Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Stanley A. Hefta"'
Autor:
Jimmy K. Eng, Alex J. Rai, Brian B. Haab, Rong Zeng, Valerie C. Wasinger, Henning Hermjakob, Joshua N. Adkins, Rajasree Menon, William S. Hancock, Helmut E. Meyer, Akhilesh Pandey, Stanley A. Hefta, Joel G. Pounds, Peipei Ping, Thomas W. Blackwell, David W. Speicher, Philip C. Andrews, Robert L. Moritz, Arie Admon, Rong Wang, Rolf Apweiler, Chi Yue Wu, Akira Tsugita, Jong Shin Yoo, Alexander I. Archakov, Gilbert S. Omenn, James S. Eddes, Harald Tammen, Xiaohong Qian, Xiaohang Zhao, Eugene A. Kapp, Daniel W. Chan, David J. States, Samir M. Hanash, Ruedi Aebersold, Young Ki Paik, Richard J. Simpson, Marcin Adamski, Michael Pisano, Ilan Beer
Publikováno v:
Exploring the Human Plasma Proteome
HUPO initiated the Plasma Proteome Project (PPP) in 2002. Its pilot phase has (1) evaluated advantages and limitations of many depletion, fractionation, and MS technology platforms; (2) compared PPP reference specimens of human serum and EDTA, hepari
Autor:
Yves Dubaquie, Leah-Ann Garulacan, Stanley A. Hefta, Ji Gao, Gregory J. Opiteck, Stephen M. Storm, Ashok Dongre, Donna M. Dambach
Publikováno v:
Methods. 35:291-302
Discovery of novel protein biomarkers is essential for successful drug discovery and development. These novel protein biomarkers may aid accelerated drug efficacy, response, or toxicity decision making based on their enhanced sensitivity and/or speci
Autor:
Stephen M. Storm, Yves Dubaquie, Ji Gao, Leah-Ann Garulacan, Gregory J. Opiteck, Stanley A. Hefta, Estelle M. Fach, Qing Xiao
Publikováno v:
Molecular & Cellular Proteomics. 3:1200-1210
The purpose of this study was to identify in vitro and then prioritize a tractable set of protein biomarker candidates of atherosclerosis that may eventually be developed to measure the extent, progression, regression, and stability of atheroscleroti
Autor:
Qing Xiao, Jeffrey D. Hulmes, Joseph Y. Lu, Deidra Bethea, Stanley A. Hefta, Paul S. Kayne, Estelle M. Fach, Gregory J. Opiteck, Keith Ho
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 9:238-249
The discovery of new biomarkers will be an essential step to enhance our ability to better diagnose and treat human disease. The proteomics research community has recently increased its use of human blood (plasma/serum) as a sample source for these d
Autor:
Deidra Bethea, Deborah L. Ricci, Gregory J. Opiteck, Stanley A. Hefta, Jeffrey D. Hulmes, Shu-Pang Huang, Keith Ho
Publikováno v:
Clinical Proteomics. 1:17-31
In order to evaluate the critical components of the process necessary to preserve clinical plasma samples collected at research sites for proteomic analysis, various collection and preservation protocols with controlled experimentation were evaluated
Publikováno v:
Journal of Proteome Research. 2:643-649
Protein expression trends in yeast were monitored as a function of carbon source (glucose versus galactose) using multidimensional high performance liquid chromatography (HPLC) coupled to gas-phase fractionation, using relative intensity triggering (
Autor:
James X Pang, Tiffany R. Kline, Susan E. Kiefer, Stanley A. Hefta, Julie E Scheffler, Gregory J. Opiteck
Publikováno v:
Analytical Biochemistry. 315:183-188
A process to extract and enrich extracellular peptides and proteins from tissues should have broad utility in the burgeoning proteomics field. To address this need, a novel three-step protocol was developed to extract polypeptides from whole tissue s
Publikováno v:
Journal of Proteome Research. 1:161-169
A hypothesis was formed that it would be possible to isolate an adequate amount of protein from a patient, having normal renal function, to identify biological markers of a particular disease state using a variety of proteomics techniques. To support
Publikováno v:
Biopolymers. 60:206-211
The genome sequencing effort has helped spawn the burgeoning field of proteomics. This review article examines state-of-the-art proteomics methods that are helping change the discovery paradigm in a variety of biological disciplines and, in particula
Publikováno v:
Analytical Chemistry. 67:4549-4556
A microcapillary liquid chromatography (HPLC) system designed for the gradient elution of peptide and protein samples at flow rates < 1 microL/min has been coupled to a triple-sector quadrupole mass spectrometer via a simple sheathless electrospray i