Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Stanislav Zelivianski"'
Autor:
Joelle P. Straehla, Danijela Dokic, Ashley Hardy, Omar Nunez, R Hamdan, Jacqueline S. Jeruss, Elizabeth Tarasewicz, Stanislav Zelivianski
Publikováno v:
Cancer Biology & Therapy. 15:1301-1311
Cyclin D1/CDK4 activity is upregulated in up to 50% of breast cancers and CDK4-mediated phosphorylation negatively regulates the TGFβ superfamily member Smad3. We sought to determine if CDK4 inhibition and doxorubicin chemotherapy could impact Smad3
Autor:
Jacqueline S. Jeruss, Ashley Hardy, Laura Matthews, Samir Alexandre Boukaidi, Stanislav Zelivianski, Anne E. Cooley
Publikováno v:
Fertility and Sterility. 97:440-444
Objective To examine the impact of hormones used for controlled ovarian hyperstimulation (COH) on normal and malignant breast cell growth and proliferation. Design In vitro study of cultured normal and malignant breast cell lines. Setting Academic me
Autor:
Surinder K. Batra, Fen Fen Lin, Li Zhang, Ralph J. Hauke, Rachel Schutte, Thomas L. Davis, Ming Fong Lin, Stanislav Zelivianski, Jeffrey S. Davis
Publikováno v:
Cancer Letters. 285:58-65
We examined the efficacy of combination treatments utilizing cytotoxic drugs plus inhibitors to members of the ErbB - ERK signal pathway in human prostate cancer (PCa) LNCaP C-81 cells. Under an androgen-reduced condition, 50 nM gemcitabine caused ab
Autor:
Dmitry Kondrikou, Tsukasa Igawa, Stanislav Zelivianski, Ming Fong Lin, Surinder K. Batra, Dev Karan, Ta Chun Yuan, Suresh Veeramani, Fen Fen Lin
Publikováno v:
Endocrine-Related Cancer. 13:151-167
KEYWORDS CLASSIFICATION: Adenocarcinoma;Androgens;Animals;Biology;Cell Differentiation;Chromogranin A;Chromogranins;Epithelial Cells;Humans;metabolism;Male;mechanisms of carcinogenesis;Mice;Mice,Inbred BALB C;Mice,Nude;Molecular Biology;Neurotensin;p
Autor:
Ralph J. Hauke, Ming-Shyue Lee, Vladimir Kakitelashvilli, Mark Kellerman, Ming Fong Lin, Thomas L. Davis, Matthew Spellman, Stanislav Zelivianski, Xia Wei Zhou, Esmeralda Lugo, Rodney J. Taylor
Publikováno v:
International Journal of Cancer. 107:478-485
Anticancer drugs docetaxel and vinorelbine suppress cell growth by altering microtubule assembly and activating the proapoptotic signal pathway. Vinorelbine and docetaxel have been approved for treating several advanced cancers. However, their effica
Publikováno v:
Oncogene. 21:3696-3705
Human prostatic acid phosphatase (PAcP) is a prostate epithelium-specific differentiation antigen. The cellular form of PAcP functions as a neutral protein-tyrosine phosphatase, and is involved in regulating prostate cell growth. Although some inform
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1491:123-132
Human prostatic acid phosphatase (PAcP) is a prostate epithelium-specific differentiation antigen. To understand the regulation of expression of the PAcP gene, we studied the cis-regulatory elements of its promoter. A DNA fragment from −2899 to +87
Publikováno v:
Biochemical and Biophysical Research Communications. 245:108-112
Human prostatic acid phosphatase (PAP) has been proposed to be a prostate-epithelium differentiation antigen and its expression can be regulated by androgen. Nevertheless, the regulatory mechanism at the molecular level is not completely understood.
Effect of infertility treatment and pregnancy-related hormones on breast cell proliferation in vitro
background: Breast cancer development involves a series of mutations in a heterogeneous group of proto-oncogenes/tumor suppressor genes that alter mammary cells to create a microenvironment permissive to tumorigenesis. Exposure to hormones during inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc06a921737bdf7a56f0a86157a2bfb
https://europepmc.org/articles/PMC3241605/
https://europepmc.org/articles/PMC3241605/
Publikováno v:
Molecular cancer research : MCR. 8(10)
Smad3, a component of the transforming growth factor β signaling cascade, contributes to G1 arrest in breast cancer cells. Cyclin D1/cyclin-dependent kinase 4 (CDK4) promotes G1-S–phase transition, and CDK phosphorylation of Smad3 has been associa