Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Stanislava Jergova"'
Autor:
Kevin Liebmann, Mario A. Castillo, Stanislava Jergova, Thomas M. Best, Jacqueline Sagen, Dimitrios Kouroupis
Publikováno v:
Cells, Vol 13, Iss 6, p 484 (2024)
During the progression of knee osteoarthritis (OA), the synovium and infrapatellar fat pad (IFP) can serve as source for Substance P (SP) and calcitonin gene-related peptide (CGRP), two important pain-transmitting, immune, and inflammation modulating
Externí odkaz:
https://doaj.org/article/280d5e609f064e85bf3ca79565afb297
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282920 (2023)
The most frequently reported use of medical marijuana is for pain relief. However, its psychoactive component Δ9-tetrahydrocannabinol (THC) causes significant side effects. Cannabidiol (CBD) and β-caryophyllene (BCP), two other cannabis constituent
Externí odkaz:
https://doaj.org/article/d051c0443788447484372c79463fdb99
Publikováno v:
Bioengineering, Vol 10, Iss 1, p 84 (2023)
The underlying mechanisms of spinal cord injury (SCI)-induced chronic pain involve dysfunctional GABAergic signaling and enhanced NMDA signaling. Our previous studies showed that SCI hypersensitivity in rats can be attenuated by recombinant rat GABAe
Externí odkaz:
https://doaj.org/article/9398b5af6acb4b49bd9cbe4c631210b5
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
The insufficient pain relief provided by current pharmacotherapy for chronic neuropathic pain is a serious medical problem. The enhanced glutamate signaling via NMDA receptors appears to be one of the key events in the development of chronic pain. Al
Externí odkaz:
https://doaj.org/article/9fdd70d4cdfe44e4bdb30c97b12443c2
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Chronic neuropathic pain represents a clinically challenging state with a poor response to current treatment options. Long-term management of chronic pain is often associated with the development of tolerance, addiction, and other side effects, reduc
Externí odkaz:
https://doaj.org/article/cecad18a61d246d68f3d67da14870a87
Publikováno v:
Molecular pain. 18
Development of chronic pain has been attributed to dysfunctional GABA signaling in the spinal cord. Direct pharmacological interventions on GABA signaling are usually not very efficient and often accompanied by side effects due to the widespread dist
Autor:
H. Alex Choi, Adriel Barrios-Anderson, David A. Borton, Thomas N. Bryce, Mark J. Burish, Audrey Chun, Armin Curt, Z. David Luo, Megan R. Detloff, Anjalika Eeswara, Matthew A. Farmer, Matthew Fraser, Jared S. Fridley, Suzanne Gross, Young S. Gwak, Muhammad Abul Hasan, Georgene W. Hergenroeder, Melissa Hernandez, Juan J. Herrera, John D. Houle, Michèle Hubli, Claire E. Hulsebosch, Mohammed Sabah Jarjees, Stanislava Jergova, Irina V. Kalashnikova, Friederike Knerlich-Lukoschus, J.L.K. Kramer, Michael A. Lane, Joong Woo Leem, Allan D. Levi, L.D. Linde, Alexander R. Mikesell, Samuel T. Molina, Jonghyuck Park, Mariel Purcell, M. Ramer, Paul J. Reier, Jan Rosner, Carl Saab, Jacqueline Sagen, Christine N. Sang, Karl M. Schmitt, Lonnie D. Shea, Philip Siddall, Cheryl L. Stucky, Aditya Vedantam, Chuck Vierck, Aleksandra Vuckovic, Edgar T. Walters, Lyandysha V. Zholudeva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e3d49e1b597550bbb2aecbd478be293
https://doi.org/10.1016/b978-0-12-818662-6.09992-1
https://doi.org/10.1016/b978-0-12-818662-6.09992-1
Publikováno v:
Spinal Cord Injury Pain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10f921037a48352f0784726fef7bea36
https://doi.org/10.1016/b978-0-12-818662-6.00020-0
https://doi.org/10.1016/b978-0-12-818662-6.00020-0
Autor:
Benjamin I. Schachner, Jacqueline Sagen, Suzanne Gross, Melissa Hernandez, Stanislava Jergova, Heidy Martinez
Publikováno v:
Frontiers in Pain Research. 2
Therapeutic strategies targeting phantom limb pain (PLP) provide inadequate pain relief; therefore, a robust and clinically relevant animal model is necessary. Animal models of PLP are based on a deafferentation injury followed by autotomy behavior.
Publikováno v:
Journal of neurotrauma. 38(6)
Neuropathic pain often accompanies the functional deficits associated with spinal cord injury (SCI) and further reduces a patient's quality of life. Clinical and pre-clinical research is beginning to highlight the beneficial role that rehabilitative