Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Stanley Brul"'
Autor:
Shiqi Liu, Paul Laman, Sean Jensen, Nicole N. van der Wel, Gertjan Kramer, Sebastian A.J. Zaat, Stanley Brul
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110002- (2024)
Summary: The presence of antibiotic persisters is one of the leading causes of recurrent and chronic diseases. One challenge in mechanistic research on persisters is the enrichment of pure persisters. In this work, we validated a proposed method to i
Externí odkaz:
https://doaj.org/article/850d50270bab49d187525b04b8452ea1
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109579- (2024)
Summary: The stringent response of bacteria to starvation and stress also fulfills a role in addressing the threat of antibiotics. Within this stringent response, (p)ppGpp, synthesized by RelA or SpoT, functions as a global alarmone. However, the eff
Externí odkaz:
https://doaj.org/article/fc72b00c30104d6f8352fa821e17ca20
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract Background Bacillus subtilis has been established as model microorganism for fundamental research in the laboratory on protein production/secretion and sporulation and as model bacterium for controlling spoilage in the food industry. It has
Externí odkaz:
https://doaj.org/article/49cd6ed5e1d4491cb39542102c5276e9
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108373- (2023)
Summary: Reactive oxygen species (ROS) produced as a secondary effect of bactericidal antibiotics are hypothesized to play a role in killing bacteria. If correct, ROS may play a role in development of de novo resistance. Here we report that single-ge
Externí odkaz:
https://doaj.org/article/e835b40b2fcc4389809a792350f7ce93
Autor:
Benjamin Yu, Julia Kanaan, Hannah Shames, James Wicander, Makunda Aryal, Yunfeng Li, George Korza, Stanley Brul, Gertjan Kramer, Yong-qing Li, Frank C. Nichols, Bing Hao, Peter Setlow
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
2Duf, named after the presence of a transmembrane (TM) Duf421 domain and a small Duf1657 domain in its sequence, is likely located in the inner membrane (IM) of spores in some Bacillus species carrying a transposon with an operon termed spoVA2mob. Th
Externí odkaz:
https://doaj.org/article/e359860d0fff42fbbfe298de7c358097
Autor:
Juan Wen, Norbert O. E. Vischer, Arend L. de Vos, Erik. M. M. Manders, Peter Setlow, Stanley Brul
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The SpoVA proteins make up a channel in the inner membrane (IM) of Bacillus subtilis spores. This channel responds to signals from activated germinant receptors (GRs), and allows release of Ca2+-DPA from the spore core during germination. In
Externí odkaz:
https://doaj.org/article/e0a7a41842094fa38df475c031467a03
Autor:
Sara Benito-Vaquerizo, Niels Nouse, Peter J. Schaap, Jeroen Hugenholtz, Stanley Brul, Ana M. López-Contreras, Vitor A. P. Martins dos Santos, Maria Suarez-Diez
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
One-carbon (C1) compounds are promising feedstocks for the sustainable production of commodity chemicals. CO2 is a particularly advantageous C1-feedstock since it is an unwanted industrial off-gas that can be converted into valuable products while re
Externí odkaz:
https://doaj.org/article/d32ab34b935d4ccdb81631b2aaf91d25
Autor:
Kitty Reemst, Sebastian Tims, Kit-Yi Yam, Mona Mischke, Jan Knol, Stanley Brul, Lidewij Schipper, Aniko Korosi
Publikováno v:
mSystems, Vol 7, Iss 3 (2022)
ABSTRACT Early-life stress (ELS) leads to increased vulnerability for mental and metabolic disorders. We have previously shown that a low dietary ω-6/ω-3 polyunsaturated fatty acid (PUFA) ratio protects against ELS-induced cognitive impairments. Du
Externí odkaz:
https://doaj.org/article/23160247443a4a1487f7881c7100eeff
Autor:
Yan Wang, Norbert O. E. Vischer, Demi Wekking, Alessandra Boggian, Peter Setlow, Stanley Brul
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Bacillus cereus spores, like most Bacillus spores, can survive for years and germinate when their surroundings become suitable, and germination proteins play an important role in the initiation of germination. Because germinated spores lose
Externí odkaz:
https://doaj.org/article/22dc1f2e820b4a12addf30f576255078
Autor:
Ewelina Weglarz-Tomczak, Jakub M. Tomczak, Michał Talma, Małgorzata Burda-Grabowska, Mirosław Giurg, Stanley Brul
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract An efficient treatment against a COVID-19 disease, caused by the novel coronavirus SARS-CoV-2 (CoV2), remains a challenge. The papain-like protease (PLpro) from the human coronavirus is a protease that plays a critical role in virus replicat
Externí odkaz:
https://doaj.org/article/d9f5c84dfce444628997569956549aae