Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Stan Kamp"'
Autor:
Rebecca A. Wood, Lauren Guthridge, Emma Thurmond, Carla J. Guthridge, Joseph M. Kheir, Rebecka L. Bourn, Catriona A. Wagner, Hua Chen, Wade DeJager, Susan R. Macwana, Stan Kamp, Rufei Lu, Cristina Arriens, Eliza F. Chakravarty, Aikaterini Thanou, Joan T. Merrill, Joel M. Guthridge, Judith A. James
Publikováno v:
Journal of Translational Autoimmunity, Vol 4, Iss , Pp 100117- (2021)
SLE is a clinically heterogeneous disease characterized by an unpredictable relapsing-remitting disease course. Although the etiology and mechanisms of SLE flares remain elusive, Epstein-Barr virus (EBV) reactivation is implicated in SLE pathogenesis
Externí odkaz:
https://doaj.org/article/e09b2484b3954ebdbc388b9721939137
Autor:
Joan T Merrill, Eliza Chakravarty, Aikaterini Thanou, Teresa Aberle, Fredonna Carthen, Stan Kamp, Motolani E Ogunsanya
Publikováno v:
Lupus Science and Medicine, Vol 7, Iss 1 (2020)
ObjectiveAlthough SLE disproportionately affects minority racial groups, they are significantly under-represented in clinical trials in the USA. This may lead to misleading conclusions in race-based subgroup analyses. We conducted focus groups to eva
Externí odkaz:
https://doaj.org/article/ba481c137ec8478e89bf29ac6f29497e
Autor:
Joel M. Guthridge, Rufei Lu, Ly Thi-Hai Tran, Cristina Arriens, Teresa Aberle, Stan Kamp, Melissa E. Munroe, Nicolas Dominguez, Timothy Gross, Wade DeJager, Susan R. Macwana, Rebecka L. Bourn, Stephen Apel, Aikaterini Thanou, Hua Chen, Eliza F. Chakravarty, Joan T. Merrill, Judith A. James
Publikováno v:
EClinicalMedicine, Vol 20, Iss , Pp - (2020)
Background: The clinical and pathologic diversity of systemic lupus erythematosus (SLE) hinders diagnosis, management, and treatment development. This study addresses heterogeneity in SLE through comprehensive molecular phenotyping and machine learni
Externí odkaz:
https://doaj.org/article/cb790d3c24634179a0061b64ef7c3855
Autor:
Melissa E. Munroe, Derek Blankenship, Daniele DeFreese, Mohan Purushothaman, Wade DeJager, Susan Macwana, Joel M. Guthridge, Stan Kamp, Nancy Redinger, Teresa Aberle, Eliza F. Chakravarty, Cristina Arriens, Yanfeng Li, Hu Zeng, Kathleen A. McCarthy‐Fruin, Shirley‐Ann Osei‐Onomahm, Uma Thanarajasingam, Judith A. James, Eldon Jupe
Publikováno v:
Arthritis & Rheumatology. 75:723-735
SLE is marked by immune dysregulation linked to varied clinical disease activity. Using a unique longitudinal cohort of SLE patients, this study seeks to identify optimal immune mediators informing an empirically refined Flare Risk Index (FRI) reflec
Autor:
Rebecka L. Bourn, Joel M. Guthridge, Stan Kamp, Joan T. Merrill, Krista Bean, Melissa E. Munroe, Judith A. James, Susan R. Macwana, Sudhakar Sridharan, Rufei Lu, Hua Chen
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-4 (2019)
Scientific Reports
Scientific Reports
Systemic lupus erythematosus (SLE) flares elicit progressive organ damage, leading to disability and early mortality. This study evaluated clinical and immunologic factors associated with impending flare in the Biomarkers of Lupus Disease study. Auto
Autor:
Krista Bean, Susan R. Macwana, Joel M. Guthridge, Joan T. Merrill, Sudhakar Sridharan, Stan Kamp, Rebecka L. Bourn, Melissa E. Munroe, Rufei Lu, Hua Chen, Judith A. James
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Systemic lupus erythematosus (SLE) flares elicit progressive organ damage, leading to disability and early mortality. This study evaluated clinical and immunologic factors associated with impending flare in the Biomarkers of Lupus Disease study. Auto
Autor:
Aikaterini Thanou, Eliza F. Chakravarty, Motolani E. Ogunsanya, Fredonna Carthen, Stan Kamp, Judith A. James, Teresa Aberle, Joan T. Merrill, Cristina Arriens
Publikováno v:
Lupus Science and Medicine, Vol 7, Iss 1 (2020)
Lupus Science & Medicine
Lupus Science & Medicine
ObjectiveAlthough SLE disproportionately affects minority racial groups, they are significantly under-represented in clinical trials in the USA. This may lead to misleading conclusions in race-based subgroup analyses. We conducted focus groups to eva
Autor:
Susan R. Macwana, Wade DeJager, Rebecca A. Wood, Judith A. James, Stan Kamp, Aikaterini Thanou, Eliza F. Chakravarty, Rebecka L. Bourn, Lauren Guthridge, Joel M. Guthridge, Carla J. Guthridge, Joan T. Merrill, Catriona A. Wagner, Hua Chen, Emma Thurmond, Rufei Lu, Cristina Arriens, Joseph M Kheir
Publikováno v:
Journal of Translational Autoimmunity, Vol 4, Iss, Pp 100117-(2021)
Journal of Translational Autoimmunity
Journal of Translational Autoimmunity
SLE is a clinically heterogeneous disease characterized by an unpredictable relapsing-remitting disease course. Although the etiology and mechanisms of SLE flares remain elusive, Epstein-Barr virus (EBV) reactivation is implicated in SLE pathogenesis
Autor:
Joe Rawdon, Anca Askanase, Teresa Aberle, Stan Kamp, Joan T. Merrill, Stavros Stavrakis, Judith A. James, Aikaterini Thanou, Eliza F. Chakravarty, Cristina Arriens
Publikováno v:
Clinical Sciences.
Background Existing methods for grading lupus flares or improvement in disease activity require definition-based thresholds as increments of change. Visual analogue scales (VAS) allow rapid, continuous scaling of disease severity. We analyzed the per
Autor:
Wade DeJager, Rufei Lu, Aikaterini Thanou, Carla J. Guthridge, Hua Chen, E. Thurmond, Eliza F. Chakravarty, Cristina Arriens, Susan R. Macwana, Joan T. Merrill, Rebecka L. Bourn, Joel M. Guthridge, R. Wood, Stan Kamp, Judith A. James, L. Guthridge
Publikováno v:
FRIDAY, 15 JUNE 2018.
Background Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease oftentimes characterised by a waxing and waning disease course. However, mechanisms of disease flare remain elusive. Objectives This study examined relationships betw