Výsledky vyhledávání - "Stanley E. Shackney"

Akademický článek

A Novel Subset of Human tumors that Simultaneously Overexpress Multiple E2F-responsive Genes Found in Breast, Ovarian, and Prostate Cancers

Autor: Stanley E. Shackney, Salim Akhter Chowdhury, Russell Schwartz

Publikováno v: Cancer Informatics, Vol 13s5 (2014)

Reasoning that overexpression of multiple E2F-responsive genes might be a useful marker for RB1 dysfunction, we compiled a list of E2F-responsive genes from the literature and evaluated their expression in publicly available gene expression microarra

Externí odkaz: https://doaj.org/article/69f30cba60cc4215ae7a8e2292a33fc8

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Classifying the Progression of Ductal Carcinoma from Single-Cell Sampled Data via Integer Linear Programming: A Case Study

Autor: Russell Schwartz, Daniele Catanzaro, Stanley E. Shackney, Alejandro A. Schäffer

Publikováno v: IEEE/ACM Transactions on Computational Biology and Bioinformatics. 13:643-655

Ductal Carcinoma In Situ (DCIS) is a precursor lesion of Invasive Ductal Carcinoma (IDC) of the breast. Investigating its temporal progression could provide fundamental new insights for the development of better diagnostic tools to predict which case

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fddd6f716a223e3e894d4b0a6a1d9c63
https://doi.org/10.1109/tcbb.2015.2476808

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HER2 expression as a potential marker for response to therapy targeted to the EGFR

Autor: C A Smith, Stanley E. Shackney, A A Pollice, David R. Emlet, Russell Schwartz, K A Brown

Publikováno v: British Journal of Cancer

Since human epidermal growth factor receptor 2 (HER2) is known to participate with the epidermal growth factor receptor (EGFR) in mitogenic signalling, we hypothesised that HER2 overexpression might indicate responsiveness to EGFR targeted therapies.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee091ad3d4429924a9410de8ef4d973
https://doi.org/10.1038/sj.bjc.6603078

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Guidelines for improving the reproducibility of quantitative multiparameter immunofluorescence measurements by laser scanning cytometry on fixed cell suspensions from human solid tumors

Autor: Stanley E. Shackney, David R. Emlet, Charles A. Smith, Kociban Dl, Kathryn A. Brown, Agnese A. Pollice

Publikováno v: Cytometry Part B: Clinical Cytometry. :10-19

Background: Laser scanning Cytometry (LSC) is a versatile technology that makes it possible to perform multiple measurements on individual cells and correlate them cell by cell with other cellular features. It would be highly desirable to be able to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2459e53b9432bb226c9a0b7b227ed994
https://doi.org/10.1002/cyto.b.20084

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The analysis of relapse-free survival curves: implications for evaluating intensive systemic adjuvant treatment regimens for breast cancer

Autor: R S Day, Stanley E. Shackney, W P Peters

Publikováno v: British Journal of Cancer

Results of adjuvant dose intensification studies in patients with localised breast cancer have raised questions regarding the clinical usefulness of this treatment strategy. Here, we develop and fit a natural history model for the time to clinical tu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f65cb61b1b6f5712da590600db0a3e0
https://doi.org/10.1038/sj.bjc.6602267

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A suitable method for identifying cell aggregates in laser scanning cytometry listmode data for analyzing disaggregated cell suspensions obtained from human cancers

Autor: Stanley E. Shackney, Deborah Kosiban, Kathryn A. Brown, Charles A. Smith, Agnese A. Pollice

Publikováno v: Cytometry. :10-23

Background The presence of cell aggregates in cell suspensions obtained from human solid tumors can interfere with the measurement of cell DNA content of cell singlets, and can confound multiparameter analysis of other measurements on the same cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::781d72ebca94461e109cf88d2c7e2a3d
https://doi.org/10.1002/cyto.b.20009

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A Novel Subset of Human tumors that Simultaneously Overexpress Multiple E2F-responsive Genes Found in Breast, Ovarian, and Prostate Cancers

Autor: Salim A. Chowdhury, Russell Schwartz, Stanley E. Shackney

Publikováno v: Cancer Informatics, Vol 13s5 (2014)
Cancer Informatics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f99d74e47db8572207fd3f04d20750e
https://doaj.org/article/69f30cba60cc4215ae7a8e2292a33fc8

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Distinctive patterns of Her-2/neu, c-myc, and cyclin D1 gene amplification by fluorescence in situ hybridization in primary human breast cancers

Autor: Kathryn A. Brown, Thomas B. Julian, Jan F. Silverman, Stanley E. Shackney, Agnese A. Pollice, Charles A. Smith, Sarita G. Singh, Ling Ping Gu, Norman Wolmark, Laura E. Janocko, Lillian Sweeney

Publikováno v: Cytometry. 46:136-149

Background: Human solid tumors undergo clonal evolution as they progress, but evidence for specific sequences of genetic changes that occur in individual tumors and are recapitulated in other tumors is difficult to obtain. Methods: Patterns of amplif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b21d5357c254200614b6b1ebe21a6fd
https://doi.org/10.1002/cyto.1098

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Multiparameter analysis of human epithelial tumor cell lines by laser scanning cytometry

Autor: Kathryn A. Brown, Agnese A. Pollice, Charles A. Smith, Daniel L. Farkas, Stanley E. Shackney, Jan F. Silverman

Publikováno v: Cytometry. 42:347-356

Laser scanning cytometry (LSC) is a relatively new slide-based technology developed for commercial use by CompuCyte (Cambridge, MA) for performing multiple fluorescence measurements on individual cells. Because techniques developed for performing fou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8cfef90508eb94a99008facdeb4fcb32
https://doi.org/10.1002/1097-0320(20001215)42:6<347::aid-cyto1001>3.0.co

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