Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Stan Yoo"'
Autor:
Adam G. Kreutzer, Gretchen Guaglianone, Stan Yoo, Chelsea Marie T. Parrocha, Sarah M. Ruttenberg, Ryan J. Malonis, Karen Tong, Yu-Fu Lin, Jennifer T. Nguyen, William J. Howitz, Michelle N. Diab, Imane L. Hamza, Jonathan R. Lai, Vicki H. Wysocki, James S. Nowick
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The assembly of the β-amyloid peptide (Aβ) to form oligomers and fibrils is closely associated with the pathogenesis and progression of Alzheimer’s disease. Aβ is a shape-shifting peptide capable of adopting many conformations and folds within t
Autor:
Kate J. McKnelly, Adam G. Kreutzer, William J. Howitz, Katelyn Haduong, Stan Yoo, Candace Hart, James S. Nowick
Publikováno v:
Biochemistry
Familial Alzheimer's disease (FAD) is associated with mutations in the β-amyloid peptide (Aβ) or the amyloid precursor protein (APP). FAD mutations of Aβ were incorporated into a macrocyclic peptide that mimics a β-hairpin to study FAD point muta
Autor:
Sheng Zhang, Stan Yoo, Dalton T. Snyder, Benjamin B. Katz, Amy Henrickson, Borries Demeler, Vicki H. Wysocki, Adam G. Kreutzer, James S. Nowick
Publikováno v:
Biochemistry
Aβ dimers are a basic building block of many larger Aβ oligomers and are among the most neurotoxic and pathologically relevant species in Alzheimer’s disease. Homogeneous Aβ dimers are difficult to prepare, characterize and study, because Aβ fo
Autor:
Kreutzer, Adam G., Guaglianone, Gretchen, Stan Yoo, Parrocha, Chelsea Marie T., Ruttenberg, Sarah M., Malonis, Ryan J., Tong, Karen, Yu-Fu Lin, Nguyen, Jennifer T., Howitz, William J., Diab, Michelle N., Hamza, Imane L., Lai, Jonathan R., Wysocki, Vicki H., Nowick, James S.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 5/30/2023, Vol. 120 Issue 22, p1-12, 66p
Autor:
Stan Yoo, James S. Nowick, William J. Howitz, Jonathan Lin, Li Xing, Adam G. Kreutzer, Grace Huizar, Michael A. Morris, Hannah Jusuf, Sheng Zhang, Jian-Guo Zheng, Gretchen Guaglianone
Publikováno v:
Biochemistry
Fluorescent derivatives of the β-amyloid peptides (Aβ) are valuable tools for studying the interactions of Aβ with cells. Facile access to labeled expressed Aβ offers the promise of Aβ with greater sequence and stereochemical integrity, without
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9989b1e5854bfdcca654482fa3733888
https://europepmc.org/articles/PMC9059633/
https://europepmc.org/articles/PMC9059633/
Autor:
Stan Yoo, Michael A. Morris, James S. Nowick, William J. Howitz, Jonathan Lin, Adam G. Kreutzer, Gretchen Guaglianone, Hannah Jusuf, Li Xing, Jian-Guo Zheng, Sheng Zhang, Grace Huizar
Publikováno v:
Biochemistry. 60:2272-2273
Autor:
Brittany A. Moser, Y. Escalante-Buendia, Bethany McGonnigal, Stan Yoo, K. M. Barker, Aaron P. Esser-Kahn, D. A. Boltz, B. J. Cassaidy, M.G. Rosenberger, Rachel C. Steinhardt
Publikováno v:
Science Advances. 6
Improving adjuvant responses is a promising pathway to develop vaccines against some pathogens (e.g., HIV or dengue). One challenge in adjuvant development is modulating the inflammatory response, which can cause excess side effects, while maintainin
Autor:
Stan Yoo, Adam G. Kreutzer, Patrick J. Salveson, Alexander Thuy-Boun, Borries Demeler, Sepehr Haerianardakani, James S. Nowick
Publikováno v:
J Am Chem Soc
Soluble oligomers of the β-amyloid peptide, Aβ, are associated with the progression of Alzheimer’s disease. Although many small molecules bind to these assemblies, the details of how these molecules interact with Aβ oligomers remain unknown. Thi
Publikováno v:
Biochemistry. 57:3861-3866
Advances in amyloid research rely on improved access to the β-amyloid peptide, Aβ. N-terminal methionine extended Aβ, Aβ(M1–42), is a readily expressed and widely used form of Aβ with comparable properties to the natural Aβ(1–42) peptide. E
Autor:
Imane L. Hamza, Ryan K. Spencer, Kate J. McKnelly, James S. Nowick, Adam G. Kreutzer, Stan Yoo, Patrick J. Salveson
Publikováno v:
Biochemistry
The absence of high-resolution structures of amyloid oligomers constitutes a major gap in our understanding of amyloid diseases. A growing body of evidence indicates that oligomers of the β-amyloid peptide Aβ are especially important in the progres