Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stan Stasinopoulos"'
Autor:
Mythily Mariasegaram, Christopher Robert Michael Gafforini, Robert L. Medcalf, Stan Stasinopoulos, Yoshikuni Nagamine
Publikováno v:
FEBS Journal. 277:1331-1344
Plasminogen activator inhibitor type 2 (PAI-2; SERPINB2) is a highly-regulated gene that is subject to both transcriptional and post-transcriptional control. For the latter case, inherent PAI-2 mRNA instability was previously shown to require a nonam
Autor:
Stan Stasinopoulos, Robert L. Medcalf
Publikováno v:
FEBS Journal. 272:4858-4867
Plasminogen activator inhibitor type-2 (PAI-2) is a nonconventional serine protease inhibitor (serpin) with unique and tantalizing properties that is generally considered to be an authentic and physiological inhibitor of urokinase. However, the fact
Publikováno v:
Nucleic Acids Research
The human prothrombin G20210A polymorphism located at the 3′ cleavage site of the mRNA results in elevated plasma prothrombin levels and increased risk of venous thrombosis. This polymorphism has been shown to directly influence a variety of proces
Autor:
Stan, Stasinopoulos, Mythily, Mariasegaram, Chris, Gafforini, Yoshikuni, Nagamine, Robert L, Medcalf
Publikováno v:
The FEBS journal. 277(5)
Plasminogen activator inhibitor type 2 (PAI-2; SERPINB2) is a highly-regulated gene that is subject to both transcriptional and post-transcriptional control. For the latter case, inherent PAI-2 mRNA instability was previously shown to require a nonam
Autor:
Stan, Stasinopoulos, Hoanh, Tran, Emily, Chen, Mythily, Sachchithananthan, Yoshikuni, Nagamine, Robert L, Medcalf
Publikováno v:
Progress in nucleic acid research and molecular biology. 80
Autor:
Hoanh Tran, Stan Stasinopoulos, Robert L. Medcalf, Yoshikuni Nagamine, Emily C Chen, Mythily Sachchithananthan
Publikováno v:
Progress in Nucleic Acid Research and Molecular Biology ISBN: 9780125400800
Coordinated and timely regulation of gene expression is all essential component of many aspects of physiology This is particularly relevant for proteases and protease inhibitors associated with fibrinolysis. The plasminogen activating family of prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ce2cdf894670fd8eb8710f0a2f914dd
https://doi.org/10.1016/s0079-6603(05)80005-4
https://doi.org/10.1016/s0079-6603(05)80005-4
Publikováno v:
The Journal of biological chemistry. 278(16)
Plasminogen activator inhibitor type 2 (PAI-2) is a serine protease inhibitor that is subject to regulation at the post-transcriptional level. At least two mRNA instability elements reside within the PAI-2 transcript; one in the coding region and ano
Autor:
Fabienne Maurer, Mythily Sachchithananthan, Angela M. Carter, Robert L. Medcalf, Stan Stasinopoulos
Publikováno v:
Thrombosis and haemostasis. 87(5)
SummaryThe G20210A polymorphism has been shown to alter the efficiency of prothrombin mRNA processing. Here we show that the G20210A mutation also alters prothrombin mRNA stability. Three-fold more prothrombin protein and mRNA were produced in NIH-3T