Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Stanislaw Stepkowski"'
Autor:
Stanislaw Stepkowski, Dulat Bekbolsynov, Jared Oenick, Surina Brar, Beata Mierzejewska, Michael A. Rees, Obi Ekwenna
Publikováno v:
Vaccines, Vol 12, Iss 9, p 992 (2024)
Since their conception with the smallpox vaccine, vaccines used worldwide have mitigated multiple pandemics, including the recent COVID-19 outbreak. Insightful studies have uncovered the complexities of different functional networks of CD4 T cells (T
Externí odkaz:
https://doaj.org/article/d19b302e0bd548c9bf44640fff7ef346
Autor:
Dulat Bekbolsynov, Andrew Waack, Camryn Buskey, Shalmali Bhadkamkar, Keegan Rengel, Winnifer Petersen, Mary Lee Brown, Tanaya Sparkle, Dinkar Kaw, Fayeq Jeelani Syed, Saurabh Chattopadhyay, Ritu Chakravarti, Sadik Khuder, Beata Mierzejewska, Michael Rees, Stanislaw Stepkowski
Publikováno v:
Vaccines, Vol 12, Iss 1, p 91 (2024)
Immunosuppressed kidney transplant (KT) recipients produce a weaker response to COVID-19 vaccination than immunocompetent individuals. We tested antiviral IgG response in 99 KT recipients and 66 healthy volunteers who were vaccinated with mRNA-1273 M
Externí odkaz:
https://doaj.org/article/d1c7dbe44b1a4111a68f1e7bbd78df71
Autor:
Shungang Zhang, Joshua D. Breidenbach, Fatimah K. Khalaf, Prabhatchandra R. Dube, Chrysan J. Mohammed, Apurva Lad, Stanislaw Stepkowski, Terry D. Hinds, Sivarajan Kumarasamy, Andrew Kleinhenz, Jiang Tian, Deepak Malhotra, David J. Kennedy, Christopher J. Cooper, Steven T. Haller
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 7 (2020)
Background Renal artery stenosis is a common cause of renal ischemia, contributing to the development of chronic kidney disease. To investigate the role of local CD40 expression in renal artery stenosis, Goldblatt 2‐kidney 1‐clip surgery was perf
Externí odkaz:
https://doaj.org/article/7a62d09df586440d8cb9c24caff6ca62
Autor:
Mithun Khattar, Caitlin E Baum, Paul Schroder, Joshua D Breidenbach, Steven T Haller, Wenhao Chen, Stanislaw Stepkowski
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225624 (2019)
IL-21 is the most recently discovered common gamma-chain cytokine that promotes persistent T-cell responses in chronic infections, autoimmunity and cancer. However, the therapeutic potential of inhibiting the IL-21-BATF signaling axis, particularly i
Externí odkaz:
https://doaj.org/article/1af312a4034a401482b9ea7ee0f3c3c9
Autor:
Rachel M. Golonka, Beng San Yeoh, Piu Saha, Amira Gohara, Ramakumar Tummala, Stanislaw Stepkowski, Amit K. Tiwari, Bina Joe, Frank J. Gonzalez, Andrew T. Gewirtz, Matam Vijay-Kumar
Publikováno v:
Hepatology Communications. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c22aa323ec137a1cfa9599b402fbbf9
https://doi.org/10.1097/hc9.0000000000000166
https://doi.org/10.1097/hc9.0000000000000166
Publikováno v:
Shock (Augusta, Ga.)
Sepsis, which kills over 200,000 patients and costs over $20 billion in the United States alone, presents a constant but preventable challenge in the healthcare system. Among the more challenging problems that it presents is misdiagnosis due to confl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8053809f3dfc703e37060b120267f3d
https://doi.org/10.1097/shk.0000000000001010
https://doi.org/10.1097/shk.0000000000001010
Publikováno v:
The Journal of Immunology. 190:195.10-195.10
IL21 is critical for T1D development in NOD mice, but its role in sustaining T cell responses against islets during T1D progression remains unexplored. Our studies show that diabetic NOD mice have high levels of serum IL21. We thus hypothesized that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64d4c271c245c205ec00b7f1f8c4d65c
https://doi.org/10.4049/jimmunol.190.supp.195.10
https://doi.org/10.4049/jimmunol.190.supp.195.10
Autor:
Mithun Khattar, Yoshihiro Miyahara, Paul Schroder, Beata Mierzejewska, Wenhao Chen, Stanislaw Stepkowski
Publikováno v:
The Journal of Immunology. 186:169.1-169.1
In the current study, we investigated the immune regulatory effects of TCR engagement simultaneously by an anti-TCRβ chain mAb (H57-597) without or with antigens. We found that administration of anti-mouse TCRβ mAb resulted in a preferential reduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f085a90c5d6114afc6cba62ec560d6ec
https://doi.org/10.4049/jimmunol.186.supp.169.1
https://doi.org/10.4049/jimmunol.186.supp.169.1
Autor:
Mithun Khattar, Guohua Wang, Yoshihiro Miyahara, Zhiyong Guo, Wenhao Chen, Stanislaw Stepkowski
Publikováno v:
The Journal of Immunology. 184:50.34-50.34
T-cells play a central role in cell mediated immune responses to foreign antigens. Optimal T-cell activation and expansion requires antigen recognition via cognate T-cell receptors (TCRs) along with co-stimulatory and cytokine signals. The cytokine s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ffa8ff28619f3f98fbf070260dcfae6
https://doi.org/10.4049/jimmunol.184.supp.50.34
https://doi.org/10.4049/jimmunol.184.supp.50.34
Publikováno v:
The Journal of Immunology. 182:47.10-47.10
The development of inducible Foxp3+ regulatory T (iTreg) cells is reciprocally related to that of pro-inflammatory T helper (Th) 17 cells. Both processes depend on transforming growth factor (TGF)-β. Recent studies indicated that interleukin (IL)-2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::008ccd2eed77ac639bdea2d705b71da1
https://doi.org/10.4049/jimmunol.182.supp.47.10
https://doi.org/10.4049/jimmunol.182.supp.47.10