Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Stanley Borowicz"'
Autor:
Stanley Borowicz, Daniel R Principe, Matthew J Dorman, Austin J McHenry, Gautam Sondarva, Sandeep Kumar, Vijayalakshmi Ananthanarayanan, Patricia E Simms, Ashley Hess, Ajay Rana
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252197 (2021)
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide. Though immune checkpoint inhibitors (ICIs) have revolutionized lung cancer therapy in recent years, there are several factors limiting the therapeutic efficacy
Externí odkaz:
https://doaj.org/article/25fe873de866459c8a595831290f2495
Autor:
Gautam Sondarva, Ajay Rana, Vijayalakshmi Ananthanarayanan, Austin J. McHenry, Matthew J. Dorman, Patricia E. Simms, Stanley Borowicz, Sandeep Kumar, Daniel R. Principe, Ashley Hess
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0252197 (2021)
PLoS ONE, Vol 16, Iss 6, p e0252197 (2021)
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide. Though immune checkpoint inhibitors (ICIs) have revolutionized lung cancer therapy in recent years, there are several factors limiting the therapeutic efficacy
Autor:
Alec M. Block, Colin Donahoe, Keith Schorsch, James W. Welsh, Aasma Khan, Linda Ritchie, Frank Melendez, Jaime Berumen Campo, Sanjay K. Singh, Richard Blankenbecler, Stanley Borowicz
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 108:E24-E25
Autor:
Robert A. Winn, Pei Ying Wu, Sereke Zerayesus, Michelle Van Scoyk, Xiangmin Zhao, Stanley Borowicz, Sreedevi Avasarala, Rama Kamesh Bikkavilli, Ke Tang, Marybeth Sechler, Manoj Kumar Karuppusamy Rathinam, Michael G. Edwards
Publikováno v:
The Journal of Biological Chemistry
Background: γ-Catenin is a tumor suppressor in lung cancer. Results: γ-Catenin is a novel regulator of HAI-1 and cell migration. Conclusion: γ-Catenin and HAI-1 regulate cell migration and sensitize NSCLC cells to c-MET inhibitor. Significance: Ta
Autor:
B. A. Parr, Manoj Kumar Karuppusamy Rathinam, Yves A. Lussier, Robert A. Winn, C Brzezinski, Stanley Borowicz, Wei Zhang, Jordi Tauler, Rama Kamesh Bikkavilli, Carlyne D. Cool, M. Van Scoyk, Michael G. Edwards, John J. Arcaroli, T. Zhou, Sreedevi Avasarala
Publikováno v:
Oncogene
Cellular senescence is an initial barrier for carcinogenesis. However, the signaling mechanisms that trigger cellular senescence are incompletely understood, particularlyin vivo. Here we identify Wnt7a as a novel upstream inducer of cellular senescen
Autor:
Stanley Borowicz, Alhareth Alsayed, Patricia E. Simms, Hiroaki Kataoka, Arkadiusz Z. Dudek, Gautam Sondarva, Vijayalakshmi Ananthanarayanan, Ashley Hess, Sandeep Kumar, Ajay Rana, Austin J. McHenry, Ravi Salgia, Jan Marusarz
Publikováno v:
Cancer Research. 78:5514-5514
Introduction: Non-small cell lung cancer (NSCLC) is the top cause of cancer-related mortality. We have identified a role for the tumor suppressor hepatocyte growth factor activator inhibitor type-1 (HAI-1) in human lung adenocarcinoma. HAI-1 loss res
Autor:
S. Moy, Elizabeth A. Myatt, Gyorgy Babnigg, Olufunmilayo I. Olopade, Rosemarie Wilton, Yinghua Chen, James D. Fackenthal, Marianne Schiffer, Fred J. Stevens, Stanley Borowicz, Frank R. Collart, William E. Boernke
Publikováno v:
Biochemical and Biophysical Research Communications. 345:188-196
BRCA1 is a large protein that exhibits a multiplicity of functions in its apparent role in DNA repair. Certain mutations of BRCA1 are known to have exceptionally high penetrance with respect to familial breast and ovarian cancers. The structures of t
Publikováno v:
Journal of Biological Chemistry. 279:6769-6777
c-Jun, a major component of the AP-1 transcription factor, is either pro- or anti-apoptotic with cellular determinants unknown. Nuclear estrogen receptor (ER), on the other hand, regulates gene expression through both estrogen response elements and A
Autor:
Guan Chen, Stanley Borowicz, Xiaomei Qi, Richard M. Schultz, Jiahuai Han, Rocky Pramanik, Divaker Choubey
Publikováno v:
Journal of Biological Chemistry. 278:4831-4839
p38 MAPK pathway signaling is known to participate in cell proliferation, apoptosis, and differentiation, in a manner dependent on the cellular context. The factors that determine the specific biological response in a given cell type, however, remain
Autor:
Rama Kamesh, Bikkavilli, Sreedevi, Avasarala, Michelle, Van Scoyk, Manoj Kumar, Karuppusamy Rathinam, Jordi, Tauler, Stanley, Borowicz, Robert A, Winn
Publikováno v:
Journal of visualized experiments : JoVE. (92)
Protein arginine methylation is one of the most abundant post-translational modifications in the nucleus. Protein arginine methylation can be identified and/or determined via proteomic approaches, and/or immunoblotting with methyl-arginine specific a