Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Stanislav I. Tomarev"'
Publikováno v:
Cells, Vol 10, Iss 7, p 1564 (2021)
The purpose of this study was to characterize the miRNA profile of purified retinal ganglion cells (RGC) from healthy and diseased rat retina. Diseased retina includes those after a traumatic optic nerve crush (ONC), and after ocular hypertension/gla
Externí odkaz:
https://doaj.org/article/7eed35465ea24a5cbfcac169a6efa054
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism.
Classically, the regulation of energy balance has been based on central and peripheral mechanisms sensing energy, nutrients, metabolites, and hormonal cues. Several cellular mechanisms at central level, such as hypothalamic AMP-activated protein kina
Autor:
Tatyana V. Michurina, Tatiana V. Tkatchenko, Andrei V. Tkatchenko, Grigori Enikolopov, Naoki Nakaya, Stanislav I. Tomarev
It is generally accepted that retinal neurogenesis in mammals ceases shortly after birth and that stem/progenitor cells found in the postnatal eyes of mice and humans are in the quiescent state. In the present study, we have investigated postnatal re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71c824ca761c4b3f91fc5acada3c86aa
https://doi.org/10.1101/2021.08.30.458213
https://doi.org/10.1101/2021.08.30.458213
Publikováno v:
Cells
Volume 10
Issue 7
Cells, Vol 10, Iss 1564, p 1564 (2021)
Volume 10
Issue 7
Cells, Vol 10, Iss 1564, p 1564 (2021)
The purpose of this study was to characterize the miRNA profile of purified retinal ganglion cells (RGC) from healthy and diseased rat retina. Diseased retina includes those after a traumatic optic nerve crush (ONC), and after ocular hypertension/gla
Autor:
Ismael González-García, Óscar Freire-Agulleiro, Naoki Nakaya, Francisco J. Ortega, Pablo Garrido-Gil, Laura Liñares-Pose, Johan Fernø, José Luis Labandeira-Garcia, Carlos Diéguez, Afia Sultana, Stanislav I. Tomarev, José Manuel Fernández-Real, Miguel López
Publikováno v:
Metabolism
BACKGROUND AND AIMS: Olfactomedin 2 (OLFM2; also known as noelin 2) is a pleiotropic protein that plays a major role in olfaction and Olfm2 null mice exhibit reduced olfactory sensitivity, as well as abnormal motor coordination and anxiety-related be
Autor:
Ben Mead, Stanislav I. Tomarev
Publikováno v:
Prog Retin Eye Res
Extracellular vesicles (EV), which include exosomes and microvesicles, are secreted from virtually every cell. EV contain mRNA, miRNA, lipids and proteins and can deliver this expansive cargo into nearby cells as well as over long distances via the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c284e82a24fc6276907076c4fe23f64
Publikováno v:
Investigative Ophthalmology & Visual Science
Investigative Opthalmology & Visual Science
Investigative Opthalmology & Visual Science
Purpose To determine whether priming of bone marrow mesenchymal stem cells (MSCs) by signals from injured retina, particularly tumor necrosis factor α (TNFα), increase their exosomes’ neuroprotective efficacy on retinal ganglion cells (RGCs). Met
Autor:
Ben Mead, Stanislav I. Tomarev
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 3, Pp 516-522 (2022)
Neural Regeneration Research
Neural Regeneration Research
miRNA are short non-coding RNA responsible for the knockdown of proteins through their targeting and silencing of complimentary mRNA sequences. The miRNA landscape of a cell thus affects the levels of its proteins and has significant consequences to
Publikováno v:
Investigative Ophthalmology & Visual Science
Investigative Opthalmology & Visual Science
Investigative Opthalmology & Visual Science
Purpose To investigate the benefit of bone marrow mesenchymal stem cell (BMSC)-derived small extracellular vesicles (sEV) as an intravitreal (ivit) therapy in two rat models of glaucoma and to determine and identify candidate miRNA involved in the me
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose The compound heterozygous mutations in the β subunit of chaperonin containing TCP-1 (CCT), encoded by CCT2, lead to the Leber congenital amaurosis (LCA). In this study, a cct2 mutant line of zebrafish was established to investigate the role