Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Stanislava I. Avramova"'
Autor:
Michela L. Renzulli, Luc Rocheblave, Stanislava I. Avramova, Elena Galletti, Daniele Castagnolo, Laura Maccari, Stefano Forli, Fabrizio Manetti, Federico Corelli, Maurizio Botta
Publikováno v:
ARKIVOC, Vol 2006, Iss 8, Pp 111-130 (2006)
Externí odkaz:
https://doaj.org/article/006b67a3750f47e7aed8ef6e6f872013
Publikováno v:
Journal of Heterocyclic Chemistry. 52:130-135
The reaction of 1-[ω-(N-acylated amino)alkyl]-3,4-dihydroisoquinolines (7a, 7b, 7c, 7d, 7e) with homophthalic anhydride (1) leads to the formation of 8-oxo-13a-[(N-acylated amino)alkyl]-8H-dibenzo[a,g]quinolizine-13-carboxylic acids (8a–e) with pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcf0b9868aafe21a2e79164f62471c4a
https://doi.org/10.1002/jhet.1965
https://doi.org/10.1002/jhet.1965
Autor:
Daniele Castagnolo, Giorgio Maccari, Stanislava I. Avramova, Maurizio Botta, Gianpietro Sgaragli, Lorenzo Contemori, Annalisa Neri
Publikováno v:
ACS Medicinal Chemistry Letters. 1:416-421
Three simplified "non-natural" natural taxanes, related to taxuspine X, were synthetized and assayed as P-glycoprotein (P-gp) inhibitors. One of them (6) proved to be a very efficient P-gp inhibitor with an IC50 = 7.2 × 10(-6) M. In addition, to rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44dff6eb9e53b72cdd2f497f76e6d16
https://doi.org/10.1021/ml100118k
https://doi.org/10.1021/ml100118k
Autor:
Maurizio Botta, Federico Corelli, Michela L. Renzulli, Elena Galletti, Stanislava I. Avramova
Publikováno v:
Tetrahedron Letters. 48:751-754
The stereoselective synthesis of an advanced intermediate of Taxuspine U and X has been accomplished using a ring closing metathesis strategy. The feasibility of ring closing metathesis in synthesizing highly constrained and functionalized macrocycle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dcf059f1da9aa506465547befe0bf8d
https://doi.org/10.1016/j.tetlet.2006.11.167
https://doi.org/10.1016/j.tetlet.2006.11.167
Publikováno v:
ChemInform. 46
Reaction of dihydroisoquinolines (I) with homophthalic anhydride (II) results in the diastereoselective formation of cis-dibenzoquinolizinecarboxylic acids (III).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbd34e648658e1aa87f27ea29abbff1a
https://doi.org/10.1002/chin.201524183
https://doi.org/10.1002/chin.201524183
Autor:
Luc Rocheblave, Michela L. Renzulli, Federico Corelli, Maurizio Botta, Stanislava I. Avramova
Publikováno v:
Tetrahedron Letters. 45:5155-5158
The synthesis of bicyclic 3,8-secotaxane diterpenoids, which includes Taxuspine U and X, has been achieved through an approach that involves a ring closing metathesis reaction as key step for the macrocycle formation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3b9ff9c4232ba4d327438693113ebc5
https://doi.org/10.1016/j.tetlet.2004.04.147
https://doi.org/10.1016/j.tetlet.2004.04.147
Autor:
Gianluca Giorgi, Marco Radi, Daniela Alderighi, Gianpietro Sgaragli, Stanislava I. Avramova, Elena Galletti, Chiara Ghiron, Federico Corelli, Michela L. Renzulli, Maurizio Botta
Publikováno v:
ChemMedChem. 3(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd4bb6b630ceb6f957f8e5b7e649b0c
https://pubmed.ncbi.nlm.nih.gov/18232049
https://pubmed.ncbi.nlm.nih.gov/18232049
Autor:
Daniele Castagnolo, Elena Galletti, Maurizio Botta, Michela L. Renzulli, Federico Corelli, Luc Rocheblave, Stanislava I. Avramova, Andrea Tafi
Molecular modelling studies on the interations between taxanes and tubulins, developed by us, revealed that modified Taxuspines U and X could adopt a conformation similar to that of the bioactive conformation of paclitaxel and could be well accommoda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf336a4f4c21026f7942cec974e3cd5
http://hdl.handle.net/11365/9062
http://hdl.handle.net/11365/9062
Autor:
Luc Rocheblave, Stefano Forli, Federico Corelli, Maurizio Botta, Laura Maccari, Michela L. Renzulli, Stanislava I. Avramova, Daniele Castagnolo, Fabrizio Manetti, Elena Galletti
Publikováno v:
ARKIVOC, Vol 2006, Iss 8, Pp 111-130 (2006)
The remarkable therapeutic importance of taxane diterpenoids as anticancer drugs and their challenging structural complexity have stimulated worldwide enormous efforts. Our group developed a theoretic quantitative model describing the relationship be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0bef6080c0cdbd72f670005b37c48f
http://hdl.handle.net/11365/21140
http://hdl.handle.net/11365/21140
Autor:
Federico Corelli, Maurizio Botta, Michela L. Renzulli, Stanislava I. Avramova, Luc Rocheblave
Publikováno v:
ChemInform. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1b05fea3e3429b1e34f4562eff06992
https://doi.org/10.1002/chin.200442197
https://doi.org/10.1002/chin.200442197