Zobrazeno 1 - 10
of 255
pro vyhledávání: '"Stanley A. Schwartz"'
Autor:
HariOm Singh, Chandrashekhar Jori, Shyamveer, Supriya D. Mahajan, Ravikumar Aalinkeel, Kathiravan Kaliyappan, Stanley A. Schwartz, Meenakshi Bhattacharya, Ruhi Shaikh, Madhukar Salve, Jyoti Deshmukh, Nemat Ali, Mohammad Khalid Parvez
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
HIV-associated lipodystrophy (HIVLD) is a metabolic condition with an irregularity in the production of lipoprotein particles, and its occurrence varies among HIV-infected patients. MTP and ABCG2 genes have a role in the transport of lipoproteins. Th
Externí odkaz:
https://doaj.org/article/667afad5a9384b1e88ad2e20bef2fcfc
Autor:
Satish Sharma, James Mohler, Supriya D. Mahajan, Stanley A. Schwartz, Liana Bruggemann, Ravikumar Aalinkeel
Publikováno v:
Microorganisms, Vol 11, Iss 6, p 1614 (2023)
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to nosocomial, chronic infections in clinical settings. Since the bacter
Externí odkaz:
https://doaj.org/article/114a3e605b4c4aac803ccc845f114787
Autor:
Satish Sharma, Katherine Cwiklinski, Supriya D. Mahajan, Stanley A. Schwartz, Ravikumar Aalinkeel
Publikováno v:
Cancers, Vol 15, Iss 3, p 902 (2023)
The standard of care chemotherapy drug presently used to treat castration-resistant prostate cancer (CRPC), docetaxel (Doc), also develops chemoresistance, thereby reducing its clinical utility. Since resistance to chemotherapy drugs can be overcome
Externí odkaz:
https://doaj.org/article/3dd741ab62ae4119b658599ca662e48e
Autor:
Liana Bruggemann, Zackary Falls, William Mangione, Stanley A. Schwartz, Sebastiano Battaglia, Ravikumar Aalinkeel, Supriya D. Mahajan, Ram Samudrala
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 997 (2023)
Pharmacogenomics is a rapidly growing field with the goal of providing personalized care to every patient. Previously, we developed the Computational Analysis of Novel Drug Opportunities (CANDO) platform for multiscale therapeutic discovery to screen
Externí odkaz:
https://doaj.org/article/6ff710e6963a4b23b0482be9c8c3119a
Autor:
Satish Sharma, Katherine Cwiklinski, Donald E. Sykes, Supriya D. Mahajan, Kent Chevli, Stanley A. Schwartz, Ravikumar Aalinkeel
Publikováno v:
Cancers, Vol 14, Iss 11, p 2704 (2022)
Galectins and prostate specific membrane antigen (PSMA) are glycoproteins that are functionally implicated in prostate cancer (CaP). We undertook this study to analyze the “PSMA-galectin pattern” of the human CaP microenvironment with the overarc
Externí odkaz:
https://doaj.org/article/e12c281c01fc4b0fbd49c1d473556f24
Autor:
Manoj J. Mammen, Jamil Ali, Amita Aurora, Umesh C. Sharma, Ravikumar Aalinkeel, Supriya D. Mahajan, Mark Sands, Stanley A. Schwartz
Publikováno v:
International Journal of Cell Biology, Vol 2021 (2021)
Mucus hypersecretion and chronic airway inflammation are standard characteristics of several airway diseases, such as chronic obstructive pulmonary disease and asthma. Increased mucus secretion from increased mucin gene expression in the airway epith
Externí odkaz:
https://doaj.org/article/7d6ae9affee34c51a0d15c45db53fa06
Autor:
B. Bindukumar, Stanley A. Schwartz, Madhavan P.N. Nair, Ravikumar Aalinkeel, Elzbieta Kawinski, Kailash C. Chadha
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 3, Pp 241-252 (2005)
Prostate-specific antigen (PSA) is a serine protease that is widely used as a surrogate marker in the early diagnosis and management of prostate cancer. The physiological relevance of tissue PSA levels and their role in prostate tumor growth and meta
Externí odkaz:
https://doaj.org/article/3a12e87987854dfa8526edc1ca237c41
Publikováno v:
Critical Reviews™ in Therapeutic Drug Carrier Systems. 40:69-100
Treatments for late-stage prostate cancer (CaP) have not been very successful. Frequently, advanced CaP progresses to castration-resistant prostate cancer (CRPC), with 50#37;-70% of patients developing bone metastases. CaP with bone metastasis-associ
Autor:
Khoo Ting Chean, Ravikumar Aalinkeel, Serfraz Abbasi, Anna V. Sharikova, Stanley A. Schwartz, Alexander Khmaladze, Supriya D. Mahajan
Publikováno v:
Biochemical and Biophysical Research Communications. 621:116-121
METH and HIV Tat treatment results in increased oxidative stress which affects cellular metabolism and causes DNA damage in the treated microglia. Both, METH ± HIV Tat impair mitochondrial respiration, leading to dysfunction in bioenergetics and inc
Autor:
Zhourui Xu, Ravikumar Aalinkeel, Supriya D. Mahajan, Nanxi Rao, Ting Chen, Yihang Jiang, Chengbin Yang, Gaixia Xu, Stanley A. Schwartz, Wing‐Cheung Law
Publikováno v:
Advanced Therapeutics.