Zobrazeno 1 - 10
of 756
pro vyhledávání: '"Stanley I, Rapoport"'
Autor:
Shaowei Wang, Boyang Li, Victoria Solomon, Alfred Fonteh, Stanley I. Rapoport, David A. Bennett, Zoe Arvanitakis, Helena C. Chui, Patrick M. Sullivan, Hussein N. Yassine
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-21 (2022)
Abstract Background Apolipoprotein E4 (APOE4) is associated with a greater response to neuroinflammation and the risk of developing late-onset Alzheimer’s disease (AD), but the mechanisms for this association are not clear. The activation of calciu
Externí odkaz:
https://doaj.org/article/9b6fcfbf82ae45668070da91de7eda75
Autor:
Shaowei Wang, Boyang Li, Victoria Solomon, Alfred Fonteh, Stanley I. Rapoport, David A. Bennett, Zoe Arvanitakis, Helena C. Chui, Carol Miller, Patrick M. Sullivan, Hoau-Yan Wang, Hussein N. Yassine
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-18 (2021)
Abstract Background Apolipoprotein E4 (APOE4) is associated with a greater response to neuroinflammation and the risk of developing late-onset Alzheimer’s disease (AD), but the mechanisms for this association are not clear. The activation of calciu
Externí odkaz:
https://doaj.org/article/754e453573674c8fbaddf6c526d4ec90
Autor:
Shaowei Wang, Boyang Li, Victoria Solomon, Alfred Fonteh, Stanley I. Rapoport, David A. Bennett, Zoe Arvanitakis, Helena C. Chui, Carol Miller, Patrick M. Sullivan, Hoau-Yan Wang, Hussein N. Yassine
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-1 (2022)
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13024-021-00438-3.
Externí odkaz:
https://doaj.org/article/308e3d75b842470bb5c9e329f202d108
Autor:
Paba M. De Alwis, Bryan R. Smith, Tianxia Wu, Cristah Artrip, Sally Steinbach, Caryn Morse, Chuen-Yen Lau, Stanley I. Rapoport, Joseph Snow, Edmund Tramont, Daniel S. Reich, Govind Nair, Avindra Nath
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Objective: To characterize cerebral arterial remodeling in HIV-infected (HIV+) individuals in-vivo, and to study its clinical and immunological associations.Methods: T2*-weighted magnetic resonance imagining sequences was used to determine cross-sect
Externí odkaz:
https://doaj.org/article/4dacd43d8a654bf5b195ab108a0bab6d
Autor:
Juno, Van Valkenburgh, Marlon Vincent V, Duro, Erica, Burnham, Quan, Chen, Shaowei, Wang, Jenny, Tran, Bilal E, Kerman, Sung Hee, Hwang, Xiaodan, Liu, Naomi S, Sta Maria, Francesca, Zanderigo, Etienne, Croteau, Stanley I, Rapoport, Stephen C, Cunnane, Russell E, Jacobs, Hussein N, Yassine, Kai, Chen
Publikováno v:
Prostaglandins, leukotrienes, and essential fatty acids. 186
Dysreglulated brain arachidonic acid (AA) metabolism is involved in chronic inflammation and is influenced by apolipoprotein E4 (APOE4) genotype, the strongest genetic risk factor of late-onset Alzheimer's disease (AD). Visualization of AA uptake and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7caae59332bd2e29949d9c98f82cba20
https://pubmed.ncbi.nlm.nih.gov/36341886
https://pubmed.ncbi.nlm.nih.gov/36341886
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164326 (2016)
Polyunsaturated fatty acyl (PUFA) chains in both the ω3 and ω6 series are essential for normal animal brain development, and cannot be interconverted to compensate for a dietary deficiency of one or the other. Paradoxically, a dietary ω3-PUFA defi
Externí odkaz:
https://doaj.org/article/b32a00ab7ca348199c4b9cbfe012f5e6
Imaging decreased brain docosahexaenoic acid metabolism and signaling in iPLA2β (VIA)-deficient mice
Autor:
Mireille Basselin, Angelo O. Rosa, Epolia Ramadan, Yewon Cheon, Lisa Chang, Mei Chen, Deanna Greenstein, Mary Wohltmann, John Turk, Stanley I. Rapoport
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 11, Pp 3166-3173 (2010)
Ca2+-independent phospholipase A2β (iPLA2β) selectively hydrolyzes docosahexaenoic acid (DHA, 22:6n-3) in vitro from phospholipid. Mutations in the PLA2G6 gene encoding this enzyme occur in patients with idiopathic neurodegeneration plus brain iron
Externí odkaz:
https://doaj.org/article/9fad41192da04a42a58e196d444b349f
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 10, Pp 2940-2946 (2010)
Isotope feeding studies report a wide range of conversion fractions of dietary shorter-chain polyunsaturated fatty acids (PUFAs) to long-chain PUFAs, which limits assessing nutritional requirements and organ effects of arachidonic (AA, 20:4n-6) and d
Externí odkaz:
https://doaj.org/article/0cd848bb5e594c9cb01a2a8e42387932
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 8, Pp 2334-2340 (2010)
In vitro studies show that docosahexaenoic acid (DHA) can be released from membrane phospholipid by Ca2+-independent phospholipase A2 (iPLA2), Ca2+-independent plasmalogen PLA2 or secretory PLA2 (sPLA2), but not by Ca2+-dependent cytosolic PLA2 (cPLA
Externí odkaz:
https://doaj.org/article/a69f80b7e2bb49298265e8f26ce8c0b4
Autor:
Mireille Basselin, Hyung-Wook Kim, Mei Chen, Kaizong Ma, Stanley I. Rapoport, Robert C. Murphy, Santiago E. Farias
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 5, Pp 1049-1056 (2010)
Neuroinflammation, caused by 6 days of intracerebroventricular infusion of a low dose of lipopolysaccharide (LPS; 0.5 ng/h), stimulates brain arachidonic acid (AA) metabolism in rats, but 6 weeks of lithium pretreatment reduces this effect. To furthe
Externí odkaz:
https://doaj.org/article/fcee06a366a843889ffd8609ae883de3