Zobrazeno 1 - 10
of 672
pro vyhledávání: '"Stanley A. Schwartz"'
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract This review seeks to address major gaps and delays between our rapidly evolving body of knowledge on type 2 diabetes and its translation into real-world practice. Through updated and improved best practices informed by recent evidence and de
Externí odkaz:
https://doaj.org/article/9f103c194411419db10b0cd825e967ad
Autor:
Stanley S. Schwartz, Mary E. Herman
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Our understanding of type 2 diabetes (T2D) has evolved dramatically. Advances have upended entrenched dogmas pertaining to the onset and progression of T2D, beliefs that have prevailed from the early era of diabetes research—and continue to populat
Externí odkaz:
https://doaj.org/article/0234c742e4d948f29838835d92387764
Autor:
Satish Sharma, James Mohler, Supriya D. Mahajan, Stanley A. Schwartz, Liana Bruggemann, Ravikumar Aalinkeel
Publikováno v:
Microorganisms, Vol 12, Iss 10, p 1961 (2024)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/483e3f3670a1476393ab87ee7a740a3b
Autor:
HariOm Singh, Chandrashekhar Jori, Shyamveer, Supriya D. Mahajan, Ravikumar Aalinkeel, Kathiravan Kaliyappan, Stanley A. Schwartz, Meenakshi Bhattacharya, Ruhi Shaikh, Madhukar Salve, Jyoti Deshmukh, Nemat Ali, Mohammad Khalid Parvez
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
HIV-associated lipodystrophy (HIVLD) is a metabolic condition with an irregularity in the production of lipoprotein particles, and its occurrence varies among HIV-infected patients. MTP and ABCG2 genes have a role in the transport of lipoproteins. Th
Externí odkaz:
https://doaj.org/article/667afad5a9384b1e88ad2e20bef2fcfc
Autor:
Satish Sharma, James Mohler, Supriya D. Mahajan, Stanley A. Schwartz, Liana Bruggemann, Ravikumar Aalinkeel
Publikováno v:
Microorganisms, Vol 11, Iss 6, p 1614 (2023)
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to nosocomial, chronic infections in clinical settings. Since the bacter
Externí odkaz:
https://doaj.org/article/114a3e605b4c4aac803ccc845f114787
Autor:
Liana Bruggemann, Zackary Falls, William Mangione, Stanley A. Schwartz, Sebastiano Battaglia, Ravikumar Aalinkeel, Supriya D. Mahajan, Ram Samudrala
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 997 (2023)
Pharmacogenomics is a rapidly growing field with the goal of providing personalized care to every patient. Previously, we developed the Computational Analysis of Novel Drug Opportunities (CANDO) platform for multiscale therapeutic discovery to screen
Externí odkaz:
https://doaj.org/article/6ff710e6963a4b23b0482be9c8c3119a
Autor:
Manoj J. Mammen, Jamil Ali, Amita Aurora, Umesh C. Sharma, Ravikumar Aalinkeel, Supriya D. Mahajan, Mark Sands, Stanley A. Schwartz
Publikováno v:
International Journal of Cell Biology, Vol 2021 (2021)
Mucus hypersecretion and chronic airway inflammation are standard characteristics of several airway diseases, such as chronic obstructive pulmonary disease and asthma. Increased mucus secretion from increased mucin gene expression in the airway epith
Externí odkaz:
https://doaj.org/article/7d6ae9affee34c51a0d15c45db53fa06
Publikováno v:
Critical Reviews™ in Therapeutic Drug Carrier Systems. 40:69-100
Treatments for late-stage prostate cancer (CaP) have not been very successful. Frequently, advanced CaP progresses to castration-resistant prostate cancer (CRPC), with 50#37;-70% of patients developing bone metastases. CaP with bone metastasis-associ
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Diabetes mellitus is a world-wide epidemic and diabetic retinopathy, a devastating, vision-threatening condition, is one of the most common diabetes-specific complications. Diabetic retinopathy is now recognized to be an inflammatory, neuro-vascular
Externí odkaz:
https://doaj.org/article/370de3bc9b374b9e89e9a4b78d4ffefe
Autor:
Khoo Ting Chean, Ravikumar Aalinkeel, Serfraz Abbasi, Anna V. Sharikova, Stanley A. Schwartz, Alexander Khmaladze, Supriya D. Mahajan
Publikováno v:
Biochemical and Biophysical Research Communications. 621:116-121
METH and HIV Tat treatment results in increased oxidative stress which affects cellular metabolism and causes DNA damage in the treated microglia. Both, METH ± HIV Tat impair mitochondrial respiration, leading to dysfunction in bioenergetics and inc