Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Stanisław Deja"'
Autor:
Xiaorong Fu, Justin A. Fletcher, Stanisław Deja, Melissa Inigo-Vollmer, Shawn C. Burgess, Jeffrey D. Browning
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
BACKGROUND Hepatic de novo lipogenesis (DNL) and β-oxidation are tightly coordinated, and their dysregulation is thought to contribute to the pathogenesis of nonalcoholic fatty liver (NAFL). Fasting normally relaxes DNL-mediated inhibition of hepati
Externí odkaz:
https://doaj.org/article/759d699f134e4b338a78e82adc8cb48b
Autor:
Xiaorong Fu, Stanisław Deja, Justin A. Fletcher, Norma N. Anderson, Monika Mizerska, Gonçalo Vale, Jeffrey D. Browning, Jay D. Horton, Jeffrey G. McDonald, Matthew A. Mitsche, Shawn C. Burgess
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Fat synthesis is necessary for normal physiology, but its dysregulation contributes to the pathology of many diseases. Here, the authors report a high-resolution mass spectrometry approach that quantifies fat synthesis flux in humans and mice followi
Externí odkaz:
https://doaj.org/article/b1cab25a3bac4392a10db218cc30d323
Autor:
Stanisław Deja, Adam Litarski, Karolina Anna Mielko, Natalia Pudełko-Malik, Wojciech Wojtowicz, Adam Zabek, Tomasz Szydełko, Piotr Młynarz
Publikováno v:
Metabolites, Vol 11, Iss 11, p 767 (2021)
Renal cell carcinoma (RCC) is the most common form of kidney malignancy. RCC is more common among men with a 2/1 male/female incidence ratio worldwide. Given the underlying epidemiological differences in the RCC incidence between males and females, w
Externí odkaz:
https://doaj.org/article/87acef478051402aae3c68d39686ab82
Autor:
Joanna Teul, Stanisław Deja, Katarzyna Celińska-Janowicz, Adam Ząbek, Piotr Młynarz, Piotr Barć, Adam Junka, Danuta Smutnicka, Marzenna Bartoszewicz, Jerzy Pałka, Wojciech Miltyk
Publikováno v:
Pathogens, Vol 9, Iss 5, p 399 (2020)
Bacterial wound infections are a common problem associated with surgical interventions. In particular, biofilm-forming bacteria are hard to eradicate, and alternative methods of treatment based on covering wounds with vascularized flaps of tissue are
Externí odkaz:
https://doaj.org/article/044c206156a34610b2877c2aa2f4dec3
Autor:
Stanisław Deja, Piotr P Wieczorek, Marek Halama, Izabela Jasicka-Misiak, Paweł Kafarski, Anna Poliwoda, Piotr Młynarz
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e104084 (2014)
Fly agaric (Amanita muscaria) was investigated using a 1H NMR-based metabolomics approach. The caps and stems were studied separately, revealing different metabolic compositions. Additionally, multivariate data analyses of the fungal basidiomata and
Externí odkaz:
https://doaj.org/article/b47c2660a367492d837a8c7dd966edb9
Autor:
Stanisław Deja, Tomasz Dawiskiba, Waldemar Balcerzak, Magdalena Orczyk-Pawiłowicz, Mateusz Głód, Dorota Pawełka, Piotr Młynarz
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84637 (2013)
Thyroid cancer is the most common endocrine malignancy. However, more than 90% of thyroid nodules are benign. It remains unclear whether thyroid carcinoma arises from preexisting benign nodules. Metabolomics can provide valuable and comprehensive inf
Externí odkaz:
https://doaj.org/article/5f3aada3233842b0bdb5d7c3c552e89d
Publikováno v:
Cell Metabolism. 34:658-660
Autor:
Toshiharu Onodera, May-Yun Wang, Joseph M. Rutkowski, Stanislaw Deja, Shiuhwei Chen, Michael S. Balzer, Dae-Seok Kim, Xuenan Sun, Yu A. An, Bianca C. Field, Charlotte Lee, Ei-ichi Matsuo, Monika Mizerska, Ina Sanjana, Naoto Fujiwara, Christine M. Kusminski, Ruth Gordillo, Laurent Gautron, Denise K. Marciano, Ming Chang Hu, Shawn C. Burgess, Katalin Susztak, Orson W. Moe, Philipp E. Scherer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Adiponectin is a secretory protein, primarily produced in adipocytes. However, low but detectable expression of adiponectin can be observed in cell types beyond adipocytes, particularly in kidney tubular cells, but its local renal role is un
Externí odkaz:
https://doaj.org/article/6885cd75dd3641e481d840972315e815
Autor:
Nicole K.H. Yiew, Stanislaw Deja, Daniel Ferguson, Kevin Cho, Chaowapong Jarasvaraparn, Miriam Jacome-Sosa, Andrew J. Lutkewitte, Sandip Mukherjee, Xiaorong Fu, Jason M. Singer, Gary J. Patti, Shawn C. Burgess, Brian N. Finck
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108196- (2023)
Summary: The liver coordinates the systemic response to nutrient deprivation and availability by producing glucose from gluconeogenesis during fasting and synthesizing lipids via de novo lipogenesis (DNL) when carbohydrates are abundant. Mitochondria
Externí odkaz:
https://doaj.org/article/802c3f379cbe48bdb9a10949ed2a6500
Autor:
Adam, Ząbek, Ivana, Stanimirova, Stanisław, Deja, Wojciech, Barg, Aneta, Kowal, Anna, Korzeniewska, Magdalena, Orczyk-Pawiłowicz, Daniel, Baranowski, Zofia, Gdaniec, Renata, Jankowska, Piotr, Młynarz
Publikováno v:
Metabolomics
Chronic obstructive pulmonary disease, COPD, affects the condition of the entire human organism and causes multiple comorbidities. Pathological lung changes lead to quantitative changes in the composition of the metabolites in different body fluids.