Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Stanislav Y Shvartsman"'
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 2, p e1010875 (2023)
From insects to mammals, oocytes and sperm develop within germline cysts comprising cells connected by intercellular bridges (ICBs). In numerous insects, formation of the cyst is accompanied by growth of the fusome-a membranous organelle that permeat
Externí odkaz:
https://doaj.org/article/187de88fa1344fd6b087477f6b939520
Autor:
Joseph Crapse, Nishant Pappireddi, Meera Gupta, Stanislav Y Shvartsman, Eric Wieschaus, Martin Wühr
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 8, Pp n/a-n/a (2021)
Abstract The famous Arrhenius equation is well suited to describing the temperature dependence of chemical reactions but has also been used for complicated biological processes. Here, we evaluate how well the simple Arrhenius equation predicts comple
Externí odkaz:
https://doaj.org/article/5fbb017fe2fd431ca3568fa583d6fd2e
Autor:
Rocky Diegmiller, Lun Zhang, Marcio Gameiro, Justinn Barr, Jasmin Imran Alsous, Paul Schedl, Stanislav Y Shvartsman, Konstantin Mischaikow
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008711 (2021)
Since the seminal 1961 paper of Monod and Jacob, mathematical models of biomolecular circuits have guided our understanding of cell regulation. Model-based exploration of the functional capabilities of any given circuit requires systematic mapping of
Externí odkaz:
https://doaj.org/article/62be1c007851437bbadeaa8318e00f40
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 8, p e1008049 (2020)
Tissue morphogenesis relies on repeated use of dynamic behaviors at the levels of intracellular structures, individual cells, and cell groups. Rapidly accumulating live imaging datasets make it increasingly important to formalize and automate the tas
Externí odkaz:
https://doaj.org/article/1be6a931df8643718b99209889d98c80
Autor:
Paul Villoutreix, Joakim Andén, Bomyi Lim, Hang Lu, Ioannis G Kevrekidis, Amit Singer, Stanislav Y Shvartsman
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 9, p e1005742 (2017)
Dynamical processes in biology are studied using an ever-increasing number of techniques, each of which brings out unique features of the system. One of the current challenges is to develop systematic approaches for fusing heterogeneous datasets into
Externí odkaz:
https://doaj.org/article/c203211d2e494da593eae1cc1083ceb5
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 9, Pp 1819-1826 (2007)
Physicochemical models of signaling pathways are characterized by high levels of structural and parametric uncertainty, reflecting both incomplete knowledge about signal transduction and the intrinsic variability of cellular processes. As a result, t
Externí odkaz:
https://doaj.org/article/bfb39b0aeb3444ffa4ca80d07d39c2c3
Autor:
Sayantan Dutta, Reza Farhadifar, Wen Lu, Gokberk Kabacaoğlu, Robert Blackwell, David B. Stein, Margot Lakonishok, Vladimir I. Gelfand, Stanislav Y. Shvartsman, Michael J. Shelley
Life in complex systems, such as cities and organisms, comes to a standstill when global coordination of mass, energy, and information flows is disrupted. Global coordination is no less important in single cells, especially in large oocytes and newly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a57141f5707f5b5bdbce0a12457ec9f5
https://doi.org/10.1101/2023.04.04.534476
https://doi.org/10.1101/2023.04.04.534476
Autor:
Caroline A. Doherty, Farners Amargant, Stanislav Y. Shvartsman, Francesca E. Duncan, Elizabeth R. Gavis
Publikováno v:
Trends Cell Biol
In most animals, the oocyte is the largest cell by volume. The oocyte undergoes a period of large-scale growth during its development, prior to fertilization. At first glance, tissues that support the development of the oocyte in different organisms
Autor:
Emily K. Ho, Harrison R. Oatman, Sarah E. McFann, Liu Yang, Heath E. Johnson, Stanislav Y. Shvartsman, Jared E. Toettcher
Positional information in developing tissues often takes the form of stripes of gene expression that mark the boundaries of a particular cell type or morphogenetic process. How stripes form is still in many cases poorly understood. Here we use optoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9527b17962c611e710641234cb83ce8f
https://doi.org/10.1101/2023.03.09.531972
https://doi.org/10.1101/2023.03.09.531972
Mutations in signal transduction pathways lead to various diseases including cancers. MEK1 kinase, encoded by the humanMAP2K1gene, is one of the central components of the MAPK pathway and more than a hundred somatic mutations inMAP2K1gene were identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bf77bef95e7151123911f6112c2f428
https://doi.org/10.1101/2023.03.09.531944
https://doi.org/10.1101/2023.03.09.531944