Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Stan de Kleijn"'
1
Akademický článek
Acute and chronic effects of treatment with mesenchymal stromal cells on LPS-induced pulmonary inflammation, emphysema and atherosclerosis development.
Autor: P Padmini S J Khedoe, Stan de Kleijn, Annemarie M van Oeveren-Rietdijk, Jaap J Plomp, Hetty C de Boer, Melissa van Pel, Patrick C N Rensen, Jimmy F P Berbée, Pieter S Hiemstra
Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0183741 (2017)
COPD is a pulmonary disorder often accompanied by cardiovascular disease (CVD), and current treatment of this comorbidity is suboptimal. Systemic inflammation in COPD triggered by smoke and microbial exposure is suggested to link COPD and CVD. Mesenc
Externí odkaz: https://doaj.org/article/00a14caffefc41d2866b2355c541af93
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2
Akademický článek
IFN-γ-stimulated neutrophils suppress lymphocyte proliferation through expression of PD-L1.
Autor: Stan de Kleijn, Jeroen D Langereis, Jenneke Leentjens, Matthijs Kox, Mihai G Netea, Leo Koenderman, Gerben Ferwerda, Peter Pickkers, Peter W M Hermans
Publikováno v: PLoS ONE, Vol 8, Iss 8, p e72249 (2013)
During systemic inflammation different neutrophil subsets are mobilized to the peripheral blood. These neutrophil subsets can be distinguished from normal circulating neutrophils (CD16(bright)/CD62L(bright)), based on either an immature CD16(dim)/CD6
Externí odkaz: https://doaj.org/article/582d02cb1f4c4a78abe3a533e2d81527
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3
Akademický článek
Transcriptome kinetics of circulating neutrophils during human experimental endotoxemia.
Autor: Stan de Kleijn, Matthijs Kox, Iziah Edwin Sama, Janesh Pillay, Angela van Diepen, Martijn A Huijnen, Johannes G van der Hoeven, Gerben Ferwerda, Peter W M Hermans, Peter Pickkers
Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38255 (2012)
Polymorphonuclear cells (neutrophils) play an important role in the systemic inflammatory response syndrome and the development of sepsis. These cells are essential for the defense against microorganisms, but may also cause tissue damage. Therefore,
Externí odkaz: https://doaj.org/article/5bb750776f144f49a79a837690b2eea7
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4
Spleen-derived IFN-γ induces generation of PD-L1+-suppressive neutrophils during endotoxemia
Autor: Jelle Gerretsen, Stan de Kleijn, Jeroen D. Langereis, Peter Pickkers, Marien I. de Jonge, Matthijs Kox
Publikováno v: Journal of Leukocyte Biology, 102, 6, pp. 1401-1409
Journal of Leukocyte Biology, 102, 1401-1409
The immune inhibitory checkpoint molecule programmed death ligand (PD-L)-1 is increasingly recognized as an important player in the immune suppression observed in patients with sepsis, but its role has mainly been studied in monocytes. In an earlier
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c1a53f3f877d2975a06849a84ffe9b
https://doi.org/10.1189/jlb.3a0217-051rr
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5
A short-term extremely low frequency electromagnetic field exposure increases circulating leukocyte numbers and affects HPA-axis signaling in mice
Autor: B.M. Lidy Verburg-van Kemenade, Stan de Kleijn, Gerben Ferwerda, J.J.M. Cuppen, Tamas Kozicz, Jos Trentelman, Peter W. M. Hermans, Linda de Jager, Michelle Wiese
Publikováno v: Bioelectromagnetics. 37:433-443
There is still uncertainty whether extremely low frequency electromagnetic fields (ELF-EMF) can induce health effects like immunomodulation. Despite evidence obtained in vitro, an unambiguous association has not yet been established in vivo. Here, mi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7b6f98d4f7e7c29c59afc1c8e5fcf88
https://doi.org/10.1002/bem.21998
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6
Therapeutic Application of an Extract of Helicobacter pylori Ameliorates the Development of Allergic Airway Disease
Autor: Gerrit John-Schuster, Hermelijn H. Smits, Christian Taube, Pieter S. Hiemstra, Anne Müller, Tinne C.J. Mertens, Yolanda van Wijck, Stan de Kleijn
Publikováno v: Journal of Immunology, 200(5), 1570-1579
Epidemiological and experimental studies have shown that exposure to the gastric bacterium Helicobacter pylori, especially in early life, prevents the development of asthma. Recent mouse studies have shown that this protective effect does not require
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3707f55565ff1a00008c60b38e4504df
http://hdl.handle.net/1887/96056
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8
Spleen-derived IFN-γ induces generation of PD-L1
Autor: Jeroen D, Langereis, Peter, Pickkers, Stan, de Kleijn, Jelle, Gerretsen, Marien I, de Jonge, Matthijs, Kox
Publikováno v: Journal of leukocyte biology. 102(6)
The immune inhibitory checkpoint molecule programmed death ligand (PD-L)-1 is increasingly recognized as an important player in the immune suppression observed in patients with sepsis, but its role has mainly been studied in monocytes. In an earlier
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a0eb2a9a11168008a9e43007280e9183
https://pubmed.ncbi.nlm.nih.gov/28974543
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9
Acute and chronic effects of treatment with mesenchymal stromal cells on LPS-induced pulmonary inflammation, emphysema and atherosclerosis development
Autor: Hetty C. de Boer, Jaap J. Plomp, Melissa van Pel, Annemarie M. van Oeveren-Rietdijk, Stan de Kleijn, Patrick C.N. Rensen, P. Padmini S.J. Khedoe, Jimmy F.P. Berbée, Pieter S. Hiemstra
Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0183741 (2017)
PLoS ONE
PLoS ONE, 12(9)
Background COPD is a pulmonary disorder often accompanied by cardiovascular disease (CVD), and current treatment of this comorbidity is suboptimal. Systemic inflammation in COPD triggered by smoke and microbial exposure is suggested to link COPD and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c599bfea7254fe530205d6b3ca6a89e
http://europepmc.org/articles/PMC5598950?pdf=render
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10
Modulation of granulocyte kinetics by GM-CSF/IFN-gamma in a human LPS rechallenge model
Autor: Stan de Kleijn, Janesh Pillay, Vera M. Kamp, Jenneke Leentjens, Leo Koenderman, Matthijs Kox, Jeroen D. Langereis, Peter Pickkers, Mihai G. Netea
Publikováno v: Journal of Leukocyte Biology, 94, 3, pp. 513-20
Journal of Leukocyte Biology, 94, 513-20
Inflammation in response to infection or trauma can lead to CARS, which is characterized by leukocyte dysfunction. In this study, we used a human model system for CARS to study the effect of GM-CSF and IFN-γ treatment on this immunoparalyzed state.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98235c2b7126c4be74bf0ec4a7a4267a
https://doi.org/10.1189/jlb.0213066
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