Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Stanley G. Kimani"'
Autor:
Ke Geng, Sushil Kumar, Stanley G. Kimani, Vladyslav Kholodovych, Canan Kasikara, Kensaku Mizuno, Oleta Sandiford, Pranela Rameshwar, Sergei V. Kotenko, Raymond B. Birge
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The Tyro3, Axl, and Mertk (TAM) receptors are homologous type I receptor tyrosine kinases that have critical functions in the clearance of apoptotic cells in multicellular organisms. TAMs are activated by their endogenous ligands, growth arrest-speci
Externí odkaz:
https://doaj.org/article/dd66a583c5f546159d05fbd6fdef95a8
Autor:
Nicholas W. Colangelo, Tamjeed Saleh, Sushil Kumar, Canan Kasikara, Hong Li, Bryan T. Ciccarelli, Brendan Smith, Edouard I. Azzam, Stanley G. Kimani, Charalampos G. Kalodimos, Dhriti Mehta, Ke Geng, Viralkumar Davra, Raymond B. Birge
Publikováno v:
Mol Cancer Res
The Crk adaptor protein, a critical modifier of multiple signaling pathways, is overexpressed in many cancers where it contributes to tumor progression and metastasis. Recently, we have shown that Crk interacts with the peptidyl prolyl cis-trans isom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01cc56c08394b840bb80fb7dd6a428b1
https://europepmc.org/articles/PMC8045419/
https://europepmc.org/articles/PMC8045419/
Autor:
Grzegorz Rymarczyk, Wen-I Tsou, Allen Krantz, Michael Gray, Connor Devoe, Stanley G. Kimani, Sushil Kumar, Sergei V. Kotenko, Anita Antes, Ganapathy Sriram, Canan Kasikara, Kyle Schlunegger, Jeff Hutchins, Cyril Empig, Raymond B. Birge, Viralkumar Davra, Khanh-Quynh N. Nguyen, Andrzej Wilczynski, Ke Geng, Bruce Freimark
Publikováno v:
Mol Cancer Res
Tyro3, Axl, and Mertk (collectively TAM receptors) are three homologous receptor tyrosine kinases that bind vitamin K–dependent endogenous ligands, Protein S (ProS), and growth arrest–specific factor 6 (Gas6), and act as bridging molecules to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a00038ee8f56c5734be697b9e4c4bc8
https://doi.org/10.1158/1541-7786.mcr-16-0350
https://doi.org/10.1158/1541-7786.mcr-16-0350
Autor:
Canan Kasikara, Oleta A. Sandiford, Kensaku Mizuno, Stanley G. Kimani, Pranela Rameshwar, Sushil Kumar, Raymond B. Birge, Ke Geng, Vladyslav Kholodovych, Sergei V. Kotenko
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology, Vol 8 (2017)
The Tyro3, Axl, and Mertk (TAM) receptors are homologous type I receptor tyrosine kinases that have critical functions in the clearance of apoptotic cells in multicellular organisms. TAMs are activated by their endogenous ligands, growth arrest-speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008336d43206bc16f8076bbb57c4ac57
https://pubmed.ncbi.nlm.nih.gov/29176978
https://pubmed.ncbi.nlm.nih.gov/29176978
Autor:
Thomas W. Comollo, Stanley G. Kimani, Kamalendra Singh, Joseph R. Bertino, Sergei V. Kotenko, Vladyslav Kholodovych, Youyi Peng, Nitu Bansal, Sushil Kumar, Raymond B. Birge, Stefan G. Sarafianos, William J. Welsh
Publikováno v:
Scientific Reports
TAM receptors (Tyro-3, Axl, and Mertk) are a family of three homologous type I receptor tyrosine kinases that are implicated in several human malignancies. Overexpression of TAMs and their major ligand Growth arrest-specific factor 6 (Gas6) is associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2613827f3f3ff1d01b85e0e09be50cf
https://doi.org/10.1038/srep43908
https://doi.org/10.1038/srep43908
Publikováno v:
Cancers
Cancers, Vol 8, Iss 12, p 107 (2016)
Cancers, Vol 8, Iss 12, p 107 (2016)
The TAM family of receptors (i.e., Tyro3, Axl, and Mertk), and their ligands Growth arrest specific factor 6 (Gas6) and Protein S (Pros1) contribute to several oncogenic processes, such as cell survival, invasion, migration, chemo-resistance, and met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a880b41f16a63f796323b479967fc1
https://pubmed.ncbi.nlm.nih.gov/27916840
https://pubmed.ncbi.nlm.nih.gov/27916840
Autor:
Andrej Boháč, Mariana S. De Lorenzo, Stanley G. Kimani, Mainul Hoque, Ke Geng, Yun-Juan Chang, Sushil Kumar, Raymond B. Birge, Viralkumar Davra, Anita Lewis-Antes, Sergei V. Kotenko, Canan Kasikara, Shenyan Wang, Wen-I Tsou
Publikováno v:
Cell Communication and Signaling : CCS
Background Tyro3, Axl, and Mertk (TAMs) are a family of three conserved receptor tyrosine kinases that have pleiotropic roles in innate immunity and homeostasis and when overexpressed in cancer cells can drive tumorigenesis. Methods In the present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10be0ede4c1edc8bbfc00eaa078a1769
https://pubmed.ncbi.nlm.nih.gov/27595981
https://pubmed.ncbi.nlm.nih.gov/27595981
Autor:
Stanley G. Kimani, Canan Kasikara, Sushil Kumar, Ganapathy Sriram, Yi-Yi Wu, Raymond B. Birge, Ke Geng
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
Frontiers in Immunology
Frontiers in Immunology
The rapid and efficient clearance of apoptotic cells results in the elimination of auto-antigens and provides a strong anti-inflammatory and immunosuppressive signal to prevent autoimmunity. While professional and non-professional phagocytes utilize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c528fb8697b0bd2d90b47b661732e6
http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00566/full
http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00566/full
Autor:
Bin Lu, Yongzhang Liu, Wen-I Tsou, Sukhwinder Singh, Khanh Quynh N. Nguyen, Stanley G. Kimani, Shelly Hsieh, Raymond B. Birge, Daniel A. Calarese, Yi Wu, Sergei V. Kotenko, Steve C. Almo, Scott J. Garforth
MERTK, a member of the TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinases, has complex and diverse roles in cell biology. On the one hand, knock-out of MERTK results in age-dependent autoimmunity characterized by failure of apoptotic cell clearanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290ce4a57814fe77eb2bc31b96af0136
https://europepmc.org/articles/PMC4162176/
https://europepmc.org/articles/PMC4162176/
Publikováno v:
Handbook of Photomedicine ISBN: 9780429193842
Photodynamic therapy (PDT) is a photochemistry-based technology that utilizes the absorption of light by a photosensitizer (PS), initiating a photochemical process and resulting in localized treatment. Current PDT regimens produce this effect in two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17530dbc7bafb7dbaa4923a70f237069
https://doi.org/10.1201/b15582-36
https://doi.org/10.1201/b15582-36