Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Stanislav Drapela"'
Publikováno v:
Molecular Oncology, Vol 16, Iss 18, Pp 3295-3318 (2022)
Aging is the most robust risk factor for cancer development, with more than 60% of cancers occurring in those aged 60 and above. However, how aging and tumorigenesis are intertwined is poorly understood and a matter of significant debate. Metabolic c
Externí odkaz:
https://doaj.org/article/b6a87909aeda4e91b4ccc9ddfc5b4e00
Autor:
Didem Ilter, Stanislav Drapela, Tanya Schild, Nathan P. Ward, Emma Adhikari, Vivien Low, John Asara, Thordur Oskarsson, Eric K. Lau, Gina M. DeNicola, Melanie R. McReynolds, Ana P. Gomes
Publikováno v:
Redox Biology, Vol 61, Iss , Pp 102627- (2023)
Metabolic reprogramming and metabolic plasticity allow cancer cells to fine-tune their metabolism and adapt to the ever-changing environments of the metastatic cascade, for which lipid metabolism and oxidative stress are of particular importance. NAD
Externí odkaz:
https://doaj.org/article/e2c33671c9844c32a8eea52be1ef6e6d
Autor:
Miroslav Boudny, Jana Zemanova, Prashant Khirsariya, Marek Borsky, Jan Verner, Jana Cerna, Alexandra Oltova, Vaclav Seda, Marek Mraz, Josef Jaros, Zuzana Jaskova, Michaela Spunarova, Yvona Brychtova, Karel Soucek, Stanislav Drapela, Marie Kasparkova, Jiri Mayer, Kamil Paruch, Martin Trbusek
Publikováno v:
Haematologica, Vol 104, Iss 12 (2019)
Introduction of small-molecule inhibitors of B-cell receptor signaling and BCL2 protein significantly improves therapeutic options in chronic lymphocytic leukemia. However, some patients suffer from adverse effects mandating treatment discontinuation
Externí odkaz:
https://doaj.org/article/e872ad7d936f40299c20d4bb02b9ef06
Autor:
Stanislav Drapela, Ana P. Gomes
Publikováno v:
Nature Cancer. 4:442-443
Publikováno v:
Cancer Research. 83:LB281-LB281
Ovarian cancer accounts for the fifth most common cause of cancer death among women, despite being relatively rare. This is in large because majority of cases are diagnosed at advanced stage and frequently recur after primary treatment. Despite numer
Autor:
Hossein Kashfi, Nathan Ward, Didem Ilter, Stanislav Drapela, Aimee Falzone, Stephen Gardell, Gina M. DeNicola, Ana P. Gomes
Publikováno v:
Cancer Research. 83:2161-2161
Lung cancer is the second most diagnosed type of cancer and the leading cause of cancer-related mortality. 85% of all lung cancer cases are non-small cell lung cancer (NSCLC), a large proportion of which are only diagnosed at advanced stages (II-IV)
Autor:
Stanislav Drapela, Devesh Raizada, Ananya Mukherjee, Joanne Tejero, Didem Ilter, Jose Javier Bravo-Cordero, Ana P Gomes
Publikováno v:
Cancer Research. 83:65-65
Most cancer-related deaths are caused by recurrent metastatic disease with latency periods that range from years to even decades. This halt in disease progression is driven by cancer dormancy, a stage in which residual disease is present but remains
Autor:
Didem Ilter, Tanya Schild, Nathan P. Ward, Stanislav Drapela, Emma Adhikari, Vivien Low, Eric Le-Lau, Gina M. DeNicola, Melanie R. McReynolds, Ana P. Gomes
Metabolic reprogramming and metabolic plasticity allow cancer cells to fine-tune their metabolism to adapt to the ever-changing environments of the metastatic cascade, for which lipid metabolism and oxidative stress are of particular importance. Cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae375661c9b3cc6671efd973e6335634
https://doi.org/10.1101/2022.03.25.485887
https://doi.org/10.1101/2022.03.25.485887
Autor:
Ana P. Gomes, Stanislav Drapela
Publikováno v:
Curr Opin Syst Biol
Metastases represent a major cause of cancer-associated deaths. Despite extensive research, targeting metastasis remains the main obstacle in cancer therapy. Therefore, it is of tremendous importance to elucidate the mechanisms that impinge on the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11973f865c1162ed39b248bc9518eff4
https://europepmc.org/articles/PMC8535854/
https://europepmc.org/articles/PMC8535854/
Autor:
Zuzana Kahounová, Markéta Pícková, Stanislav Drápela, Jan Bouchal, Eva Szczyrbová, Jiří Navrátil, Karel Souček
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-12 (2023)
Abstract Despite the advancements made in the diagnosis and treatment of cancer, the stages associated with metastasis remain largely incurable and represent the primary cause of cancer-related deaths. The dissemination of cancer is facilitated by ci
Externí odkaz:
https://doaj.org/article/76914d3e92714ee7a0aaef1af6d4853f