Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Stanisław Skóra"'
Autor:
Maja Sołtyka-Krajewska, Marcin Ziemniak, Anna Zawadzka-Kazimierczuk, Paulina Skrzypczyk, Ewelina Siwiak-Niedbalska, Anna Jaśkiewicz, Rafał Zieliński, Izabela Fokt, Stanisław Skóra, Wiktor Koźmiński, Krzysztof Woźniak, Waldemar Priebe, Beata Pająk-Tarnacka
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2240 (2024)
Background: One defining feature of various aggressive cancers, including glioblastoma multiforme (GBM), is glycolysis upregulation, making its inhibition a promising therapeutic approach. One promising compound is 2-deoxy-d-glucose (2-DG), a d-gluco
Externí odkaz:
https://doaj.org/article/6d606b7bd79e4c7ba8de139e5102bb5f
Autor:
Beata Pająk, Ewelina Siwiak-Niedbalska, Anna Jaśkiewicz, Maja Sołtyka, Rafał Zieliński, Tomasz Domoradzki, Izabela Fokt, Stanisław Skóra, Waldemar Priebe
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1749 (2021)
Over the last decade, we have seen tremendous progress in research on 2-deoxy-D-glucose (2-DG) and its analogs. Clinical trials of 2-DG have demonstrated the challenges of using 2-DG as a monotherapy, due to its poor drug-like characteristics, leadin
Externí odkaz:
https://doaj.org/article/0059a481e2a447b882323f913e1c01d8
Publikováno v:
Tetrahedron: Asymmetry. 13:2223-2228
The high-pressure intermolecular Diels–Alder reactions of sugar-derived dienes with N -phenylmaleimide are described and the crystal structure of a representative adduct is presented. The sugar matrix can be removed from the molecule, allowing the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43a0761e5f2bd513efd13187026b9740
https://doi.org/10.1016/s0957-4166(02)00583-9
https://doi.org/10.1016/s0957-4166(02)00583-9
Publikováno v:
Tetrahedron: Asymmetry. 12:1895-1905
The reaction of organometallic derivatives of monosaccharides with aldehydes catalyzed with BF3·OEt2 was studied. A significant difference in reactivity between the pyranosidic and furanosidic allyltins was noted. The former reacted readily with ald
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96e4d559f90ea1e27302b0ad2f57b533
https://doi.org/10.1016/s0957-4166(01)00331-7
https://doi.org/10.1016/s0957-4166(01)00331-7
Autor:
Stanisław Skóra, Sławomir Jarosz
Publikováno v:
Tetrahedron: Asymmetry. 12:1651-1656
Readily available unsaturated bicyclic ketones—obtained conveniently from sugar allyltins—are converted into highly oxygenated unsaturated decalins. The corresponding cis- and trans- diols resulting from oxidation of the double bond were obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62b80e30a17aa545b27c4bdd69c681ac
https://doi.org/10.1016/s0957-4166(01)00288-9
https://doi.org/10.1016/s0957-4166(01)00288-9
Publikováno v:
Tetrahedron: Asymmetry. 11:1997-2006
The transformation of sugar allyltin derivatives into enantiomerically pure dienes (R*–CHCH–CHCH2) is presented. The internal double bond with the trans-configuration is formed regardless of the configuration of the starting sugar allyltin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e10112085371949c66420c55dcf68962
https://doi.org/10.1016/s0957-4166(00)00135-x
https://doi.org/10.1016/s0957-4166(00)00135-x
Autor:
Stanisław Skóra, Slawomir Jarosz
Publikováno v:
Tetrahedron: Asymmetry. 11:1433-1448
Preparation of enantiomerically pure, highly oxygenated decalins via tandem Wittig-type Diels–Alder reactions from the corresponding sugar-derived dieno-phosphoranes and/or -phosphonates and sugar aldehydes is described. Application of the phosphon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4fd09bb0e5fdb695bbb0bb218f28217
https://doi.org/10.1016/s0957-4166(00)00084-7
https://doi.org/10.1016/s0957-4166(00)00084-7
Autor:
Stanisław Skóra, Sławomir Jarosz
Publikováno v:
Tetrahedron: Asymmetry. 11:1425-1432
Tandem Wittig-type Diels–Alder reactions between sugar derived phosphonates and dienoaldehydes obtained from sugar allyltins lead, with high stereoselectivity, to complex oxygenated perhydroindene derivatives with the trans junction between the fiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::870cee08105be951493e26fd56679dd1
https://doi.org/10.1016/s0957-4166(00)00083-5
https://doi.org/10.1016/s0957-4166(00)00083-5
Publikováno v:
Journal of Carbohydrate Chemistry. 18:961-974
Reaction of sugar derived phosphonates [Sug-C(O)CH2P(O)(OMe)2] with sugar aldehydes (Sug'-CHO) provides the higher enones of the general formula Sug-C(O)CH=CH-Sug' with the trans configuration of the double bond. The phosphonate method is superior to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::176ea92e8c671e927b38dc30547b6f71
https://doi.org/10.1080/07328309908544046
https://doi.org/10.1080/07328309908544046
Publikováno v:
ChemInform. 31
Reaction of sugar derived phosphonates [Sug-C(O)CH2P(O)(OMe)2] with sugar aldehydes (Sug'-CHO) provides the higher enones of the general formula Sug-C(O)CH=CH-Sug' with the trans configuration of the double bond. The phosphonate method is superior to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c77995cdbc9d76f6484bb7d9099c478e
https://doi.org/10.1002/chin.200012226
https://doi.org/10.1002/chin.200012226