role of microglia in affective regulation and mood disorders, little is known
Externí odkaz:
https://doaj.org/article/519a832fa92a4f8cb02453e2bd418be8
Autor:
Apurva S. Chitre, Elaine K. Hebda-Bauer, Peter Blandino, Hannah Bimschleger, Khai-Minh Nguyen, Pamela Maras, Fei Li, A. Bilge Ozel, Yanchao Pan, Oksana Polesskaya, Riyan Cheng, Shelly B. Flagel, Stanley J. Watson, Jun Li, Huda Akil, Abraham A. Palmer
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Common genetic factors likely contribute to multiple psychiatric diseases including mood and substance use disorders. Certain stable, heritable traits reflecting temperament, termed externalizing or internalizing, play a large role in modulating vuln
Externí odkaz:
https://doaj.org/article/b0175e27439b4411910c8a5f75b7f566
Autor:
Aram Parsegian, M. Julia García-Fuster, Elaine Hebda-Bauer, Stanley J. Watson, Shelly B. Flagel, Huda Akil
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Adolescent drug use reliably predicts increased addiction liability in adulthood, but not all individuals are equally impacted. To explore the biological bases of this differential reactivity to early life drug experience, we used a genetic rat model
Externí odkaz:
https://doaj.org/article/4fb0b1fc3c324177a44c15ff262798f9
Autor:
Dalia Murra, Kathryn L. Hilde, Anne Fitzpatrick, Pamela M. Maras, Stanley J. Watson, ., Huda Akil
Publikováno v:
Neurobiology of Stress, Vol 17, Iss , Pp 100437- (2022)
Evaluating and coping with stressful social events as they unfold is a critical strategy in overcoming them without long-lasting detrimental effects. Individuals display a wide range of responses to stress, which can manifest in a variety of outcomes
Externí odkaz:
https://doaj.org/article/c0a4655ad99142668fef1666c954e320