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pro vyhledávání: '"Stanley C. Holt"'
Autor:
Stanley C. Holt
Publikováno v:
Bergey's Manual of Systematics of Archaea and Bacteria. :1-13
Publikováno v:
Journal of Periodontology. 80:1154-1165
Chronic oral infections that elicit host responses leading to periodontal disease are linked with various sequelae of systemic diseases. This report provides seminal information on the clinical and adaptive immunologic characteristics of a baboon mod
Autor:
Jeffrey L. Ebersole, Stanley C. Holt
Publikováno v:
Periodontology 2000. 38:72-122
Publikováno v:
Oral Microbiology and Immunology. 18:226-233
Porphyromonas gingivalis appears to be a major contributor to periodontal disease, especially soft tissue destruction, which is reflected by the ability to cause invasive, spreading lesions, and tissue inflammation in a murine abscess model. This stu
Publikováno v:
Infection and Immunity. 69:4465-4472
Treponema denticoladoes not appear to produce siderophores, so it must acquire iron by other pathways. Indeed,T. denticolahas been shown to have an iron-regulated 44-kDa outer membrane protein (HbpA) with hemin binding ability. To characterize the Hb
Publikováno v:
Acta Odontologica Scandinavica. 59:161-166
For decades, investigations have identified local and systemic humoral immune responses to microorganisms comprising the supra- and subgingival biofilms in the oral cavity. Inflammation and tissue destruction in the periodontium are accompanied by al
Publikováno v:
Oral Microbiology and Immunology. 15:172-180
We hypothesized that bacterial viability and strain characteristics of Porphyromonas gingivalis could affect the induction of pro-inflammatory mediator secretion by human gingival fibroblast cultures. Both killed and viable P. gingivalis elicited pro
Publikováno v:
Oral Microbiology and Immunology. 15:19-26
The hypothesis to be tested was that the microbiota and resulting local host inflammatory response characteristics in oral conditions of high levels of chronic gingival inflammation increases susceptibility to progressing periodontitis. This study us
Publikováno v:
Infection and Immunity. 67:5736-5746
This study investigated the characteristics of humoral immune responses to Treponema denticola following primary infection, reinfection, and active immunization, as well as immune protection in mice. Primary infection with T. denticola induced a sign