Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Stanislav Kler"'
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2021)
The small size and translucency of larval zebrafish (Danio rerio) have made it a unique experimental system to investigate whole-brain neural circuit structure and function. Still, the connectivity patterns between most neuronal types remain mostly u
Externí odkaz:
https://doaj.org/article/561e6c64baf64fd6958285545874304f
Publikováno v:
Frontiers in Neural Circuits, Vol 13 (2020)
The unique combination of small size, translucency, and powerful genetic tools makes larval zebrafish a uniquely useful vertebrate system to investigate normal and pathological brain structure and function. While functional connectivity can now be as
Externí odkaz:
https://doaj.org/article/7b01522c683b4c6aa8991eb32463d231
Autor:
Santanu Mukherjee, Mahmoud Abd-El-Latif, Michal Bronstein, Orly Ben-nun-Shaul, Stanislav Kler, Ariella Oppenheim
Publikováno v:
PLoS ONE, Vol 2, Iss 8, p e765 (2007)
SV40 is a small, non enveloped DNA virus with an icosahedral capsid of 45 nm. The outer shell is composed of pentamers of the major capsid protein, VP1, linked via their flexible carboxy-terminal arms. Its morphogenesis occurs by assembly of capsomer
Externí odkaz:
https://doaj.org/article/7b80db190f1a4d159ba748b82a09b169
Publikováno v:
Nanoscale. 14(32)
We report a new type of nanoparticle, consisting of a nucleic acid core (7500 nt) folded into a 35 nm DNA origami sphere, encapsulated by a capsid composed of all three SV40 virus capsid proteins. Compared to the prototype reported previously, whose
Autor:
Gabriel A. Frank, Stanislav Kler, Efrat Zlotkin-Rivkin, Yael Levi-Kalisman, Ran Zalk, Idit Kopatz
Publikováno v:
Nanoscale. 11:10160-10166
Here we show the encapsulation of 35 nm diameter, nearly-spherical, DNA origami by self-assembly of SV40-like (simian virus 40) particles. The self-assembly of this new type of nanoparticles is highly reproducible and efficient. The structure of thes
Publikováno v:
Frontiers in Neural Circuits
Frontiers in Neural Circuits, Vol 13 (2020)
Frontiers in Neural Circuits, Vol 13 (2020)
The unique combination of small size, translucency, and powerful genetic tools makes larval zebrafish a uniquely useful vertebrate system to investigate normal and pathological brain structure and function. While functional connectivity can now be as
Publikováno v:
ACS Chemical Biology. 8:2753-2761
Interest in the in vitro assembled SV40 particle stems from its use as a model for self-assembly,(1, 2) for production of protein-coated nanoparticles,(3, 4) and its potential as a vector for gene and drug delivery.(5) SV40 has human tropism, transdu
Autor:
Ariella Oppenheim, Adam Zlotnick, Stanislav Kler, Uri Raviv, Daniel Harries, Chenglei Li, Avi Ginsburg, Roi Asor
Publikováno v:
Journal of the American Chemical Society. 134:8823-8830
Remarkably, uniform virus-like particles self-assemble in a process that appears to follow a rapid kinetic mechanism. The mechanisms by which spherical viruses assemble from hundreds of capsid proteins around nucleic acid, however, are yet unresolved
Publikováno v:
Virology. 397(1):199-204
The capsid of SV40 virion is comprised of 72 pentamers of the major capsid protein, VP1. We examined the synergism between pentamer-pentamer interaction and pentamer-DNA interaction using a minimal system of purified VP1 and a linear dsDNA 600-mer, c
Publikováno v:
Nucleic Acids Research
'Nucleic Acids Research ', vol: 41, pages: 1569-1580 (2013)
'Nucleic Acids Research ', vol: 41, pages: 1569-1580 (2013)
Using small-angle X-ray scattering, we determined the three-dimensional packing architecture of the minichromosome confined within the SV40 virus. In solution, the minichromosome, composed of closed circular dsDNA complexed in nucleosomes, was shown