Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Stanisław Sobiak"'
Autor:
Paweł Waśniowski, Jolanta Czuczejko, Michał Chuchra, Mateusz Wędrowski, Dawid Marciniak, Stanisław Sobiak, Bogdan Małkowski
Publikováno v:
Pharmaceuticals, Vol 16, Iss 1, p 10 (2022)
[18F]F-DOPA is widely used in PET diagnostics. Diseases diagnosed with this tracer are schizophrenia, Parkinson’s disease, gliomas, neuroendocrine tumors, pheochromocytomas, and pancreatic adenocarcinoma. It should be noted that the [18F]F-DOPA tra
Externí odkaz:
https://doaj.org/article/2898f86e6e68476eba2b13d65cadaf1e
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 9, Pp o2791-o2791 (2012)
In the title compound, C18H20O3S, the rings are almost coplanar [inter-ring dihedral angle = 6.6 (2)°]. In the crystal, weak C—H...O hydrogen bonds between the methoxy groups connect adjacent molecules, giving chains which extend along [001].
Externí odkaz:
https://doaj.org/article/e4a2321eed8f40d8b873ac88e364dd12
Autor:
Maciej Karolak, Aleksandra Ilnicka, Przemysław Górski, Karol Jaroch, Stanisław Sobiak, Adrian Krajewski, Alina Jaroch, Tomasz Stefański, Anna Sloderbach
Publikováno v:
Pharmacological Reports. 68:1266-1275
For the first time combretastatins were isolated from African willow tree Combretum Caffrum. Subsequent studies have shown the impact of combretastatin A4 phosphate, a water-soluble prodrug, on endothelial cells in tumor vascular system. The same eff
Autor:
Dawid Łażewski, Stanisław Sobiak, Rafał Czajkowski, Tadeusz Tardowski, Małgorzata Grochocka, Lukasz Sobotta, Marcin Wierzchowski
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 202:111703
Despite the continuous development of medicine, there is still a lack of effective and fully safe protocols for the treatment of neoplastic diseases. The drug-drug conjugates approach seems to give a chance to obtain more efficient molecules. New alk
Autor:
Barbara Licznerska, Tomasz Stefański, Michał Cichocki, Stanisław Sobiak, Hanna Szaefer, Violetta Krajka-Kuźniak, Wanda Baer-Dubowska
Publikováno v:
Pharmacological Reports. 66:732-740
Background Resveratrol is a natural stilbene derivative whose chemopreventive activity has been well established. Our previous studies have shown that modification of the stilbene backbone with the methylthio group may influence selectivity and inhib
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1300 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The growing interest in anticancer hybrids in the last few years has resulted in a great number of reports on hybrid design, synthesis and bioevaluation. Many novel multi-target-directed drug candidates were synthesized, and their biological activiti
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:5117-5126
A series of trans-stilbene derivatives containing 4'-methylthio substituent were synthesized and evaluated for inhibitory activities on human recombinant cytochrome P450(s): CYP1A1, CYP1A2, and CYP1B1. CYP1A2-related metabolism of stilbene derivative
Autor:
Kvetoslava Burda, Lukasz Sobotta, Ewa Tykarska, Tomasz Goslinski, Michal Mikus, Maria Gdaniec, Piotr Fita, Wojciech Szczolko, Aleksandra Orzechowska, Tomasz Koczorowski, Jadwiga Mielcarek, Marcin Wierzchowski, Stanisław Sobiak
Publikováno v:
Tetrahedron Letters. 53:2040-2044
The synthesis and physicochemical properties of novel porphyrazines possessing an alternate system of two peripheral substituents, 2,5-dimethylpyrrol-1-yl and dimethylamino, are presented. All the macrocycles were subjected to HPLC purity studies. Sp
Publikováno v:
Crystal Growth & Design. 12:2133-2137
The first structural characterization of glycyrrhizic acid, its monoammonium salt (AGA), and the complex of the salt with p-aminobenzoic acid in the solid state is reported. X-ray crystallography r...
Autor:
Tomasz Goslinski, Krystyna Konopka, Mateusz Sciepura, Sebastian Lijewski, Jaroslaw Piskorz, Stanisław Sobiak, Paulina Skupin, Jadwiga Mielcarek, Maciej Korpusinski
Publikováno v:
Journal of Fluorine Chemistry. 135:265-271
Novel porphyrazines possessing fluoroalkylthio and dietherthio peripheral substituents were synthesized and tested from the peripheral substituent effects on their physical–chemical properties, including metal binding abilities and solvatochromic e