Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Stan J. F. Hartman"'
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Akademický článek
A New Framework to Implement Model-Informed Dosing in Clinical Guidelines: Piperacillin and Amikacin as Proof of Concept
Autor: Stan J. F. Hartman, Joost G. E. Swaving, Stijn W. van Beek, Bianca D. van Groen, Marika de Hoop, Tjitske M. van der Zanden, Rob ter Heine, Saskia N. de Wildt
Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)
Background: Modeling and simulation is increasingly used to study pediatric pharmacokinetics, but clinical implementation of age-appropriate doses lags behind. Therefore, we aimed to develop model-informed doses using published pharmacokinetic data a
Externí odkaz: https://doaj.org/article/afbf1afcd27242b68dc6c6e9d324dabe
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2
Current Ceftriaxone Dose Recommendations are Adequate for Most Critically Ill Children: Results of a Population Pharmacokinetic Modeling and Simulation Study
Autor: Saskia N. de Wildt, Nienke N Hagedoorn, Parth J. Upadhyay, Stan J. F. Hartman, Michiel van der Flier, Roger J. M. Brüggemann, Catherijne A. J. Knibbe, Henriëtte A. Moll, Ron A. A. Mathôt, Michiel F. Schreuder
Publikováno v: Clinical Pharmacokinetics, 60(10), 1361-1372. Adis
Clinical Pharmacokinetics, 60, 1361-1372
Clinical Pharmacokinetics. ADIS INT LTD
Clinical Pharmacokinetics
Clinical Pharmacokinetics, 60, 10, pp. 1361-1372
Clinical pharmacokinetics, 60(10), 1361-1372. Adis International Ltd
Background and Objective Ceftriaxone is a cornerstone antibiotic for critically ill children with severe infections. Despite its widespread use, information on the pharmacokinetics of ceftriaxone is lacking in this population. We aimed to determine c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01506c8ad4d5427b7c33afcc6ef8ddc6
https://doi.org/10.1007/s40262-021-01035-9
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3
Pharmacokinetics and Target Attainment of Antibiotics in Critically Ill Children: A Systematic Review of Current Literature
Autor: Saskia N. de Wildt, Roger J. M. Brüggemann, L Orriëns, Stan J. F. Hartman, Michiel F. Schreuder, Nada Dia
Publikováno v: Clinical Pharmacokinetics, 59(2), 173-205. Adis
Clinical Pharmacokinetics, 59, 2, pp. 173-205
Clinical Pharmacokinetics, 59, 173-205
Clinical Pharmacokinetics
Background Pharmacokinetics (PK) are severely altered in critically ill patients due to changes in volume of distribution (Vd) and/or drug clearance (Cl). This affects the target attainment of antibiotics in critically ill children. We aimed to ident
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5496fa546028d628563b28e25644be2
https://doi.org/10.1007/s40262-019-00813-w
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4
External Validation of Model-Based Dosing Guidelines for Vancomycin, Gentamicin, and Tobramycin in Critically Ill Neonates and Children: A Pragmatic Two-Center Study
Autor: Tim Poel, Stan J. F. Hartman, Saskia N. de Wildt, Marika de Hoop, L Orriëns, Samanta M Zwaag
Publikováno v: Paediatric Drugs
Pediatric Drugs, 22(4), 433-444
Paediatric Drugs, 22, 433-444
Paediatric Drugs, 22, 4, pp. 433-444
Contains fulltext : 225119.pdf (Publisher’s version ) (Open Access) BACKGROUND: The Dutch Pediatric Formulary (DPF) increasingly bases its guidelines on model-based dosing simulations from pharmacokinetic studies. This resulted in nationwide dose c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4da90399411beb1c255ed264dfbc2e6
https://hdl.handle.net/2066/225119
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5
Proenkephalin as a new biomarker for pediatric acute kidney injury - reference values and performance in children under one year of age
Autor: Joost van Rosmalen, Nadies E C van de Water, Michiel F. Schreuder, Dick Tibboel, Saskia N. de Wildt, Stan J. F. Hartman, Oliver Hartmann, Joachim Struck, Janin Schulte, Remi Beunders, Peter Pickkers, Alexandra J M Zwiers
Publikováno v: Clinical Chemistry and Laboratory Medicine, 58(11), 1911-1919. De Gruyter
Clinical Chemistry and Laboratory Medicine, 58, 11, pp. 1911-1919
Clinical Chemistry and Laboratory Medicine, 58, 1911-1919
Objectives Acute kidney injury (AKI) is common in critically ill children, but current biomarkers are suboptimal. Proenkephalin A 119–159 (PENK) is a promising new biomarker for AKI in adults, but pediatric data is lacking. We determined PENK refer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04bf6e0a888c3bb55af8a231be42f450
https://doi.org/10.1515/cclm-2020-0381
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6
Population pharmacokinetics of intravenous cefotaxime indicates that higher doses are required for critically ill children
Autor: Stan J. F. Hartman, Parth J. Upadhyay, Ron A. A. Mathôt, Michiel van der Flier, Michiel F. Schreuder, Roger J. Brüggemann, Catherijne A. Knibbe, Saskia N. de Wildt
Publikováno v: Journal of Antimicrobial Chemotherapy, 77, 1725-1732
Journal of Antimicrobial Chemotherapy, 77, 6, pp. 1725-1732
Journal of Antimicrobial Chemotherapy, 77(6), 1725-1732. OXFORD UNIV PRESS
The Journal of antimicrobial chemotherapy, 77(6), 1725-1732. Oxford University Press
Journal of Antimicrobial Chemotherapy, 77(6), 1725-1732. Oxford University Press
Background Cefotaxime is frequently used in critically ill children, however pharmacokinetic (PK) studies to support adequate dosing in this patient population are limited. Objectives To characterize cefotaxime PK in critically ill children and evalu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4c6e373e3a403f9cfc33617411f764
http://hdl.handle.net/2066/251196
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Target attainment of cefotaxime in critically ill children with meningococcal septic shock as a model for cefotaxime dosing in severe pediatric sepsis
Autor: Stan J. F. Hartman, Birgit C. P. Koch, Navin P. Boeddha, Gertjan J. Driessen, Rogier Donders, Ebru Ekinci, Saskia N. de Wildt, Jan A. Hazelzet
Publikováno v: European Journal of Clinical Microbiology and Infectious Diseases, 38, 7, pp. 1255-1260
European Journal of Clinical Microbiology and Infectious Diseases, 38, 1255-1260
European Journal of Clinical Microbiology & Infectious Diseases, 38(7), 1255-1260. Springer-Verlag
European Journal of Clinical Microbiology & Infectious Diseases
Reduced target attainment of β-lactam antibiotics is reported in critically ill patients. However, as target attainment of cefotaxime in severely ill pediatric sepsis patients may differ from adults due to age-related variation in pharmacokinetics,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df27b191269bf55441b7cfd96789577a
https://doi.org/10.1007/s10096-019-03535-w
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8
The Oral Bioavailability and Metabolism of Midazolam in Stable Critically Ill Children: A Pharmacokinetic Microtracing Study
Autor: Stan J. F. Hartman, Catherijne A. J. Knibbe, Joost van Rosmalen, Bianca D van Groen, Saskia N. de Wildt, N. Harry Hendrikse, Karel Allegaert, Birgit C. P. Koch, Dick Tibboel, Albert D. Windhorst, Elke H. J. Krekels, Esther van Duijn, Miriam G. Mooij, Wouter H. J. Vaes
Publikováno v: Clinical Pharmacology and Therapeutics, 109(1), 140-149. Wiley-Blackwell
Clinical Pharmacology and Therapeutics, Epub 13 May
Clinical Pharmacology and Therapeutics, 109, 140-149
van Groen, B D, Krekels, E H J, Mooij, M G, van Duijn, E, Vaes, W H J, Windhorst, A D, van Rosmalen, J, Hartman, S J F, Hendrikse, N H, Koch, B C P, Allegaert, K, Tibboel, D, Knibbe, C A J & de Wildt, S N 2021, ' The Oral Bioavailability and Metabolism of Midazolam in Stable Critically Ill Children: A Pharmacokinetic Microtracing Study ', Clinical Pharmacology and Therapeutics, vol. 109, no. 1, pp. 140-149 . https://doi.org/10.1002/cpt.1890, https://doi.org/10.1002/cpt.1890
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics, 109, 1, pp. 140-149
Midazolam is metabolized by the developmentally regulated intestinal and hepatic drug-metabolizing enzyme cytochrome P450 (CYP) 3A4/5. It is frequently administered orally to children, yet knowledge is lacking on the oral bioavailability in term neon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b91723dc49e8ea4eb1c1336430edfbb
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/232102
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