Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Stanislawa Weremowicz"'
Autor:
Kornelia Polyak, Cameron Brennan, Rebecca Gelman, Jeffrey R. Marks, Robert C. Gentleman, Bin Feng, Stanislawa Weremowicz, Jun Yao
To identify genetic changes involved in the progression of breast carcinoma, we did cDNA array comparative genomic hybridization (CGH) on a panel of breast tumors, including 10 ductal carcinoma in situ (DCIS), 18 invasive breast carcinomas, and two l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507d0096302020c88b49cf4a7e11e9c3
https://doi.org/10.1158/0008-5472.c.6495372
https://doi.org/10.1158/0008-5472.c.6495372
Autor:
Pasi A. Jänne, Scott J. Rodig, Nathanael S. Gray, Neal Lindeman, Kwok-Kin Wong, Michel J. Eck, James G. Christensen, Keith Wilner, Stephanie Heon, Mohit Butaney, Stanislawa Weremowicz, Yun Xiao, Magda Stumpfova, Dalia Ercan, Takeshi Shimamura, Marzia Capelletti, Katsuhiro Okuda, Jinyan Du, J. Paul Marcoux, Christopher Lathan, Wei Zheng, Sarah Nikiforow, Masahiko Yanagita, Atsuko Ogino, Jussi Koivunen, Takaaki Sasaki
PDF file - 560K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074b0a9b7ca2d2c042c3218606e3117f
https://doi.org/10.1158/0008-5472.22388459
https://doi.org/10.1158/0008-5472.22388459
Autor:
Kornelia Polyak, Jun Yao, Henry Long, Shenglin Mei, Cameron Brennan, Shoji Yamamoto, Laura Mulvey, Stanislawa Weremowicz, Ying Su, Kristopher Carver, Jee Hyun Kim, Taku Yoshida
Genetically activated kinases have been attractive therapeutic targets in cancer due to the relative ease of developing tumor-specific treatment strategies for them. To discover novel putative oncogenic kinases, we identified 26 genes commonly amplif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6136648a27d622d6be752a07575a29b
https://doi.org/10.1158/0008-5472.c.6507492.v1
https://doi.org/10.1158/0008-5472.c.6507492.v1
Autor:
Kornelia Polyak, Cameron Brennan, Rebecca Gelman, Jeffrey R. Marks, Robert C. Gentleman, Bin Feng, Stanislawa Weremowicz, Jun Yao
segmented aCGH dataset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1297ddfae902ef123d61b74e0b86b9b6
https://doi.org/10.1158/0008-5472.22366989
https://doi.org/10.1158/0008-5472.22366989
Autor:
Kornelia Polyak, Jun Yao, Henry Long, Shenglin Mei, Cameron Brennan, Shoji Yamamoto, Laura Mulvey, Stanislawa Weremowicz, Ying Su, Kristopher Carver, Jee Hyun Kim, Taku Yoshida
Supplementary Table S1. Kinases with copy number gain and overexpression in breast cancer tested in shRNA screen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09218530295b19db0bf10905485e4685
https://doi.org/10.1158/0008-5472.22408257
https://doi.org/10.1158/0008-5472.22408257
Autor:
Kornelia Polyak, Jun Yao, Henry Long, Shenglin Mei, Cameron Brennan, Shoji Yamamoto, Laura Mulvey, Stanislawa Weremowicz, Ying Su, Kristopher Carver, Jee Hyun Kim, Taku Yoshida
Supplementary Figures S1-S4: Supplementary Figure S1. CLK2 copy number and gene expression in breast cancer. Supplementary Figure S2. Validation of shRNA screen results for CLK2. Supplementary Figure S3. EMT-related changes following downregulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7528b917113c2abef40d4fab2f1093c0
https://doi.org/10.1158/0008-5472.22408260
https://doi.org/10.1158/0008-5472.22408260
Autor:
Kwok-Kin Wong, Marzia Capelletti, Jinyan Du, Yun Xiao, Wei Zheng, Stanislawa Weremowicz, Jussi Koivunen, Mohit Butaney, Stephanie Heon, Dalia Ercan, Keith D. Wilner, Michael J. Eck, Christopher S. Lathan, Atsuko Ogino, Takaaki Sasaki, Neal I. Lindeman, Takeshi Shimamura, Magda Stumpfova, Katsuhiro Okuda, Scott J. Rodig, Sarah Nikiforow, Masahiko Yanagita, J. Paul Marcoux, Pasi A. Jänne, James G. Christensen, Nathanael S. Gray
Publikováno v:
Cancer Research. 71:6051-6060
Anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKI), including crizotinib, are effective treatments in preclinical models and in cancer patients with ALK-translocated cancers. However, their efficacy will ultimately be limited by the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e3f5caccea2e512372419bad8e5ba2
https://doi.org/10.1158/0008-5472.can-11-1340
https://doi.org/10.1158/0008-5472.can-11-1340
Autor:
Stanislawa Weremowicz, Peter J. Hulick, Joan M. Stoler, K.M. Noonan, D.J. Donovan, M. Listewnik, C. Ihm, S. Kulkarni
Publikováno v:
Cytogenetic and Genome Research
Approximately 15 patients with partial trisomy 9p involving de novo duplications have been previously described. Here, we present clinical, cytogenetic, FISH and aCGH findings in a patient with a de novo complex rearrangement in the short arm of chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560f7d6715ccfe83fb8099da62a1ff28
http://europepmc.org/articles/PMC3711006
http://europepmc.org/articles/PMC3711006
Autor:
Yuri Nikolsky, Erica L. Bauerlein, Daniel R. Carrasco, Kornelia Polyak, Jun Yao, Haiyan Chen, Min Qi Hu, William C. Hahn, Stanislawa Weremowicz, Shelia M. Violette, Craig Allred, Andrea S. Richardson, Danielle K. Carroll, Stuart J. Schnitt, Rebecca Gelman, Mina J. Bissell, Tatiana Nikolskaya
Publikováno v:
Cancer Cell. 13:394-406
The transition of ductal carcinoma in situ (DCIS) to invasive carcinoma is a key event in breast tumor progression that is poorly understood. Comparative molecular analysis of tumor epithelial cells from in situ and invasive tumors has failed to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b666f2ad57ef9809328693ae5c7d1bdf
https://doi.org/10.1016/j.ccr.2008.03.007
https://doi.org/10.1016/j.ccr.2008.03.007
Autor:
Marc Vidal, Greg Hinkle, Andrea L. Richardson, Thomas M. Roberts, Lauren Ambrogio, Sarah K. Sjostrom, Matthew Meyerson, Jesse S. Boehm, Levi A. Garraway, Heidi Greulich, William C. Hahn, Laura Mulvey, Rhine R. Shen, Jun Yao, So Young Kim, Kornelia Polyak, David E. Hill, Jennifer K. Grenier, Eric S. Lander, Tomoko Hirozane-Kishikawa, Jean J. Zhao, Ian F. Dunn, Carly J. Stewart, David E. Root, Ron Firestein, Stanislawa Weremowicz
Publikováno v:
Cell. 129(6):1065-1079
The karyotypic chaos exhibited by human epithelial cancers complicates efforts to identify mutations critical for malignant transformation. Here we integrate complementary genomic approaches to identify human oncogenes. We show that activation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee783059c07c9f9760c9e031d57d0373