Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Stanley FA"'
Autor:
Jace Jones-Tabah, Kathy He, Nathan Karpilovsky, Konstantin Senkevich, Ghislaine Deyab, Isabella Pietrantonio, Thomas Goiran, Yuting Cousineau, Daria Nikanorova, Taylor Goldsmith, Esther del Cid Pellitero, Carol X.-Q. Chen, Wen Luo, Zhipeng You, Narges Abdian, Jamil Ahmad, Jennifer A. Ruskey, Farnaz Asayesh, Dan Spiegelman, Stanley Fahn, Cheryl Waters, Oury Monchi, Yves Dauvilliers, Nicolas Dupré, Irina Miliukhina, Alla Timofeeva, Anton Emelyanov, Sofya Pchelina, Lior Greenbaum, Sharon Hassin-Baer, Roy N. Alcalay, Austen Milnerwood, Thomas M. Durcan, Ziv Gan-Or, Edward A. Fon
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-21 (2024)
Abstract Background Variants in the CTSB gene encoding the lysosomal hydrolase cathepsin B (catB) are associated with increased risk of Parkinson’s disease (PD). However, neither the specific CTSB variants driving these associations nor the functio
Externí odkaz:
https://doaj.org/article/e2786b44f0ab42b995b54fb1787459cd
Autor:
Philip Kam-Tao Li, Jack Kit-Chung Ng, Guang-yan Cai, Wei Chen, Kai Ming Chow, Stanley Fan, John Cijiang He, Lai Seong Hooi, York Pei, Boon Wee Teo, Muh Geot Wong, I-Wen Wu, Jianhui Zhou, Na Tian, Zhiming Ye, Xueqing Yu
Publikováno v:
Kidney Diseases, Pp 1-14 (2024)
Background: Chronic kidney disease (CKD) continues to be a significant global public health issue. The escalating burden of CKD is probably driven by the aging population and the rising prevalence of diabetes. CKD not only adversely impacts an indivi
Externí odkaz:
https://doaj.org/article/0ea1939371be403fa1ed2d51a1614bde
Autor:
Paul E. Greene, Stanley Fahn, David Eidelberg, Kimberly B. Bjugstad, Robert E. Breeze, Curt R. Freed
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Cell transplants are being developed for patients with Parkinson disease (PD) who have insufficient benefit with standard medical treatment. We describe the clinical features of five patients who developed persistent dyskinesias after fetal
Externí odkaz:
https://doaj.org/article/644271643da147bbb1f839328f6c42be
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-4 (2021)
Oleh Hornykiewicz (November 17, 1926–May 26, 2020), by demonstrating the loss of dopamine neurons in Parkinson’s disease, introducing the effort to treat the disorder with L-DOPA, and other innovative research, improved the lives of countless ind
Externí odkaz:
https://doaj.org/article/91270f69b044485b982fedb524e7a89f
Autor:
Aaron S. Schwartz-Duval, Christian J. Konopka, Parikshit Moitra, Enrique A. Daza, Indrajit Srivastava, Elyse V. Johnson, Taylor L. Kampert, Stanley Fayn, Anand Haran, Lawrence W. Dobrucki, Dipanjan Pan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Intracellular generation of gold nanoparticles has drawn attention but toxic effects have limited potential applications. Here, the authors report on the delivery of ionic gold with PEG resulting in faster synthesis and reduced toxicity due to lower
Externí odkaz:
https://doaj.org/article/ed78eaa00a594fb28473531f16e63f69
Autor:
Farah Gul Khan, Stanley Fan
Publikováno v:
SAGE Open Medical Case Reports, Vol 10 (2022)
Paradoxical reaction (also known as Jarisch–Herxheimer reaction) is a self-limited response to endotoxin released from dead bacteria after starting treatment and is characterized by constitutional symptoms such as fever, headache, dizziness and exa
Externí odkaz:
https://doaj.org/article/841e5c35a3374e4593b23f81645bb477
Autor:
Lindsay C. Fadel, Ivany V. Patel, Jonathan Romero, I-Chih Tan, Shelli R. Kesler, Vikram Rao, S. A. Amali S. Subasinghe, Russell S. Ray, Jason T. Yustein, Matthew J. Allen, Brian W. Gibson, Justin J. Verlinden, Stanley Fayn, Nicole Ruggiero, Caitlyn Ortiz, Elizabeth Hipskind, Aaron Feng, Chijindu Iheanacho, Alex Wang, Robia G. Pautler
Publikováno v:
Biosensors, Vol 12, Iss 8, p 616 (2022)
Anesthesia is often used in preclinical imaging studies that incorporate mouse or rat models. However, multiple reports indicate that anesthesia has significant physiological impacts. Thus, there has been great interest in performing imaging studies
Externí odkaz:
https://doaj.org/article/e3590e0019ec447e8aabbbe88387c59e
Autor:
Lorraine N Clark, Robin Chan, Rong Cheng, Xinmin Liu, Naeun Park, Nancy Parmalee, Sergey Kisselev, Etty Cortes, Paola A Torres, Gregory M Pastores, Jean P Vonsattel, Roy Alcalay, Karen Marder, Lawrence L Honig, Stanley Fahn, Richard Mayeux, Michael Shelanski, Gilbert Di Paolo, Joseph H Lee
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125204 (2015)
Variants in GBA are associated with Lewy Body (LB) pathology. We investigated whether variants in other lysosomal storage disorder (LSD) genes also contribute to disease pathogenesis.We performed a genetic analysis of four LSD genes including GBA, HE
Externí odkaz:
https://doaj.org/article/494bdd70e05b44d699035586fa58b9f0
Autor:
Stanley Falkow
Publikováno v:
mBio, Vol 3, Iss 5 (2012)
ABSTRACT In mid-1974, soon after the first recombinant DNA molecules were replicated in Escherichia coli, scientists called for, and observed, a voluntary moratorium on certain experiments. One goal of the moratorium was to hold a conference (Asiloma
Externí odkaz:
https://doaj.org/article/785ec124a2d44d43a5bc8ecdbf1db73c
Autor:
Wim Van Biesen, John D Williams, Adrian C Covic, Stanley Fan, Kathleen Claes, Monika Lichodziejewska-Niemierko, Christian Verger, Jurg Steiger, Volker Schoder, Peter Wabel, Adelheid Gauly, Rainer Himmele, EuroBCM Study Group
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17148 (2011)
BackgroundEuvolemia is an important adequacy parameter in peritoneal dialysis (PD) patients. However, accurate tools to evaluate volume status in clinical practice and data on volume status in PD patients as compared to healthy population, and the as
Externí odkaz:
https://doaj.org/article/4e30b62237974564b28da87cd02d9481