Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stanislav I. Shram"'
Autor:
Yurii A. Zolotarev, Vladimir A. Mitkevich, Stanislav I. Shram, Alexei A. Adzhubei, Anna P. Tolstova, Oleg B. Talibov, Alexander K. Dadayan, Nikolai F. Myasoyedov, Alexander A. Makarov, Sergey A. Kozin
Publikováno v:
Biomolecules, Vol 11, Iss 6, p 909 (2021)
One of the treatment strategies for Alzheimer’s disease (AD) is based on the use of pharmacological agents capable of binding to beta-amyloid (Aβ) and blocking its aggregation in the brain. Previously, we found that intravenous administration of t
Externí odkaz:
https://doaj.org/article/08035eaa9ffc4b28bcc34298430cb247
Autor:
Tatyana A. Kurgina, Stanislav I. Shram, Mikhail M. Kutuzov, Tatyana V. Abramova, Tatyana A. Shcherbakova, Ekaterina A. Maltseva, Vladimir V. Poroikov, Olga I. Lavrik, Vytas K. Švedas, Dmitry K. Nilov
Publikováno v:
Biochemistry. Biokhimiia. 87(8)
Previously, we have found that a nucleic acid metabolite, 7-methylguanine (7mGua), produced in the body can have an inhibitory effect on the poly(ADP-ribose) polymerase 1 (PARP1) enzyme, an important pharmacological target in anticancer therapy. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd583df87f40b7b425803f5d0dc4645
https://pubmed.ncbi.nlm.nih.gov/36171646
https://pubmed.ncbi.nlm.nih.gov/36171646
Autor:
Yurii A. Zolotarev, Stanislav I. Shram, Aleksandr K. Dadayan, Oleg V. Dolotov, Dmitriy D. Markov, Igor Yu. Nagaev, Vladimir S. Kudrin, Viktor B. Narkevich, Oleg Yu. Sokolov, Natalya V. Kost
Publikováno v:
Neuropeptides. 96
The mechanisms of the neuroprotective action of the hexapeptides HLDF-6 encoded by the amino acid sequence 41-46 of Human Leukemia Differentiation Factor and its homoserine derivative HLDF-6H were studied in an experimental 1-methyl-4-phenyl-1,2,3,6-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4bcd7118a9e4d7abb205c1a24c2c11
https://pubmed.ncbi.nlm.nih.gov/36280440
https://pubmed.ncbi.nlm.nih.gov/36280440
Autor:
Yurii A. Zolotarev, Stanislav I. Shram, Aleksandr K. Dadayan, Oleg V. Dolotov, Dmitriy D. Markov, Igor Yu. Nagaev, Vladimir S. Kudrin, Viktor B. Narkevich, Oleg Yu. Sokolov, Natalya V. Kost
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::156a29f3ee1885e689fcc6aaf42b2e95
https://doi.org/10.2139/ssrn.4163318
https://doi.org/10.2139/ssrn.4163318
Autor:
Stanislav I Shram, Sergey A. Kozin, Alexander A. Makarov, Yurii A Zolotarev, Alexei A. Adzhubei, Anna P. Tolstova, Alexander K Dadayan, Oleg Talibov, Vladimir A. Mitkevich, Nikolai F Myasoyedov
Publikováno v:
Biomolecules, Vol 11, Iss 909, p 909 (2021)
Biomolecules; Volume 11; Issue 6; Pages: 909
Biomolecules
Biomolecules; Volume 11; Issue 6; Pages: 909
Biomolecules
One of the treatment strategies for Alzheimer’s disease (AD) is based on the use of pharmacological agents capable of binding to beta-amyloid (Aβ) and blocking its aggregation in the brain. Previously, we found that intravenous administration of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504fb4e1fd5f64632e5d95964583c21d
https://www.mdpi.com/2218-273X/11/6/909
https://www.mdpi.com/2218-273X/11/6/909
Autor:
Vsevolod A Khalizev, Alexander V. Shipitsin, Elena A. Shirokova, Anastasia L. Khandazhinskaya, Marina K. Kukhanova, Stanislav I Shram, Maxim V. Jasko, Dmitry V. Yanvarev, Yuriy S Skoblov
Publikováno v:
Drug Metabolism and Disposition. 37:494-501
The main disadvantages of 3'-azido-3'-deoxythymidine (zidovudine, AZT), the most common anti-HIV drug, are toxicity and a short half-life in the organism. The introduction of an H-phosphonate group into the AZT 5' position resulted in significant imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84b51f4e498ea89904ebff71ae14ddb
https://doi.org/10.1124/dmd.108.022269
https://doi.org/10.1124/dmd.108.022269
Publikováno v:
FEBS Letters. 351:168-170
The phenomenon of supercooperativity in platelet aggregation is manifested by the occurence of clear-cut thresholds in dose—response relationships; in such cases the Hill coefficient has unusually high values. Approximation, by the Hill equation, o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7bf062ea4d35f45d95743e0a2865f0
https://doi.org/10.1016/0014-5793(94)00845-0
https://doi.org/10.1016/0014-5793(94)00845-0