Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Stanislav Bellaousov"'
Autor:
Wan-Jung C. Lai, Mohammad Kayedkhordeh, Erica V. Cornell, Elie Farah, Stanislav Bellaousov, Robert Rietmeijer, Enea Salsi, David H. Mathews, Dmitri N. Ermolenko
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
It was previously suggested that formation of RNA secondary structure tends to bring the 5′ and 3′ ends of RNA into close proximity. Here the authors use experimental and computational approaches to show that mRNAs and lncRNAs have an intrinsic p
Externí odkaz:
https://doaj.org/article/4cabaeef47a048fa92dd9b55643a6ce8
Autor:
Christopher Tucker, Soumyaroop Bhattacharya, Hironao Wakabayashi, Stanislav Bellaousov, Anatoliy Kravets, Stephen L. Welle, Jason Myers, Jeffrey J. Hayes, Michael Bulger, Elena Rustchenko
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Candida albicans is a diploid fungus and a predominant opportunistic human pathogen. Notably, C. albicans employs reversible chromosomal aneuploidies as a means of survival in adverse environments. We previously characterized transcription o
Externí odkaz:
https://doaj.org/article/865206d6096f4bdf8a6fbb1ffa550712
Autor:
Eric R. Gamache, Jung H. Doh, Justin Ritz, Alain Laederach, Stanislav Bellaousov, David H. Mathews, M. Joan Curcio
Publikováno v:
Viruses, Vol 9, Iss 5, p 93 (2017)
The genomic RNA of the retrotransposon Ty1 is packaged as a dimer into virus-like particles. The 5′ terminus of Ty1 RNA harbors cis-acting sequences required for translation initiation, packaging and initiation of reverse transcription (TIPIRT). To
Externí odkaz:
https://doaj.org/article/092065ad1c194d3f9c8436d34faf8610
Autor:
Megan L. Insco, Brian J. Abraham, Sara J. Dubbury, Ines H. Kaltheuner, Sofia Dust, Constance Wu, Kevin Y. Chen, David Liu, Stanislav Bellaousov, Anna M. Cox, Benjamin J. E. Martin, Tongwu Zhang, Calvin G. Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E. Esgdaille, Telmo Henriques, Kevin M. Brown, Stephen J. Chanock, Matthias Geyer, Karen Adelman, Phillip A. Sharp, Richard A. Young, Paul L. Boutz, Leonard I. Zon
Publikováno v:
Science
RNA surveillance pathways detect and degrade defective transcripts to ensure RNA fidelity. We found that disrupted nuclear RNA surveillance is oncogenic. Cyclin-dependent kinase 13 ( CDK13 ) is mutated in melanoma, and patient-mutated CDK13 accelerat
Autor:
Zhi-Wei Tan, Suzanne Walker, Steven P. Gygi, Craig J. Thomas, George Q. Fei, Sara E. S. Martin, Paul L. Boutz, Damien Y. Duveau, Stanislav Bellaousov, Joao A. Paulo
Publikováno v:
Nucleic Acids Research
Intron detention in precursor RNAs serves to regulate expression of a substantial fraction of genes in eukaryotic genomes. How detained intron (DI) splicing is controlled is poorly understood. Here we show that a ubiquitous post-translational modific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d859efaa69f4c49c0f414ad86cf5fa6
https://doi.org/10.1101/2020.03.27.012781
https://doi.org/10.1101/2020.03.27.012781
Autor:
Stanislav Bellaousov, Dmitri N. Ermolenko, David H. Mathews, Enea Salsi, Wan-Jung C. Lai, Robert A. Rietmeijer, Mohammad Kayedkhordeh, Elie Farah, Erica V. Cornell
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
The 5′ and 3′ termini of RNA play important roles in many cellular processes. Using Förster resonance energy transfer (FRET), we show that mRNAs and lncRNAs have an intrinsic propensity to fold in the absence of proteins into structures in which
Publikováno v:
RNA. 24:1555-1567
Nucleic acids can be designed to be nano-machines, pharmaceuticals, or probes. RNA secondary structures can form the basis of self-assembling nanostructures. There are only four natural RNA bases, therefore it can be difficult to design sequences tha
Autor:
Phillip A. Sharp, Chen Ky, Fabo T, Boutz Pl, Sofia Dust, Calvin G Ludwig, Karen Adelman, Matthias Geyer, Dianbo Liu, Brian J. Abraham, Stanislav Bellaousov, Carl Wu, Insco Ml, Leonard I. Zon, Telmo Henriques, Sara J. Dubbury, Richard A. Young
Transcriptional Cyclin Dependent Kinases modulate RNA Polymerase II function to impact gene expression. Here, we show that CDK13 is mutated in 4% of patient melanomas and mutation or downregulation is associated with poor overall survival. Mutant CDK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595dcc3f8fc50c7616838d3a4340c0fe
Autor:
Jeffrey J. Hayes, Elena Rustchenko, Hironao Wakabayashi, Stephen Welle, Anatoliy Kravets, Stanislav Bellaousov, Michael Bulger, Christopher Tucker, Jason R. Myers, Soumyaroop Bhattacharya
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Autor:
Scott D. Kennedy, David H. Mathews, Michael J. Lopez, Jason D. Tubbs, Stanislav Bellaousov, Jonathan L. Chen, Douglas H. Turner
Publikováno v:
Biochemistry
Knowledge of RNA structure is necessary to determine structure-function relationships and to facilitate design of potential therapeutics. RNA secondary structure prediction can be improved by applying constraints from nuclear magnetic resonance (NMR)